miRBase entry: aae-mir-11

Stem-loop aae-mir-11


Accession
MI0013453
Description
Aedes aegypti aae-mir-11 precursor miRNA
Gene family
MIPF0000252; mir-11

Literature search
4 open access papers mention aae-mir-11
(8 sentences)

Sequence

29712 reads, 1495 reads per million, 2 experiments
aacauugaugcgaguagugccgcgcgAGAACUCCGGCUGUGACCUGUGuacacuuuauccaaaucaCAUCACAGUCUGAGUUCUUGCUuggaggcucgucgaucaacuaaugga
....(((((((((((....(((.((((((((((.((((((((..((((................)))))))))))).)))))))))).)))..))))))..)))))........

Structure
----aaca     --      agug   c          C        CC    uacacuu 
        uugau  gcgagu    ccg gcgAGAACUC GGCUGUGA  UGUG       u
        |||||  ||||||    ||| |||||||||| ||||||||  ||||        
        aacua  ugcucg    ggu CGUUCUUGAG CUGACACU  ACac       a
agguaauc     gc      --ga   U          U        --    uaaaccu 


Annotation confidence High
Do you think this miRNA is real?
Comments
This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context
supercont1.744: 321996-322109 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from aae-mir-11
Name Accession Chromosome Start End Strand Confidence




Database links

Mature aae-miR-11-5p

Accession MIMAT0014241
Description Aedes aegypti aae-miR-11-5p mature miRNA
Sequence 27 - AGAACUCCGGCUGUGACCUGUG - 48
Evidence experimental
454 [1], Illumina [2]

Mature aae-miR-11-3p

Accession MIMAT0014242
Description Aedes aegypti aae-miR-11-3p mature miRNA
Sequence 67 - CAUCACAGUCUGAGUUCUUGCU - 88
Evidence experimental
454 [1], Illumina [2]

References

  1. PubMed ID: 19961592
    Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
    Li S, Mead EA, Liang S, Tu Z
    BMC Genomics (2009) 10:581

  2. PubMed ID: 20167119
    Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
    Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
    BMC Genomics (2010) 11:119