Stem-loop sequence xtr-mir-196a

DescriptionXenopus tropicalis miR-196a stem-loop
Gene family MIPF0000031; mir-196
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-196_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

miR-196 is a non-coding RNA called a microRNA that has been shown to be expressed in human (MI0000238, MI0000279) and mouse (MI0000552, MI0000553). miR-196 appears to be a vertebrate specific microRNA and has now been predicted or experimentally confirmed in a wide range of vertebrate species (MIPF0000031). In many species the miRNA appears to be expressed from intergenic regions in HOX gene clusters. The hairpin precursors are predicted based on base pairing and cross-species conservation—their extents are not known. In this case the mature sequence is excised from the 5' arm of the hairpin. It has been suggested that a rare SNP (rs11614913) that overlaps hsa-mir-196a2 has been found to be associated with non-small cell lung carcinoma.

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   uu  -uau c       cu      u          a        g a   cuu 
5'   ug    c agcugau  gugguu agguaguuuc uguuguug g uug   u
     ||    | |||||||  |||||| |||||||||| |||||||| | |||    
3'   ac    g uugacug  cauuaa uccgucaaag acaacggc c aau   u
   cu  uucu c       --      u          a        g -   ucu 
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Genome context
Coordinates (JGI4.2) Overlapping transcripts
GL172862.1: 380414-380519 [+]
ENSXETT00000050678 ; hoxc9-201; intron 1

Mature sequence xtr-miR-196a

Accession MIMAT0003690

25 - 


 - 45

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Evidence experimental; Northern [1]
Predicted targets