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13 publications mentioning rno-mir-298

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-298. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 29
Microarray data revealed that several microRNAs were dysregulated in Cs1-ko mice (S1 Table), including miR301a, which was maximally downregulated, whereas, miR-298 was highly upregulated in Cs1-ko mouse hearts (schematically depicted in Fig 2A). [score:8]
MiR-301a was identified the most downregulated microRNA, whereas, miR-298 was highly upregulated (N = 4 each), which was confirmed in independent cohort by quantitative real-time PCR for miR-301a (B), and miR-298 (C) (N = 5 (WT), and 6 (Cs1-ko)). [score:7]
We further validated the expression of miR-301a and miR-298 by quantitative real-time PCR (qPCR) in independent set of mouse cohort to confirm its downregulation (Fig 2B and 2C). [score:6]
Few of the highly upregulated microRNAs were: miR-79, miR-183, miR-206, miR-207, miR-296-3p, miR-298, miR-380-5p, miR-433, miR-449b, miR-705, miR-761 (S1 Table). [score:4]
MiR-206 and miR-298 are previously shown to be upregulated in rat mo del of post-infarction heart failure [50]. [score:4]
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2
[+] score: 26
Hypoxia alone did significantly upregulate miR-298 expression by 50% at 10 days while DOR treatment returned the levels to baseline. [score:6]
Neurexophilin, a ligand for neurexin, is one of the predicted targets of the hypoxia -upregulated miR-298. [score:6]
In the presence of UFP-512, miR-298 showed a hypoxia -induced downregulation that was lost after 10 days of hypoxia. [score:4]
Prolonged hypoxia (10 days) significantly increased the level of miR-298, suggesting a downregulation of Neurexophilin. [score:4]
Relative miRNA expression levels of miR-298, miR-324-3p, and miR-20b-5p in the kidney following either 5 or 10 days of hypoxia as determined by quantitative RT-PCR. [score:3]
The application of DOR agonist attenuated these changes in miR-298 expression. [score:3]
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3
[+] score: 19
MiR-21, miR-31 and miR-488 are down-regulated, while miR-153, miR-135b, miR-135a and miR-298 are up-regulated in secretory-stage enamel formation compared to maturation-stage. [score:6]
In contrast, as seen in the in situ slides, there was a decrease in the expression levels of miR-153, miR-135b, miR-135a and miR-298 from secretory-stage to maturation-stage tooth development (Figure  6K-R). [score:4]
Seven differentially expressed miRNAs (miR-21, miR-31, miR-488, miR-153, miR-135b, miR-135a and miR298) in secretory- and/or maturation-stage enamel organs were confirmed by in situ hybridization. [score:3]
The expression patterns of seven selected miRNAs (miR-21, miR-31, miR-488, miR-153, miR-135b, miR-135a and miR-298) were examined (Figure  6E-R). [score:3]
This trend of expression correlates well with the miRNA qPCR array data (i. e., miR-153, miR-135b, miR-135a and miR-298 changed by -3.7, -12.4, -8.9 and -4.3 fold, respectively) (Additional file 1). [score:3]
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4
[+] score: 15
Comparable to miR-298, hypoxia and DOR activation also downregulated miR-370 and miR-363* expression after 1-day treatment. [score:6]
Upregulation of miR-298 in the brain and blood has been reported in ischemia, hemorrhage and kainate seizures [27]. [score:4]
Relative miRNA expression levels of miR-298, -466b, -101b and -186 in the rat cortex following 1, 5 or 10 days of hypoxia or UFP-512 treatment. [score:3]
Individually, hypoxia -induced and DOR -mediated effects on miRNAs miR-298 and miR-466b resolve at the same rate. [score:1]
In contrast, the cortex in our mo del produces both a hypoxia- and a DOR -mediated loss of miR-298 after 1-day hypoxia. [score:1]
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5
[+] score: 9
Up-regulation of miR-298 was previously reported in both, brain and blood, after ischemic stroke [62], while up-regulation of miR-873 was reported after onset of focal cerebral ischemia in mice [63]. [score:7]
For example, the top three miRNA-hubs in the early IR-injury regulatory network were rno-miR-495, rno-miR-214 and rno-miR-298, whereas rno-miR-873, rno-miR-223 and rno-miR-185 were hubs observed at the late phase post-IR injury. [score:2]
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6
[+] score: 9
Among them, 12 miRNAs (rno-miR-10b-5p, rno-miR-122-5p, rno-miR-184, rno-miR-1843-5p, rno-miR-196c-5p, rno-miR-199a-5p, rno-miR-202-5p, rno-miR-206-3p, rno-miR-208b-5p, rno-miR-224-5p, rno-miR-298-5p and rno-miR-31a-5p) were significantly upregulated(p<0.01, fold-change >1) compared to the control group and only rno-miR-208a-3p were significantly downregulated (p<0.01, fold-change <-1) (Fig 3). [score:6]
Meanwhile, rno-miR-10b-5p, rno-miR-184, rno-miR-1843-5p, rno-miR-196c-5p, rno-miR-202-5p, rno-miR-206-3p, rno-miR-224-5p, rno-miR-298-5p and rno-miR-31a-5p were reported for the first time to be differentially expressed in HF tissue. [score:3]
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7
[+] score: 6
One of the miRNAs displaying the greatest decrease in expression between ages, miR-298, also targets the BACE1 mRNA (Boissonneault et al. 2009), suggesting complementary roles between miR-298 and miR-29a/b in regulating this protein. [score:6]
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8
[+] score: 6
A number of miRNAs are expressed at high intensities throughout the perinatal period, but are not regulated from E20 to P2 (listed with decreasing expression level: miR-298, -494, -292-5p, -503, -290, -320, let-7c, -327, -185, let-7b and let-7a). [score:6]
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9
[+] score: 3
Thus, a BlAST search was performed against the Sanger miRbase to determine identified miRNAs with sequence similar to that of mil-HongrES2; ron-mir-298 was the only one found to have about 50% homology with mil-HongrES2 in sequence and a very low expression ratio (about 10 [−4]) compared with the mir-29a signal in miRNA chips (data not shown) in rat epididymis (Figure 3D). [score:2]
Hence, the ∼23-nt band could not possibly be generated because of cross hybridization to other small RNAs, including the ron-mir-298, under high stringent hybridization conditions at 65°C with LNA probes having less than 50% sequence complementary. [score:1]
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10
[+] score: 3
2014.00002 45 Boissonneault V, Plante I, Rivest S, Provost P. MicroRNA-298 and MicroRNA-328 Regulate Expression of Mouse beta-Amyloid Precursor Protein-converting Enzyme 1. J Biol Chem. [score:3]
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11
[+] score: 2
Other miRNAs from this paper: hsa-let-7a-2, hsa-let-7c, hsa-let-7e, hsa-mir-15a, hsa-mir-16-1, hsa-mir-21, hsa-mir-22, hsa-mir-23a, hsa-mir-24-2, hsa-mir-100, hsa-mir-29b-2, mmu-let-7i, mmu-mir-99b, mmu-mir-125a, mmu-mir-130a, mmu-mir-142a, mmu-mir-144, mmu-mir-155, mmu-mir-183, hsa-mir-196a-1, mmu-mir-199a-1, hsa-mir-199a-1, mmu-mir-200b, hsa-mir-148a, mmu-mir-143, hsa-mir-181c, hsa-mir-183, hsa-mir-199a-2, hsa-mir-199b, hsa-mir-181a-1, hsa-mir-200b, mmu-mir-298, mmu-mir-34b, hsa-let-7i, hsa-mir-124-1, hsa-mir-124-2, hsa-mir-130a, hsa-mir-142, hsa-mir-143, hsa-mir-144, hsa-mir-125a, mmu-mir-148a, mmu-mir-196a-1, mmu-let-7a-2, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-mir-15a, mmu-mir-16-1, mmu-mir-21a, mmu-mir-22, mmu-mir-23a, mmu-mir-24-2, rno-mir-148b, mmu-mir-148b, hsa-mir-200c, hsa-mir-155, mmu-mir-100, mmu-mir-200c, mmu-mir-181a-1, mmu-mir-29b-2, mmu-mir-199a-2, mmu-mir-199b, mmu-mir-124-1, mmu-mir-124-2, mmu-mir-181c, hsa-mir-34b, hsa-mir-99b, hsa-mir-374a, hsa-mir-148b, rno-let-7a-2, rno-let-7c-1, rno-let-7c-2, rno-let-7e, rno-let-7i, rno-mir-21, rno-mir-22, rno-mir-23a, rno-mir-24-2, rno-mir-29b-2, rno-mir-34b, rno-mir-99b, rno-mir-100, rno-mir-124-1, rno-mir-124-2, rno-mir-125a, rno-mir-130a, rno-mir-142, rno-mir-143, rno-mir-144, rno-mir-181c, rno-mir-183, rno-mir-199a, rno-mir-200c, rno-mir-200b, rno-mir-181a-1, hsa-mir-193b, hsa-mir-497, hsa-mir-568, hsa-mir-572, hsa-mir-596, hsa-mir-612, rno-mir-664-1, rno-mir-664-2, rno-mir-497, mmu-mir-374b, mmu-mir-497a, mmu-mir-193b, mmu-mir-466b-1, mmu-mir-466b-2, mmu-mir-568, hsa-mir-298, hsa-mir-374b, rno-mir-466b-1, rno-mir-466b-2, hsa-mir-664a, mmu-mir-664, rno-mir-568, hsa-mir-664b, mmu-mir-21b, mmu-mir-21c, rno-mir-155, mmu-mir-142b, mmu-mir-497b, rno-mir-148a, rno-mir-15a, rno-mir-193b
Cluster Mapped ESTs Mapped cDNAs mir-497~195 Human: CR737132, DB266639, DA2895925, BI752321, AA631714 Human: AK098506.1 Rat: CV105515 mir-144-451 Human: R28106 Mouse: AK158085.1 Rat: AW919398, BF2869095, AI008234 mir-99b~let-7e~mir-125a Human: DB340912 Human: AK125996 mir-143~145 Human: BM702257 mir-181a-1~181b-1 Human: DA528985, BX355821 Mouse: BE332980, CA874578 mir-29b-2~29c Human: BF089238 Mouse: AK081202, BC058715 mir-298~296 Human: W37080 mir-183~96~182 Human: CV424506 mir-181c~181d Human: AI801869, CB961518, CB991710, BU729805, CB996698, BM702754 Mouse: CJ191375 mir-100~let-7a-2 Human: DA545600, DA579531, DA474693, DA558986, DA600978 Human: AK091713 Mouse: BB657503, BM936455 Rat: BF412891, BF412890, BF412889, BF412895 Mouse: AK084170 mir-374b~421 Human: DA706043, DA721080 Human: AK125301 Rat: BF559199, BI274699 Mouse: BC027389, AK035525, BC076616, AK085125 mir-34b~34c Human: BC021736 mir-15a-16-1 Human: BG612167, BU932403, BG613187, BG500819 Human: BC022349, BC022282, BC070292, BC026275, BC055417, AF264787 Mouse: AI789372, BY718835 Mouse: AK134888, AF380423, AF380425, AK080165 mir-193b~365-1 Human: BX108536 hsa-mir-200c~141 Human: AI969882, AI695443, AA863395, BM855863.1, AA863389 mir-374a~545 Human: DA685273, AL698517, DA246751, DA755860, CF994086, DA932670, DA182706 Human: AK057701 Figure 2 Predicted pri-miRNAs, their lengths, and features that support the pri-miRNA prediction. [score:1]
Cluster Mapped ESTs Mapped cDNAs mir-497~195 Human: CR737132, DB266639, DA2895925, BI752321, AA631714 Human: AK098506.1 Rat: CV105515 mir-144-451 Human: R28106 Mouse: AK158085.1 Rat: AW919398, BF2869095, AI008234 mir-99b~let-7e~mir-125a Human: DB340912 Human: AK125996 mir-143~145 Human: BM702257 mir-181a-1~181b-1 Human: DA528985, BX355821 Mouse: BE332980, CA874578 mir-29b-2~29c Human: BF089238 Mouse: AK081202, BC058715 mir-298~296 Human: W37080 mir-183~96~182 Human: CV424506 mir-181c~181d Human: AI801869, CB961518, CB991710, BU729805, CB996698, BM702754 Mouse: CJ191375 mir-100~let-7a-2 Human: DA545600, DA579531, DA474693, DA558986, DA600978 Human: AK091713 Mouse: BB657503, BM936455 Rat: BF412891, BF412890, BF412889, BF412895 Mouse: AK084170 mir-374b~421 Human: DA706043, DA721080 Human: AK125301 Rat: BF559199, BI274699 Mouse: BC027389, AK035525, BC076616, AK085125 mir-34b~34c Human: BC021736 mir-15a-16-1 Human: BG612167, BU932403, BG613187, BG500819 Human: BC022349, BC022282, BC070292, BC026275, BC055417, AF264787 Mouse: AI789372, BY718835 Mouse: AK134888, AF380423, AF380425, AK080165 mir-193b~365-1 Human: BX108536 hsa-mir-200c~141 Human: AI969882, AI695443, AA863395, BM855863.1, AA863389 mir-374a~545 Human: DA685273, AL698517, DA246751, DA755860, CF994086, DA932670, DA182706 Human: AK057701 Figure 2 Predicted pri-miRNAs, their lengths, and features that support the pri-miRNA prediction. [score:1]
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12
[+] score: 1
miRNAs miR-298* and 532-3p in comparison P8 vs P14.4 and miR-193-3p in comparison P14.4 vs P21.4 are out of plots. [score:1]
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13
[+] score: 1
They showed that miR-298 and miR-245 increased in the blood injected ICH mo del, and that there was a miR-107, miR-200b and miR-331-5p increment in the thrombin injection mo del [8]. [score:1]
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