Stem-loop sequence mmu-mir-466f-2

Accession

MI0005508 (change log)

Symbol

MGI:Mir466f-2

Description

Mus musculus miR-466f-2 stem-loop

Gene family

MIPF0000316; mir-467

Literature search

28 open access papers mention mmu-mir-466f-2
(67 sentences)

Stem-loop

   -aa       -       u     c     --ca           gaa 
5'    ugugugu uuacgug gugug augug    uguguguauau   u
      ||||||| ||||||| ||||| |||||    |||||||||||    
3'    acacaca aauguac cacac uacac    acauacauaug   a
   cac       c       u     a     acac           uau 

Deep sequencing

26245 reads, 3.32e+03 reads per million, 157 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Comments

Landgraf et al. identify several offset sequences which map to the 3' arm of the miR-466f hairpin precursors [1]. One sequence consistent with all three putative hairpin loci is shown here.

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr2: 10468675-10468768 [+]
• Overlapping transcripts:

  sense

  OTTMUST00000026263 ; Sfmbt2-001; intron 10

  ENSMUST00000041105 ; Sfmbt2-001; intron 10

  ENSMUST00000116594 ; Sfmbt2-201; intron 11

Clustered miRNAs

< 10kb from mmu-mir-466f-2

• mmu-mir-466m: chr2: 10466663-10466746 [+]
• mmu-mir-466f-1: chr2: 10466944-10467037 [+]
• mmu-mir-669f: chr2: 10467229-10467349 [+]
• mmu-mir-669e: chr2: 10467495-10467613 [+]
• mmu-mir-669b: chr2: 10467790-10467886 [+]
• mmu-mir-669d: chr2: 10468343-10468463 [+]
• mmu-mir-466f-2: chr2: 10468675-10468768 [+]
• mmu-mir-669l: chr2: 10468971-10469068 [+]
• mmu-mir-669d-2: chr2: 10471644-10471729 [+]
• mmu-mir-466f-3: chr2: 10471953-10472046 [+]
• mmu-mir-297a-2: chr2: 10472254-10472343 [+]
• mmu-mir-466o: chr2: 10472540-10472623 [+]
• mmu-mir-467c: chr2: 10473931-10474027 [+]
• mmu-mir-466b-1: chr2: 10474219-10474300 [+]
• mmu-mir-669a-3: chr2: 10474433-10474541 [+]
• mmu-mir-669k: chr2: 10475300-10475426 [+]
• mmu-mir-467a-1: chr2: 10476346-10476418 [+]
• mmu-mir-466b-8: chr2: 10476628-10476713 [+]
• mmu-mir-669a-1: chr2: 10476853-10476949 [+]
• mmu-mir-669g: chr2: 10477150-10477272 [+]
• mmu-mir-669j: chr2: 10477910-10478030 [+]

Database links

• EntrezGene:Mir466f-2
• MGI:Mir466f-2
• RNAcentral:URS000075DA02_10090
• miRBase Tracker:MI0005508

Mature sequence mmu-miR-466f-5p

• Accession: MIMAT0004881
• Sequence: 11 - uacgugugugugcaugugcaug - 32
• Deep sequencing: 8511 reads, 90 experiments
• Evidence: experimental; cloned [1], Illumina [2]
• Database links:
  • RNAcentral:URS000043F6C5_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-466f-5p
  • miRDB:mmu-miR-466f-5p
  • microrna.org:mmu-miR-466f-5p

Mature sequence mmu-miR-466f-3p

• Accession: MIMAT0004882
• Sequence: 55 - cauacacacacacauacacac - 75
• Deep sequencing: 56401 reads, 165 experiments
• Evidence: experimental; cloned [1], Illumina [2]
• Database links:
  • RNAcentral:URS0000238FCE_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-466f-3p
  • miRDB:mmu-miR-466f-3p
  • microrna.org:mmu-miR-466f-3p

References

1. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
2. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).