Stem-loop sequence hsa-mir-25

Accession

MI0000082 (change log)

Symbol

HGNC:MIR25

Description

Homo sapiens miR-25 stem-loop

Gene family

MIPF0000013; mir-25

Literature search

252 open access papers mention hsa-mir-25
(914 sentences)

Stem-loop

       a ug   ag    g     uu g     u   --  ac 
5' ggcc g  uug  aggc gagac  g gcaau gcu  gg  g
   |||| |  |||  |||| |||||  | ||||| |||  ||  c
3' ccgg c  gac  ucug cucug  c cguua cgg  cc  u
       c gu   ag    g     uu a     -   gu  cg 

Deep sequencing

1278112 reads, 3.12e+03 reads per million, 159 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr7: 100093560-100093643 [-]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-25

• hsa-mir-106b: chr7: 100093993-100094074 [-]
• hsa-mir-93: chr7: 100093768-100093847 [-]
• hsa-mir-25: chr7: 100093560-100093643 [-]

Database links

• EntrezGene:MIR25
• HGNC:MIR25
• RNAcentral:URS00000C85B2_9606
• miRBase Tracker:MI0000082

Mature sequence hsa-miR-25-5p

• Accession: MIMAT0004498
• Previous IDs: hsa-miR-25*
• Sequence: 14 - aggcggagacuugggcaauug - 34
• Deep sequencing: 68019 reads, 141 experiments
• Evidence: experimental; cloned [3]
• Database links:
  • RNAcentral:URS00001A9746_9606
• Predicted targets:
  • TargetMiner:hsa-miR-25-5p
  • TargetScanVert:hsa-miR-25-5p
  • miRDB:hsa-miR-25-5p
  • microrna.org:hsa-miR-25-5p

Mature sequence hsa-miR-25-3p

• Accession: MIMAT0000081
• Previous IDs: hsa-miR-25
• Sequence: 52 - cauugcacuugucucggucuga - 73
• Deep sequencing: 1210086 reads, 159 experiments
• Evidence: experimental; cloned [1-4], Northern [1]
• Database links:
  • RNAcentral:URS00004F9744_9606
• Predicted targets:
  • TargetMiner:hsa-miR-25-3p
  • TargetScanVert:hsa-miR-25-3p
  • miRDB:hsa-miR-25-3p
  • microrna.org:hsa-miR-25-3p

References

1. PMID:11679670 "Identification of novel genes coding for small expressed RNAs" Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T Science. 294:853-858(2001).
2. PMID:15325244 "Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells" Kasashima K, Nakamura Y, Kozu T Biochem Biophys Res Commun. 322:403-410(2004).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).