miRNA Search Results

sort by 4 publications mentioning rno-mir-543 Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-543. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.
1	[+] score: 23 Other miRNAs from this paper: mmu-mir-9-2, mmu-mir-137, mmu-mir-145a, mmu-mir-152, mmu-mir-155, mmu-mir-181a-2, mmu-mir-182, mmu-mir-193a, mmu-mir-203, mmu-mir-143, mmu-mir-301a, mmu-mir-130b, mmu-mir-19b-2, mmu-mir-148a, mmu-let-7b, mmu-mir-29a, mmu-mir-29c, mmu-mir-31, rno-mir-301a, rno-mir-324, mmu-mir-324, rno-mir-351-1, mmu-mir-351, mmu-mir-107, mmu-mir-200c, mmu-mir-181a-1, mmu-mir-218-1, mmu-mir-218-2, mmu-mir-222, mmu-mir-19b-1, mmu-mir-9-1, mmu-mir-9-3, mmu-mir-381, mmu-mir-382, mmu-mir-133b, rno-let-7b, rno-mir-9a-1, rno-mir-9a-3, rno-mir-9a-2, rno-mir-19b-1, rno-mir-19b-2, rno-mir-29a, rno-mir-29c-1, rno-mir-31a, rno-mir-107, rno-mir-130b, rno-mir-137, rno-mir-143, rno-mir-145, rno-mir-152, rno-mir-181a-2, rno-mir-193a, rno-mir-200c, rno-mir-203a, rno-mir-181a-1, rno-mir-218a-2, rno-mir-218a-1, rno-mir-222, mmu-mir-489, rno-mir-489, rno-mir-133b, mmu-mir-543, mmu-mir-494, mmu-mir-369, mmu-mir-20b, rno-mir-494, rno-mir-381, rno-mir-382, rno-mir-369, rno-mir-20b, mmu-mir-495, mmu-mir-455, mmu-mir-193b, rno-mir-182, rno-mir-455, rno-mir-495, rno-mir-203b, rno-mir-31b, rno-mir-9b-3, rno-mir-218b, rno-mir-9b-1, rno-mir-9b-2, mmu-mir-145b, rno-mir-155, rno-mir-148a, rno-mir-193b, rno-mir-29c-2, rno-mir-351-2, mmu-mir-9b-2, mmu-mir-9b-1, mmu-mir-9b-3 The current data suggest that multiple miRNAs, including miR-9, miR-137, miR-155, miR-301a, miR455, and miR-543 (Figure 7A and Figure 8A), regulate c-Maf expression through its 3′-UTR. [score:4] We conclude that miR-9, miR-137, miR-200c, miR-381, miR-455, miR-495, and miR-543 represent an FGF2 -dependent system of multiple miRNAs that target specific genes operating in pathways and processes related to the lens differentiation (via c-Maf, Med1/PBP, N-myc, and Nfat5), miRNA-regulated RNA processing (via Cpsf6 and Tnrc6b) and nuclear/chromatin -based processes (via Med1/PBP, As1l, and Kdm5b/Jarid1b/Plu1). [score:4] We found that seven miRNAs, including miR-9, miR-137, miR-200c, miR-381, miR-455, miR-495, and miR-543, target at least two “early” genes examined (i. e., c-Maf, N-Myc, and Nfib). [score:3] Three miRNAs from this cluster, including miR-495, miR-543, and miR-381, represent a group of most highly connected miRNAs in this system (Figure 6A) and regulate together multiple genes known to regulate lens fiber cell differentiation, including c-Maf (Figure 7 and Figure 10). [score:3] This gross analysis is consistent with our findings of genes regulated by miR-495, miR-543, and miR-381 in lens that belong to these similar categories (Figure 5). [score:2] We predict that several important regulatory genes of lens fiber cell differentiation, including c-Maf, Kdm5b/Jarid1b, Med1/PBP, Nfat5/OREBP, and N-Myc, are connected by multiple shared miRNAs, with four of them, including miR-381, miR-495, miR-382, and miR-543, encoded by a miRNA cluster on rat chromosome 6, a syntenic region with mouse chromosome 12, and human 14q32.2 imprinted regions. [score:2] The miR-495 and miR-543 are neighbors, and miR-381 is located ~12.7 kb from miR-495. [score:1] Seven miRNAs, including miR-9, miR-137, miR-200c, miR-381, miR-455, miR-495, and miR-543, and connections to specific functional groups of genes are shown. [score:1] The miR-381, miR-495, miR-543, and miR-382 form a miRNA-gene cluster on rat chromosome 6q32. [score:1] The most connected miRNA identified here through the 12 top-ranking transcripts, including miR-495, miR-200c, miR-543, miR-381, and miR-9 (Figure 6A), retained their high-connectivity positions as identified by independent analysis shown earlier in Figure 6A. [score:1] Notably, miR-381, miR-495, and miR-543 form a miRNA-gene cluster on rat chromosome 6, and its syntenic regions on mouse and human chromosome 12 and 14, respectively (Sewer et al. 2005). [score:1] [1 to 20 of 11 sentences]
2	[+] score: 12 Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-16-1, hsa-mir-17, hsa-mir-21, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-25, hsa-mir-26a-1, hsa-mir-26b, hsa-mir-30a, hsa-mir-31, hsa-mir-96, hsa-mir-99a, hsa-mir-16-2, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-182, hsa-mir-183, hsa-mir-211, hsa-mir-217, hsa-mir-218-1, hsa-mir-218-2, hsa-mir-221, hsa-mir-222, hsa-let-7g, hsa-let-7i, hsa-mir-15b, hsa-mir-23b, hsa-mir-30b, hsa-mir-125b-1, hsa-mir-132, hsa-mir-143, hsa-mir-145, hsa-mir-191, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-184, hsa-mir-190a, hsa-mir-195, rno-mir-322-1, rno-let-7d, rno-mir-335, rno-mir-342, rno-mir-135b, hsa-mir-30c-1, hsa-mir-299, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-379, hsa-mir-382, hsa-mir-342, hsa-mir-135b, hsa-mir-335, rno-let-7a-1, rno-let-7a-2, rno-let-7b, rno-let-7c-1, rno-let-7c-2, rno-let-7e, rno-let-7f-1, rno-let-7f-2, rno-let-7i, rno-mir-15b, rno-mir-16, rno-mir-17-1, rno-mir-21, rno-mir-23a, rno-mir-23b, rno-mir-24-1, rno-mir-24-2, rno-mir-25, rno-mir-26a, rno-mir-26b, rno-mir-30c-1, rno-mir-30e, rno-mir-30b, rno-mir-30d, rno-mir-30a, rno-mir-30c-2, rno-mir-31a, rno-mir-96, rno-mir-99a, rno-mir-125a, rno-mir-125b-1, rno-mir-125b-2, rno-mir-126a, rno-mir-132, rno-mir-143, rno-mir-145, rno-mir-183, rno-mir-184, rno-mir-190a-1, rno-mir-191a, rno-mir-195, rno-mir-211, rno-mir-217, rno-mir-218a-2, rno-mir-218a-1, rno-mir-221, rno-mir-222, rno-mir-299a, hsa-mir-384, hsa-mir-20b, hsa-mir-409, hsa-mir-412, hsa-mir-489, hsa-mir-494, rno-mir-489, rno-mir-412, rno-mir-542-1, rno-mir-379, rno-mir-494, rno-mir-382, rno-mir-409a, rno-mir-20b, hsa-mir-542, hsa-mir-770, hsa-mir-190b, hsa-mir-543, rno-mir-466c, rno-mir-17-2, rno-mir-182, rno-mir-190b, rno-mir-384, rno-mir-673, rno-mir-674, rno-mir-770, rno-mir-31b, rno-mir-191b, rno-mir-299b, rno-mir-218b, rno-mir-126b, rno-mir-409b, rno-let-7g, rno-mir-190a-2, rno-mir-322-2, rno-mir-542-2, rno-mir-542-3 Among the miRNAs examined, 79 miRNAs (24%) responded to the hyperandrogenic condition and interestingly, 80% of which were upregulated compared to the control group supporting the notion that hyperandrogenic condition down-regulates androgen receptors in the granulosa cells [35] which could be mediated by these upregulated miRNAs (rno-miR-379, rno-let-7d, rno-miR-24, rno-miR-673, rno-miR-26b, rno-miR-335, rno-miR-382, rno-miR-412, rno-miR-99a, rno-miR-543, rno-miR-674-3p, rno-miR-409-3p). [score:9] A list of differentially expressed miRNAs (Fold change ≥ 2 and their corresponding P value) is presented in Figure 4. Beside this group, miRNAs which were also highly abundant in DHT -treated ovaries are rno-miR-221, rno-miR-222, rno-miR-25, rno-miR-26b, rno-miR-379, rno-let-7d, rno-miR-24, rno-miR-673, rno-miR-26b, rno-miR-335, rno-miR-382, rno-miR-412, rno-miR-99a, rno-miR-543, rno-miR-674-3p, rno-miR-409-3p. [score:3] [1 to 20 of 2 sentences]
3	[+] score: 6 Other miRNAs from this paper: rno-mir-323, rno-mir-96, rno-mir-125a, rno-mir-127, rno-mir-141, rno-mir-145, rno-mir-146a, rno-mir-183, rno-mir-200c, rno-mir-200a, rno-mir-200b, rno-mir-429, rno-mir-409a, rno-mir-547, rno-mir-3585, rno-mir-155 All these miRNAs except miR-543-5p also displayed significant changes of expression (padj-value =< 5.2E-02) between groups C-C and HF-HF (Table 4). [score:3] Remarkably all these miRNAs except miR-543-5p (shaded miRNA) also displayed significant changes of expression (padj-value = < 5.2E-02) between groups C-C and HF-HF, thus defining a subset of miRNAs repeatedly impacted by the perinatal unbalanced environment. [score:3] [1 to 20 of 2 sentences]
4	[+] score: 3 Other miRNAs from this paper: rno-mir-216a, rno-mir-291a, rno-mir-760, rno-mir-490, rno-mir-291b In the LHb we found reduced expression in LH animals of miR-543 relative to controls (Fig 4B). [score:3] [1 to 20 of 1 sentences]

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4 publications mentioning rno-mir-543

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-543. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 23

Other miRNAs from this paper: mmu-mir-9-2, mmu-mir-137, mmu-mir-145a, mmu-mir-152, mmu-mir-155, mmu-mir-181a-2, mmu-mir-182, mmu-mir-193a, mmu-mir-203, mmu-mir-143, mmu-mir-301a, mmu-mir-130b, mmu-mir-19b-2, mmu-mir-148a, mmu-let-7b, mmu-mir-29a, mmu-mir-29c, mmu-mir-31, rno-mir-301a, rno-mir-324, mmu-mir-324, rno-mir-351-1, mmu-mir-351, mmu-mir-107, mmu-mir-200c, mmu-mir-181a-1, mmu-mir-218-1, mmu-mir-218-2, mmu-mir-222, mmu-mir-19b-1, mmu-mir-9-1, mmu-mir-9-3, mmu-mir-381, mmu-mir-382, mmu-mir-133b, rno-let-7b, rno-mir-9a-1, rno-mir-9a-3, rno-mir-9a-2, rno-mir-19b-1, rno-mir-19b-2, rno-mir-29a, rno-mir-29c-1, rno-mir-31a, rno-mir-107, rno-mir-130b, rno-mir-137, rno-mir-143, rno-mir-145, rno-mir-152, rno-mir-181a-2, rno-mir-193a, rno-mir-200c, rno-mir-203a, rno-mir-181a-1, rno-mir-218a-2, rno-mir-218a-1, rno-mir-222, mmu-mir-489, rno-mir-489, rno-mir-133b, mmu-mir-543, mmu-mir-494, mmu-mir-369, mmu-mir-20b, rno-mir-494, rno-mir-381, rno-mir-382, rno-mir-369, rno-mir-20b, mmu-mir-495, mmu-mir-455, mmu-mir-193b, rno-mir-182, rno-mir-455, rno-mir-495, rno-mir-203b, rno-mir-31b, rno-mir-9b-3, rno-mir-218b, rno-mir-9b-1, rno-mir-9b-2, mmu-mir-145b, rno-mir-155, rno-mir-148a, rno-mir-193b, rno-mir-29c-2, rno-mir-351-2, mmu-mir-9b-2, mmu-mir-9b-1, mmu-mir-9b-3

The current data suggest that multiple miRNAs, including miR-9, miR-137, miR-155, miR-301a, miR455, and miR-543 (Figure 7A and Figure 8A), regulate c-Maf expression through its 3′-UTR. [score:4]

We conclude that miR-9, miR-137, miR-200c, miR-381, miR-455, miR-495, and miR-543 represent an FGF2 -dependent system of multiple miRNAs that target specific genes operating in pathways and processes related to the lens differentiation (via c-Maf, Med1/PBP, N-myc, and Nfat5), miRNA-regulated RNA processing (via Cpsf6 and Tnrc6b) and nuclear/chromatin -based processes (via Med1/PBP, As1l, and Kdm5b/Jarid1b/Plu1). [score:4]

We found that seven miRNAs, including miR-9, miR-137, miR-200c, miR-381, miR-455, miR-495, and miR-543, target at least two “early” genes examined (i. e., c-Maf, N-Myc, and Nfib). [score:3]

Three miRNAs from this cluster, including miR-495, miR-543, and miR-381, represent a group of most highly connected miRNAs in this system (Figure 6A) and regulate together multiple genes known to regulate lens fiber cell differentiation, including c-Maf (Figure 7 and Figure 10). [score:3]

This gross analysis is consistent with our findings of genes regulated by miR-495, miR-543, and miR-381 in lens that belong to these similar categories (Figure 5). [score:2]

We predict that several important regulatory genes of lens fiber cell differentiation, including c-Maf, Kdm5b/Jarid1b, Med1/PBP, Nfat5/OREBP, and N-Myc, are connected by multiple shared miRNAs, with four of them, including miR-381, miR-495, miR-382, and miR-543, encoded by a miRNA cluster on rat chromosome 6, a syntenic region with mouse chromosome 12, and human 14q32.2 imprinted regions. [score:2]

The miR-495 and miR-543 are neighbors, and miR-381 is located ~12.7 kb from miR-495. [score:1]

Seven miRNAs, including miR-9, miR-137, miR-200c, miR-381, miR-455, miR-495, and miR-543, and connections to specific functional groups of genes are shown. [score:1]

The miR-381, miR-495, miR-543, and miR-382 form a miRNA-gene cluster on rat chromosome 6q32. [score:1]

The most connected miRNA identified here through the 12 top-ranking transcripts, including miR-495, miR-200c, miR-543, miR-381, and miR-9 (Figure 6A), retained their high-connectivity positions as identified by independent analysis shown earlier in Figure 6A. [score:1]

Notably, miR-381, miR-495, and miR-543 form a miRNA-gene cluster on rat chromosome 6, and its syntenic regions on mouse and human chromosome 12 and 14, respectively (Sewer et al. 2005). [score:1]

[1 to 20 of 11 sentences]

[+] score: 12

Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-16-1, hsa-mir-17, hsa-mir-21, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-25, hsa-mir-26a-1, hsa-mir-26b, hsa-mir-30a, hsa-mir-31, hsa-mir-96, hsa-mir-99a, hsa-mir-16-2, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-182, hsa-mir-183, hsa-mir-211, hsa-mir-217, hsa-mir-218-1, hsa-mir-218-2, hsa-mir-221, hsa-mir-222, hsa-let-7g, hsa-let-7i, hsa-mir-15b, hsa-mir-23b, hsa-mir-30b, hsa-mir-125b-1, hsa-mir-132, hsa-mir-143, hsa-mir-145, hsa-mir-191, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-184, hsa-mir-190a, hsa-mir-195, rno-mir-322-1, rno-let-7d, rno-mir-335, rno-mir-342, rno-mir-135b, hsa-mir-30c-1, hsa-mir-299, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-379, hsa-mir-382, hsa-mir-342, hsa-mir-135b, hsa-mir-335, rno-let-7a-1, rno-let-7a-2, rno-let-7b, rno-let-7c-1, rno-let-7c-2, rno-let-7e, rno-let-7f-1, rno-let-7f-2, rno-let-7i, rno-mir-15b, rno-mir-16, rno-mir-17-1, rno-mir-21, rno-mir-23a, rno-mir-23b, rno-mir-24-1, rno-mir-24-2, rno-mir-25, rno-mir-26a, rno-mir-26b, rno-mir-30c-1, rno-mir-30e, rno-mir-30b, rno-mir-30d, rno-mir-30a, rno-mir-30c-2, rno-mir-31a, rno-mir-96, rno-mir-99a, rno-mir-125a, rno-mir-125b-1, rno-mir-125b-2, rno-mir-126a, rno-mir-132, rno-mir-143, rno-mir-145, rno-mir-183, rno-mir-184, rno-mir-190a-1, rno-mir-191a, rno-mir-195, rno-mir-211, rno-mir-217, rno-mir-218a-2, rno-mir-218a-1, rno-mir-221, rno-mir-222, rno-mir-299a, hsa-mir-384, hsa-mir-20b, hsa-mir-409, hsa-mir-412, hsa-mir-489, hsa-mir-494, rno-mir-489, rno-mir-412, rno-mir-542-1, rno-mir-379, rno-mir-494, rno-mir-382, rno-mir-409a, rno-mir-20b, hsa-mir-542, hsa-mir-770, hsa-mir-190b, hsa-mir-543, rno-mir-466c, rno-mir-17-2, rno-mir-182, rno-mir-190b, rno-mir-384, rno-mir-673, rno-mir-674, rno-mir-770, rno-mir-31b, rno-mir-191b, rno-mir-299b, rno-mir-218b, rno-mir-126b, rno-mir-409b, rno-let-7g, rno-mir-190a-2, rno-mir-322-2, rno-mir-542-2, rno-mir-542-3

Among the miRNAs examined, 79 miRNAs (24%) responded to the hyperandrogenic condition and interestingly, 80% of which were upregulated compared to the control group supporting the notion that hyperandrogenic condition down-regulates androgen receptors in the granulosa cells [35] which could be mediated by these upregulated miRNAs (rno-miR-379*, rno-let-7d, rno-miR-24, rno-miR-673, rno-miR-26b, rno-miR-335, rno-miR-382*, rno-miR-412, rno-miR-99a*, rno-miR-543, rno-miR-674-3p, rno-miR-409-3p). [score:9]

A list of differentially expressed miRNAs (Fold change ≥ 2 and their corresponding P value) is presented in Figure 4. Beside this group, miRNAs which were also highly abundant in DHT -treated ovaries are rno-miR-221, rno-miR-222, rno-miR-25, rno-miR-26b, rno-miR-379*, rno-let-7d, rno-miR-24, rno-miR-673, rno-miR-26b, rno-miR-335, rno-miR-382*, rno-miR-412, rno-miR-99a*, rno-miR-543, rno-miR-674-3p, rno-miR-409-3p. [score:3]

[1 to 20 of 2 sentences]

[+] score: 6

Other miRNAs from this paper: rno-mir-323, rno-mir-96, rno-mir-125a, rno-mir-127, rno-mir-141, rno-mir-145, rno-mir-146a, rno-mir-183, rno-mir-200c, rno-mir-200a, rno-mir-200b, rno-mir-429, rno-mir-409a, rno-mir-547, rno-mir-3585, rno-mir-155

All these miRNAs except miR-543-5p also displayed significant changes of expression (padj-value =< 5.2E-02) between groups C-C and HF-HF (Table 4). [score:3]

Remarkably all these miRNAs except miR-543-5p (shaded miRNA) also displayed significant changes of expression (padj-value = < 5.2E-02) between groups C-C and HF-HF, thus defining a subset of miRNAs repeatedly impacted by the perinatal unbalanced environment. [score:3]

[1 to 20 of 2 sentences]

[+] score: 3

Other miRNAs from this paper: rno-mir-216a, rno-mir-291a, rno-mir-760, rno-mir-490, rno-mir-291b

In the LHb we found reduced expression in LH animals of miR-543 relative to controls (Fig 4B). [score:3]

[1 to 20 of 1 sentences]

miRBase

4 publications mentioning rno-mir-543