Stem-loop mmu-mir-421

Accession

MI0005496

Symbol

MGI: Mir421

Description

Mus musculus mmu-mir-421 precursor miRNA

Gene family

MIPF0000098; mir-95

Literature search

19 open access papers mention mmu-mir-421
(43 sentences)

Sequence

17237 reads, 144 reads per million, 100 experiments

cauuguaggcCUCAUUAAAUGUUUGUUGAAUgaaaaaaugaaucAUCAACAGACAUUAAUUGGGCGCcugcucugu
((..((((((((((...((((((((((((.(((.........)))))))))))))))...)))).))))))..)).

Structure

-  uu      -    UUA            A   aaa 
 ca  guaggc CUCA   AAUGUUUGUUGA Uga   a
 ||  |||||| ||||   |||||||||||| |||   a
 gu  cgucCG GGGU   UUACAGACAACU Acu   u
u  cu      C    UAA            -   aag 

Annotation confidence High

Genome context

chrX: 103572921-103572996 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mmu-mir-421

Mature mmu-miR-421-5p

• Accession: MIMAT0017273
• Description: Mus musculus mmu-miR-421-5p mature miRNA
• Sequence: 11 - CUCAUUAAAUGUUUGUUGAAU - 31
• Evidence: experimental ; Illumina [3]

Mature mmu-miR-421-3p

• Accession: MIMAT0004869
• Description: Mus musculus mmu-miR-421-3p mature miRNA
• Sequence: 45 - AUCAACAGACAUUAAUUGGGCGC - 67
• Evidence: experimental ; cloned [1], Illumina [2-3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009