Stem-loop sequence xtr-mir-338-2

AccessionMI0004954 (change log)
DescriptionXenopus tropicalis miR-338-2 stem-loop
Gene family MIPF0000097; mir-338
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled miR-338. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

miR-338 is a family of brain-specific microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interference. miR-338 is located in an intronic region within the gene for apoptosis-associated tyrosine kinase (AATK). It has been predicted that it may downregulate genes which have a downstream negative effect on AATK expression.

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         u   -       c ucu    gugc 
5' caacaa auc cugaugc g   gagu    g
   |||||| ||| ||||||| |   ||||     
3' guuguu uag gacuacg c   cucg    g
         u   u       a ---    aaag 
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Genome context
Coordinates (Xenopus_tropicalis_v9.1; GCA_000004195.3) Overlapping transcripts
chr9: 20077939-20077998 [+]
ENSXETT00000051846 ; lmtk2-201; intron 6
Database links

Mature sequence xtr-miR-338

Accession MIMAT0003665

39 - 


 - 60

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Evidence by similarity; MI0002066
Predicted targets