Stem-loop sequence hsa-mir-451b

Accession

MI0017360 (change log)

Symbol

HGNC:MIR451B

Description

Homo sapiens miR-451b stem-loop

Gene family

MIPF0000148; mir-451

Literature search

242 open access papers mention hsa-mir-451b
(1167 sentences)

Stem-loop

   u   u  a     ag    a           aa 
5'  ggg au gcaag  aacc uuaccauuacu  a
    ||| || |||||  |||| |||||||||||   
3'  ccc ua cguuc  uugg aaugguaauga  c
   a   u  c     cu    c           cu 

Deep sequencing

720 reads, 0 reads per million, 18 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr17: 28861371-28861438 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000443628 ; ALOX12P1-001; intron 3

  ENST00000579299 ; ALOX12P1-001; intron 3

Clustered miRNAs

< 10kb from hsa-mir-451b

• hsa-mir-451a: chr17: 28861369-28861440 [-]
• hsa-mir-451b: chr17: 28861371-28861438 [+]
• hsa-mir-144: chr17: 28861533-28861618 [-]
• hsa-mir-4732: chr17: 28861655-28861730 [-]

Database links

• EntrezGene:MIR451B
• HGNC:MIR451B
• miRBase Tracker:MI0017360

Mature sequence hsa-miR-451b

• Accession: MIMAT0019840
• Sequence: 7 - uagcaagagaaccauuaccauu - 28
• Deep sequencing: 715 reads, 26 experiments
• Evidence: experimental; Illumina [1]
• Predicted targets:
  • TargetMiner:hsa-miR-451b
  • TargetScanVert:hsa-miR-451b
  • miRDB:hsa-miR-451b

References

1. PMID:21199797 "Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene" Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C Cancer Res. 71:78-86(2011).