miRBase entry: hsv1-mir-H6

Stem-loop hsv1-mir-H6


Accession
MI0008941
Description
Herpes Simplex Virus 1 hsv1-mir-H6 precursor miRNA
Gene family
MIPF0000738; mir-H1


Sequence

cggggggccggagGGUGGAAGGCAGGGGGGUGUAggauggguaucaggacuucCACUUCCCGUCCUUCCAUCCCccguuccccucg
(((((((.(((.((((((((((..((((((((.((..((.....))...))..))))))))..)))))))))).)))..)))))))

Structure
       -c   a          CA        -U  -ga  g 
cgggggg  cgg gGGUGGAAGG  GGGGGGUG  Ag   ug g
|||||||  ||| ||||||||||  ||||||||  ||   || u
gcucccc  gcc CCUACCUUCC  CCCUUCAC  uc   ac a
       uu   C          UG        cu  agg  u 


Annotation confidence Not enough data
Do you think this miRNA is real?

Genome context
Unknown

Database links

Mature hsv1-miR-H6-5p

Accession MIMAT0015281
Description Herpes Simplex Virus 1 hsv1-miR-H6-5p mature miRNA
Sequence 14 - GGUGGAAGGCAGGGGGGUGUA - 34
Evidence experimental
Illumina [3]

Mature hsv1-miR-H6-3p

Accession MIMAT0008404
Description Herpes Simplex Virus 1 hsv1-miR-H6-3p mature miRNA
Sequence 54 - CACUUCCCGUCCUUCCAUCCC - 74
Evidence experimental
454 [1], qRT-PCR [1], Illumina [2-3]

References

  1. PubMed ID: 20181707
    Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2
    "Jurak I, Kramer MF, Mellor JC, van Lint AL, Roth FP, Knipe DM, Coen DM"
    "J Virol (2010) 84:4659-4672

  2. PubMed ID: 18596690
    MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs
    "Umbach JL, Kramer MF, Jurak I, Karnowski HW, Coen DM, Cullen BR"
    "Nature (2008) 454:780-783

  3. PubMed ID: 19656888
    Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal ganglia
    "Umbach JL, Nagel MA, Cohrs RJ, Gilden DH, Cullen BR"
    "J Virol (2009) 83:10677-10683