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1 publications mentioning dps-mir-1

Open access articles that are associated with the species Drosophila pseudoobscura and mention the gene name mir-1. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 16
Indeed, decreased mRNA levels (in human HeLa cells) were observed for dozens of genes upon transfection of two distinct miRNAs, miR-1 and miR-124; it was also shown that the 3′ untranslated regions (UTRs) of these down-regulated mRNAs have significant complementarity to the 5′ extremity of the transfected miRNAs. [score:6]
In fact, most of the mRNAs encoding cytosolic sector subunits (A, B, D, E, F, and H) of a C. elegans vacuolar H [+]-ATPase contain a conserved target site for miR-1, suggesting a miRNA -mediated regulation of this proton-pumping complex. [score:4]
For example, we found that the predicted target set of C. elegans miR-1 (197 genes having a conserved ACAUUCC or CAUUCCA in their 3′UTRs) contains many genes involved in proton transport (p < 10 [−10]) and ATPase activity (p < 10 [−9]). [score:3]
Similarly, the target sites for miR-2/43 and miR-1 are coconserved in 12 genes (p < 10 [−6]). [score:3]
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