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10 publications mentioning hsa-mir-605

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-605. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 13
Five of the twenty snoRNA-like miRNAs, mir-664, mir-151, mir-605, mir-215 and mir-140 were selected for this analysis because they are expressed in HeLa cells. [score:3]
Screenshots of the UCSC Genome Browser [48] displaying RefSeq genes (blue lines with hatch marks), miRNA hairpins (red blocks), snoRNAs (green blocks with hatch marks), repeat-elements (blue blocks with hatch marks) and TSDs (black blocks) are shown for the genomic regions surrounding mir-215 (A), mir-549 (B), mir-1266 (C) and mir-605 (D). [score:1]
Indeed, the H/ACA snoRNAs predicted in the extended region around mir-549, mir-140, mir-1262 and mir-605 are all predicted to serve as guides for experimentally validated pseudouridylation sites whose guides are unknown, making these interesting candidates for further studies. [score:1]
On the other hand, three reported miRNAs with snoRNA-like features, miR-549, miR-548m and miR-605, have been identified with fewer than 4 reads. [score:1]
C RT-PCR used to detect co-precipitated hsa-mir-664, hsa-mir-151, hsa-mir-605, has-mir-215 and has-mir-140 miRNA precursors, with E2 box H/ACA snoRNA as positive control and hsa-pri-let-7g miRNA, U3 box C/D snoRNA, U1 snRNA, 5S rRNA and GAPDH pre-mRNA as negative controls for dyskerin -associated RNAs. [score:1]
We tested the predictions by experimentally showing that the precursors of five of the predicted snoRNA-like miRNAs, mir-664, mir-151, mir-605, mir-215 and mir-140, interact with dyskerin, a protein component of functional H/ACA snoRNPs. [score:1]
Given that the extended region of mir-605 is predicted to serve as a guide for an experimentally validated pseudouridylation site whose guide is unknown, we postulate that this region encodes an H/ACA snoRNA rather than a miRNA. [score:1]
Shown in Figure 4D is the genomic region surrounding mir-605, which consists of two pairs of TSDs, one of which flanks a SINE repeat element and the other of which flanks the whole snoRNA/miRNA/SINE region. [score:1]
In particular, mir-605 has only been identified previously with one sequence read [45]. [score:1]
Mir-664 and mir-605 have not, to our knowledge, been further functionally validated and will require additional experimental evidence to confirm they are true miRNAs. [score:1]
1000507.g004 Figure 4Screenshots of the UCSC Genome Browser [48] displaying RefSeq genes (blue lines with hatch marks), miRNA hairpins (red blocks), snoRNAs (green blocks with hatch marks), repeat-elements (blue blocks with hatch marks) and TSDs (black blocks) are shown for the genomic regions surrounding mir-215 (A), mir-549 (B), mir-1266 (C) and mir-605 (D). [score:1]
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2
[+] score: 13
control or normal glucose Subsequently, the online database (TargetScan 6.2) predicted several miRNAs that could directly target NOD1, including miR-605, miR-924, miR-3194-3p, miR-495 and miR-4477a. [score:6]
control or normal glucoseSubsequently, the online database (TargetScan 6.2) predicted several miRNAs that could directly target NOD1, including miR-605, miR-924, miR-3194-3p, miR-495 and miR-4477a. [score:6]
b The levels of miR-605, miR-924, miR-3194-3p, miR-495 and miR-4477a were determined via quantitative RT-PCR. [score:1]
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3
[+] score: 12
In our study, miR-605 and miR-181d were predicted to be related to stroke for the first time and we validated the prediction, which were highly expressed in the blood of stroke patients. [score:3]
ESM1, KRAS, miR-181d, miR-181b-3p, miR-605-3p and miR-605-5p were highly expressed in the blood of stroke patients compare to healthy people. [score:3]
Six miRNAs (miRNA181-b, miRNA-181d, miRNA-605, has-let-7a, has-let-7b, and has-let-7f) were predicted to be related to stroke based on the targetgenes network (Fig. 5). [score:3]
Finally, ESM1, KRAS, miR-181d, miR-181b-3p, miR-605-3p and miR-605-5p were highly expressed in the blood of stroke patients compared to healthy people (Fig. 6). [score:2]
miR-181b, miR-181d and miR-605 are predicted based on the genes from miRanda database. [score:1]
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4
[+] score: 7
Two editing sites were associated with higher HDL cholesterol levels: chr9:95,085,457, which was located outside the mature miRNA (pri-mir-27b; P = 2.2e−05; FDR = 8.5%) and chr10:51,299,636 (mir-605-3p; P = 1.6e−06; FDR = 0.65%). [score:1]
RNA editing sites in mir-24-2, mir-605, mir-3126, and U88 had not previously been reported in REDIportal (Picardi et al., 2017) or DARNED (Kiran & Baranov, 2010). [score:1]
Six editing sites occurred in mature miRNAs: three in mir-605-3p and one each in mir-3138, mir-605-5p, and mir-24-2-3p. [score:1]
pri-mir-27b and mir-605 editing in aortic wall and internal mammary artery are associated with increased plasma levels of high-density lipoprotein. [score:1]
mir-27b has been linked to progression of atherosclerosis (Li et al., 2011a; Zhang et al., 2014b), and mir-605 is implicated in stroke (Yuan et al., 2016) and hypertension (Li et al., 2011b). [score:1]
We found an association between plasma HDL levels and editing of pri-mir-27b/mir-605. [score:1]
Stringent editing criteria (recurrence in > 50 samples) identified 18 editing sites in 10 miRNAs (mir-24-2, mir-27a, mir-27b, mir-605, mir-641, mir-1254, mir-1285-1, mir-1304, mir-3126, and mir-3138; Table S5) and 2 snoRNAs (U88 and SNORD17). [score:1]
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5
[+] score: 5
The level of miRNA expression change was also lower, since Log2 fold decreases ranged from −1.25 (hsa-miR-221) to −4.64 (hsa-miR-605) and Log2 fold increases ranged from 1.14 (hsa-miR-23b) to 2.87 (hsa-miR-125a-5p). [score:3]
06 hsa-miR-595 5.29 hsa-miR-92b −9.97 hsa-miR-601 5.88 hsa-miR-765 4.47 hsa-miR-98 5.05 hsa-miR-99a 6.41 TGF-β -treated hsa-miR-20b −1.29 hsa-let-7a 1.38 hsa-miR-221 −1.25 hsa-let-7d 1.43 hsa-miR-605 −4.64 hsa-let-7e 2 hsa-miR-638 −1.40 hsa-miR-125a-5p 2.87 hsa-miR-663 −2.06 hsa-miR-146a 2.72 hsa-miR-720 −2.40 hsa-miR-21 1.14 hsa-miR-23a 1.20 hsa-miR-23b 1.14 hsa-miR-30c 1.89 hsa-miR-483-5p 1.38 hsa-miR-574-5p 2.23 hsa-miR-99b 1.63 10.1371/journal. [score:1]
06 hsa-miR-595 5.29 hsa-miR-92b −9.97 hsa-miR-601 5.88 hsa-miR-765 4.47 hsa-miR-98 5.05 hsa-miR-99a 6.41 TGF-β -treated hsa-miR-20b −1.29 hsa-let-7a 1.38 hsa-miR-221 −1.25 hsa-let-7d 1.43 hsa-miR-605 −4.64 hsa-let-7e 2 hsa-miR-638 −1.40 hsa-miR-125a-5p 2.87 hsa-miR-663 −2.06 hsa-miR-146a 2.72 hsa-miR-720 −2.40 hsa-miR-21 1.14 hsa-miR-23a 1.20 hsa-miR-23b 1.14 hsa-miR-30c 1.89 hsa-miR-483-5p 1.38 hsa-miR-574-5p 2.23 hsa-miR-99b 1.63 10.1371/journal. [score:1]
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6
[+] score: 4
[36] Further studies indicated that p53 performs its function through regulating the expression of a range of miRNAs, such as miR-605, [37] miR-1246, [38] and miR-107. [score:4]
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7
[+] score: 4
010 Down-regulated  hsa-mir-605 −5.662. [score:4]
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8
[+] score: 3
The expression patterns of 10 of these (miR-146b, miR-193a, miR-193b, miR-218, miR-424, miR-450b-3p, miR-511, miR-573, miR-605 and miR-890) were similar at both time points. [score:3]
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9
[+] score: 1
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-17, hsa-mir-20a, hsa-mir-21, hsa-mir-25, hsa-mir-26a-1, hsa-mir-26b, hsa-mir-27a, hsa-mir-29a, hsa-mir-30a, hsa-mir-33a, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-99a, hsa-mir-101-1, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-106a, hsa-mir-16-2, hsa-mir-148a, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-10a, hsa-mir-34a, hsa-mir-181a-2, hsa-mir-181b-1, hsa-mir-181c, hsa-mir-182, hsa-mir-204, hsa-mir-205, hsa-mir-181a-1, hsa-mir-216a, hsa-mir-217, hsa-mir-223, hsa-mir-200b, hsa-let-7g, hsa-let-7i, hsa-mir-1-2, hsa-mir-15b, hsa-mir-23b, hsa-mir-27b, hsa-mir-30b, hsa-mir-122, hsa-mir-125b-1, hsa-mir-130a, hsa-mir-133a-1, hsa-mir-133a-2, hsa-mir-142, hsa-mir-191, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-146a, hsa-mir-149, hsa-mir-150, hsa-mir-200c, hsa-mir-1-1, hsa-mir-155, hsa-mir-181b-2, hsa-mir-106b, hsa-mir-29c, hsa-mir-200a, hsa-mir-101-2, hsa-mir-26a-2, hsa-mir-365a, hsa-mir-365b, hsa-mir-370, hsa-mir-375, hsa-mir-378a, hsa-mir-148b, hsa-mir-335, hsa-mir-133b, hsa-mir-451a, hsa-mir-146b, hsa-mir-494, hsa-mir-193b, hsa-mir-181d, hsa-mir-92b, hsa-mir-574, hsa-mir-33b, hsa-mir-378d-2, hsa-mir-216b, hsa-mir-103b-1, hsa-mir-103b-2, hsa-mir-378b, hsa-mir-378c, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-451b, hsa-mir-378j
Zhang M. W. Jin M. J. Yu Y. X. Zhang S. C. Liu B. Jiang X. Pan Y. F. Li Q. I. Ma S. Y. Chen K. Associations of lifestyle-related factors, hsa-miR-149 and hsa-miR-605 gene polymorphisms with gastrointestinal cancer risk Mol. [score:1]
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10
[+] score: 1
Other miRNAs from this paper: hsa-mir-196a-2
Id Said B Malkin D A functional variant in miR-605 modifies the age of onset in Li-Fraumeni syndromeCancer Genet. [score:1]
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