miRBase entry: hsa-mir-301b

Stem-loop hsa-mir-301b

Accession

MI0005568

Symbol

HGNC: MIR301B

Description

Homo sapiens hsa-mir-301b precursor miRNA

Literature search

62 open access papers mention hsa-mir-301b
(167 sentences)

Sequence

38694 reads, 203 reads per million, 84 experiments

gccgcagguGCUCUGACGAGGUUGCACUACUgugcucugagaagCAGUGCAAUGAUAUUGUCAAAGCaucugggacca
.((.((((((((.((((((.((((((((.((...........)).))))))))....)))))).))))))))))....

Structure

---g  g        C      ---G        A  gugc 
    cc cagguGCU UGACGA    GUUGCACU CU    u
    || |||||||| ||||||    |||||||| ||    c
    gg gucuaCGA ACUGUU    UAACGUGA ga    u
acca  -        A      AUAG        C  agag

Annotation confidence High

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Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context

chr22: 21652981-21653058 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-301b

Name	Accession	Chromosome	Start	End	Strand	Confidence

Database links

Mature hsa-miR-301b-3p

Accession	MIMAT0004958
Description	Homo sapiens hsa-miR-301b-3p mature miRNA
Sequence	45 - CAGUGCAAUGAUAUUGUCAAAGC - 67
Evidence	experimental cloned [2]
Database links
Predicted targets

Mature hsa-miR-301b-5p

Accession	MIMAT0032026
Description	Homo sapiens hsa-miR-301b-5p mature miRNA
Sequence	10 - GCUCUGACGAGGUUGCACUACU - 31
Evidence	not_experimental
Database links
Predicted targets

References

PubMed ID: 17604727
A mammalian microRNA expression atlas based on small RNA library sequencing
"Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
"Cell (2007) 129:1401-1414

PubMed ID: 16954537
Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
"Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
"Genome Res (2006) 16:1289-1298