Stem-loop mmu-mir-872

Accession

MI0005549

Symbol

MGI: Mir872

Description

Mus musculus mmu-mir-872 precursor miRNA

Gene family

MIPF0000399; mir-872

Literature search

4 open access papers mention mmu-mir-872
(13 sentences)

Sequence

203265 reads, 845 reads per million, 104 experiments

aacuuguuagAAGGUUACUUGUUAGUUCAGGaccucauuacuuucugccUGAACUAUUGCAGUAGCCUCCUaacugguuau
((((.(((((.((((((((.(((((((((((................)))))))))..)))))))))).))))).))))..

Structure

--    u     A        U  --         accucau 
  aacu guuag AGGUUACU GU  UAGUUCAGG       u
  |||| ||||| |||||||| ||  |||||||||        
  uugg caaUC UCCGAUGA CG  AUCAAGUcc       a
ua    u     C        -  UU         gucuuuc 

Annotation confidence High

Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context

chr4: 94665157-94665237 [+]

Mature mmu-miR-872-5p

• Accession: MIMAT0004934
• Description: Mus musculus mmu-miR-872-5p mature miRNA
• Sequence: 11 - AAGGUUACUUGUUAGUUCAGG - 31
• Evidence: experimental ; cloned [2], Illumina [3-4]

Mature mmu-miR-872-3p

• Accession: MIMAT0004935
• Description: Mus musculus mmu-miR-872-3p mature miRNA
• Sequence: 50 - UGAACUAUUGCAGUAGCCUCCU - 71
• Evidence: experimental ; cloned [2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298