Stem-loop sequence mmu-mir-141

Accession

MI0000166 (change log)

Symbol

MGI:Mir141

Description

Mus musculus miR-141 stem-loop

Gene family

MIPF0000019; mir-8

Literature search

128 open access papers mention mmu-mir-141
(1109 sentences)

Stem-loop

      u       --    u          au    gaa 
5' ggg ccaucuu  ccag gcaguguugg  gguu   g
   ||| |||||||  |||| ||||||||||  ||||   u
3' ccc gguagaa  gguc ugucacaauc  ucga   a
      -       au    -          -c    agu 

Deep sequencing

191453 reads, 933 reads per million, 99 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr6: 124717914-124717985 [-]
• Overlapping transcripts:

  sense

  OTTMUST00000067268 ; RP24-297C1.9-001; intron 1

  ENSMUST00000143765 ; Gm15884-001; intron 1

Clustered miRNAs

< 10kb from mmu-mir-141

• mmu-mir-200c: chr6: 124718322-124718390 [-]
• mmu-mir-141: chr6: 124717914-124717985 [-]

Database links

• EntrezGene:Mir141
• MGI:Mir141
• RNAcentral:URS000075EB16_10090
• miRBase Tracker:MI0000166

Mature sequence mmu-miR-141-5p

• Accession: MIMAT0004533
• Previous IDs: mmu-miR-141*
• Sequence: 6 - caucuuccagugcaguguugga - 27
• Deep sequencing: 1032 reads, 57 experiments
• Evidence: experimental; cloned [4], Illumina [5-6]
• Database links:
  • RNAcentral:URS000043B721_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-141-5p
  • miRDB:mmu-miR-141-5p
  • microrna.org:mmu-miR-141-5p

Mature sequence mmu-miR-141-3p

• Accession: MIMAT0000153
• Previous IDs: mmu-miR-141
• Sequence: 48 - uaacacugucugguaaagaugg - 69
• Deep sequencing: 190380 reads, 99 experiments
• Evidence: experimental; cloned [1,3-4], Illumina [5-6]
• Database links:
  • RNAcentral:URS000003E1A9_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-141-3p
  • miRDB:mmu-miR-141-3p
  • microrna.org:mmu-miR-141-3p

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
3. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
5. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
6. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).