miRBase entry: mdv1-mir-M8

Stem-loop mdv1-mir-M8


Accession
MI0005100
Description
Mareks disease virus type 1 mdv1-mir-M8 precursor miRNA
Gene family
MIPF0000922; mir-M8


Sequence

auuccuacggaaaccUAUUGUUCUGUGGUUGGUUUCGaucuaucguucucguacugcGUGACCUCUACGGAACAAUAGUuuuccaggagauuucccgguuucgacugccgaagcauggaa
..((((..(((((.((((((((((((((..((((.((......((....)).....)).)))).)))))))))))))).)))))))))...((((..((((((.....))))))..))))

Structure
------------------------------au    ac     c              UU    U  aucuau  u 
                                uccu  ggaaa cUAUUGUUCUGUGG  GGUU CG      cg u
                                ||||  ||||| ||||||||||||||  |||| ||      ||  
                                agga  ccuuu GAUAACAAGGCAUC  CCAG Gc      gc c
aagguacgaagccgucagcuuuggcccuuuag    --     U              -U    U  -gucau  u 


Annotation confidence Not enough data
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Genome context
AF243438.1: 142201-142320 [+]
Clustered miRNAs
3 other miRNAs are < 10 kb from mdv1-mir-M8
Name Accession Chromosome Start End Strand Confidence




Disease association
mdv1-mir-M8 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature mdv1-miR-M8-5p

Accession MIMAT0005805
Description Mareks disease virus type 1 mdv1-miR-M8-5p mature miRNA
Sequence 16 - UAUUGUUCUGUGGUUGGUUUCG - 37
Evidence experimental
cloned [2-3], Northern [2], Illumina [4]

Mature mdv1-miR-M8-3p

Accession MIMAT0003929
Description Mareks disease virus type 1 mdv1-miR-M8-3p mature miRNA
Sequence 58 - GUGACCUCUACGGAACAAUAGU - 79
Evidence experimental
cloned [1-3], Northern [1], Illumina [4]

References

  1. PubMed ID: 18256158
    MicroRNA profile of Marek's disease virus-transformed T-cell line MSB-1: predominance of virus-encoded microRNAs
    "Yao Y, Zhao Y, Xu H, Smith LP, Lawrie CH, Watson M, Nair V"
    "J Virol (2008) 82:4007-4015

  2. PubMed ID: 16912324
    Marek's disease virus encodes MicroRNAs that map to meq and the latency-associated transcript
    "Burnside J, Bernberg E, Anderson A, Lu C, Meyers BC, Green PJ, Jain N, Isaacs G, Morgan RW"
    "J Virol (2006) 80:8778-8786

  3. PubMed ID: 18430245
    Deep sequencing of chicken microRNAs
    Burnside J, Ouyang M, Anderson A, Bernberg E, Lu C, Meyers BC, Green PJ, Markis M, Isaacs G, Huang E, Morgan RW
    BMC Genomics (2008) 9:185

  4. PubMed ID: 18842708
    Sequence conservation and differential expression of Marek's disease virus microRNAs
    "Morgan R, Anderson A, Bernberg E, Kamboj S, Huang E, Lagasse G, Isaacs G, Parcells M, Meyers BC, Green PJ, Burnside J"
    "J Virol (2008) 82:12213-12220