Stem-loop mmu-mir-743a

Accession

MI0005207

Symbol

MGI: Mir743

Description

Mus musculus mmu-mir-743a precursor miRNA mir-743

Gene
family

RF04270; mir-743

Literature search

10 open access papers mention mmu-mir-743a
(36 sentences)

Sequence

38122 reads, 2145 reads per million, 43 experiments

cugUAUUCAGAUUGGUGCCUGUCAUguuuauaagaauGAAAGACACCAAGCUGAGUAGAgua
((.(((((((.((((((.((.((((..........)))).)).)))))).))))))).))..

Structure

--  g       A      C  G    guuu 
  cu UAUUCAG UUGGUG CU UCAU    a
  || ||||||| |||||| || ||||     
  gA AUGAGUC AACCAC GA AGua    u
au  G       G      A  A    agaa 

Annotation confidence Medium

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

chrX: 66776757-66776818 [-]

Clustered miRNAs

3 other miRNAs are < 10 kb from mmu-mir-743a

Mature mmu-miR-743a-5p

• Accession: MIMAT0017263
• Description: Mus musculus mmu-miR-743a-5p mature miRNA
• Sequence: 4 - UAUUCAGAUUGGUGCCUGUCAU - 25
• Evidence: experimental ; Illumina [4]

Mature mmu-miR-743a-3p

• Accession: MIMAT0004238
• Description: Mus musculus mmu-miR-743a-3p mature miRNA
• Sequence: 38 - GAAAGACACCAAGCUGAGUAGA - 59
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009