Stem-loop sequence mmu-mir-200a

Accession

MI0000554 (change log)

Symbol

MGI:Mir200a

Description

Mus musculus miR-200a stem-loop

Gene family

MIPF0000019; mir-8

Literature search

294 open access papers mention mmu-mir-200a
(1890 sentences)

Stem-loop

   c    - c   g        -             c    uu  uu 
5'  uggg c ucu ugggcauc uuaccggacagug ugga  uc  g
    |||| | ||| |||||||| ||||||||||||| ||||  ||  g
3'  accc g gga acuuguag aauggucugucac aucu  ag  c
   c    a u   a        c             a    -c  uu 

Deep sequencing

260292 reads, 956 reads per million, 99 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr4: 156054896-156054985 [-]
• Overlapping transcripts:

  sense

  OTTMUST00000117417 ; Ttll10-005; intron 1

  OTTMUST00000025771 ; Ttll10-001; intron 1

  OTTMUST00000031955 ; RP23-118E21.8-001; intron 1

  ENSMUST00000184348 ; Ttll10-005; intron 1

  ENSMUST00000097731 ; Ttll10-001; intron 1

  ENSMUST00000138361 ; Gm13648-001; intron 1

Clustered miRNAs

< 10kb from mmu-mir-200a

• mmu-mir-200b: chr4: 156055681-156055750 [-]
• mmu-mir-200a: chr4: 156054896-156054985 [-]
• mmu-mir-429: chr4: 156053905-156053987 [-]

Database links

• EntrezGene:Mirn200a
• MGI:Mir200a
• RNAcentral:URS000075B1D6_10090
• miRBase Tracker:MI0000554

Mature sequence mmu-miR-200a-5p

• Accession: MIMAT0004619
• Previous IDs: mmu-miR-200a*
• Sequence: 16 - caucuuaccggacagugcugga - 37
• Deep sequencing: 3965 reads, 71 experiments
• Evidence: experimental; cloned [2], Illumina [3-4]
• Database links:
  • RNAcentral:URS000023B77E_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-200a-5p
  • miRDB:mmu-miR-200a-5p
  • microrna.org:mmu-miR-200a-5p

Mature sequence mmu-miR-200a-3p

• Accession: MIMAT0000519
• Previous IDs: mmu-miR-200a
• Sequence: 54 - uaacacugucugguaacgaugu - 75
• Deep sequencing: 256138 reads, 99 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS000008DA94_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-200a-3p
  • miRDB:mmu-miR-200a-3p
  • microrna.org:mmu-miR-200a-3p

References

1. PMID:12554859 "New microRNAs from mouse and human" Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T RNA. 9:175-179(2003).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).