Accession
MI0005416
Symbol
HGNC:
MIR675
Description
Homo sapiens
hsa-mir-675 precursor miRNA mir-675
Gene
family?
family?
RF00897;
mir-675
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR675 is a microRNA encoded by the long non-coding RNA (lncRNA) H19, which plays a role in cellular proliferation [PMC4741653]. In the context of tumor growth, a significant reduction in the proliferation marker Ki67 was observed in tumors where MIR675 was knocked down, indicating that MIR675 may contribute to tumor cell proliferation [PMC4741653]. Specifically, Ki67 positive cells were markedly fewer in MIR675 knockdown tumors compared to controls [PMC4741653]. Despite these findings, it is important to note that the implications of MIR675 and its parent lncRNA H19 have not been explored in heterotopic ossification (HO) patients or animal models of HO formation [PMC9753082]. This gap highlights an area for future research to understand the potential role of MIR675 in HO development and its underlying mechanisms [PMC9753082].
Literature search
106 open access papers mention hsa-mir-675
(931 sentences)
(931 sentences)
Sequence
1153
reads,
141
reads per million, 58 experiments
cccagggucUGGUGCGGAGAGGGCCCACAGUGgacuuggugacgCUGUAUGCCCUCACCGCUCAgccccuggg
(((((((.((((.((((.((((((..((((((..........))))))..)))))).)))))))).)))))))
(((((((.((((.((((.((((((..((((((..........))))))..)))))).)))))))).)))))))
Structure
u U A CC gacu
cccaggg cUGG GCGG GAGGGC ACAGUG u
||||||| |||| |||| |||||| ||||||
ggguccc gACU CGCC CUCCCG UGUCgc g
c - A UA agug
Annotation confidence
High
Do you think this miRNA is real?
Genome context
chr11: 1996759-1996831 [-]
Disease association
hsa-mir-675 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Biological pathways
hsa-mir-675 is involved in one or more biological pathways:
(Source: Reactome)
(Source: Reactome)
Biological reactions
hsa-mir-675 is involved in one or more regulation/signalling events:
(Source: Reactome)
(Source: Reactome)
Database links
Mature hsa-miR-675-5p
| Accession | MIMAT0004284 |
| Description | Homo sapiens hsa-miR-675-5p mature miRNA |
| Sequence | 10 - UGGUGCGGAGAGGGCCCACAGUG - 32 |
| Evidence |
experimental
cloned [1] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-675-3p
| Accession | MIMAT0006790 |
| Description | Homo sapiens hsa-miR-675-3p mature miRNA |
| Sequence | 45 - CUGUAUGCCCUCACCGCUCA - 64 |
| Evidence |
experimental
cloned [2] |
| Database links |
|
| Predicted targets |
|
References
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