miRBase entry: bta-mir-2484

Stem-loop bta-mir-2484


Accession
MI0011546
Description
Bos taurus bta-mir-2484 precursor miRNA

Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?

Bta-mir-2484 is a microRNA that has been found to exhibit increased expression in the peripheral blood mononuclear cells (PBMCs) of buffaloes infected with Mycobacterium paratuberculosis [PMC7242893]. It is one of the top three up-regulated miRNAs in these infected buffaloes, along with bta-miR-592 and bta-miR-1247-5p [PMC5766512]. Interestingly, bta-mir-2484 has also been detected in mammary glands infected with Staphylococcus aureus, suggesting a potential association between these two infections [PMC6600136]. It is worth noting that bta-mir-2484 appears to be nearly species-specific and does not have homologs in humans or mice [PMC6600136]. In a study validating the results obtained from RNA sequencing, bta-mir-2484 was one of the six miRNAs selected for examination using RT-qPCR [PMC6600136]. Additionally, it has been found to regulate CYP7A1 along with two other miRNAs (bta-miR-27a-3p and bta-miR-194) and one long non-coding RNA in a grass-fed group [PMC7969984].

Literature search
2 open access papers mention bta-mir-2484
(2 sentences)

Sequence

302 reads, 23 reads per million, 63 experiments
uuaucugaaaauguaugcaggguuauuauaauuaaaaagguGAGCUAUGAUGACUUUGAUUGCAUugaucacauga
((((.(((.((((((..(((((((((((((.(((......)))..)))))))))))))..))))))..))).))))

Structure
    c   -a      ug             -a   aa 
uuau uga  aaugua  caggguuauuaua  uua  a
|||| |||  ||||||  |||||||||||||  |||   
agua acu  uUACGU  GUUUCAGUAGUAU  AGu  a
    c   ag      UA             CG   gg 


Annotation confidence Not enough data
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Genome context
chrX: 20570714-20570789 [-]

Database links

Mature bta-miR-2484

Accession MIMAT0012077
Description Bos taurus bta-miR-2484 mature miRNA
Sequence 42 - GAGCUAUGAUGACUUUGAUUGCAU - 65
Evidence experimental
Illumina [1]

References

  1. PubMed ID: 19633723
    Repertoire of bovine miRNA and miRNA-like small regulatory RNAs expressed upon viral infection
    Glazov EA, Kongsuwan K, Assavalapsakul W, Horwood PF, Mitter N, Mahony TJ
    PLoS One (2009) 4:e6349