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5 publications mentioning hsa-mir-631

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-631. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 12
The marker SNP rs8028182 was found to be associated with sudden cardiac arrest in patients with coronary artery disease [63]; SULT1A1, an experimentally validated target of miR-631 [47], has been associated with the risk factor of coronary artery disease [64]. [score:7]
Additional precursor sequences of miRNAs containing in dels include miR-520h [39], [40], [41], miR-486 [42], miR-489 [43], miR-223 [44], miR-373 [45], miR-630 [46] and miR-1233 [17], which have been shown to be involved in cancer development, and miR-631, which is associated with risk of coronary artery disease [47]. [score:4]
Similarly, the in del rs5745925 in miR-631 is within the same LD block as the association study marker SNP rs8028182 in the CEU population. [score:1]
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[+] score: 10
We selected RNU6 and let-7 that have been wi dely used as references for the normalization of qRT-PCR data of target miRNAs and miR-631 according to the microarray data analysis. [score:3]
Hsa-miR-631, but not Let-7 and RNU6, showed non-significant differences between the groups (data not shown). [score:1]
The Ct value of miR-631 was used as an internal standard. [score:1]
To validate the RNA sequencing data, we performed a qRT-PCR analysis of hsa-let-7, hsa-miR-631, RNU6, hsa-miR-16-5p, hsa-miR-25-3p, hsa-miR-302d-3p, hsa-miR-378e, hsa-miR-570-3p, hsa-miR-574-5p, and hsa-miR-579. [score:1]
According to the literature let-7, RNU6 that have been wi dely used to normalize miRNAs in plasma and the miRNA data hsa-miR-631, were tested by qRT-PCR. [score:1]
Based on the literature and the microarray data, let-7, miRNA-631 and RNU6 were selected for testing in a random cohort of 24 plasma samples as possible “housekeeping” miRNA that could be used as an internal control. [score:1]
These findings suggested miR-631 was the best internal control to use for assessing changes in exosomal miRNA levels. [score:1]
We used hsa-miR-631 as the internal control because it had the most consistent level in plasma exosomes between the two groups mean value. [score:1]
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[+] score: 6
Other bone miRNAs, miR-631 and miR-574-5p 1, 9, were also tested in order to preclude a non-specific phenomenon related to a general upregulation of gene expression. [score:6]
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[+] score: 3
These analyses identified four miRNAs unique to pNK cells (has-miR-337, has-miR-422a, has-miR-549, and has-miR-618) and eight miRNAs uniquely expressed by PB NK cells (has-let-7b, has-miR-146b, has-miR-19b, has-miR-24, has-miR-347, has-miR-381, has-miR-517c, and has-miR-631). [score:3]
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[+] score: 3
83 *** hsa-mir-346 7.13 *** 69.13 *** hsa-mir-361-3p 4.51 *** 9.6 *** hsa-mir-483-3p 3.56 *** 68.61 *** hsa-mir-486-5p 2.85 *** 34.48 *** hsa-mir-574-3p 2.61 *** 43.22 *** hsa-mir-629* 16.62 *** 67.23 *** hsa-mir-885-5p 4.75 *** 43.73 *** Inhibited differentiation & high cell count hsa-mir-193b 38.04 *** 102.74 * Hits of functional screen Relative percentage of myotubes 1, % of control p value, Mann Whitney test Relative cell count 2, % of control p value, Mann Whitney test hsa-mir-369-3p 61.75 *** 103.6 * hsa-mir-381 61.75 *** 105.31 * hsa-mir-886-5p 38.04 *** 112.86 *** hsa-mir-940 21.37 *** 112.35 *** Enhanced differentiation hsa-mir-98 104.51 * 87.82 *** High cell count hsa-mir-631 92.63 ** 103.43 *** 1see Material and Methods; 2 *: p<0.05; **: p<0.01; *** p<0.005; − = not significant. [score:3]
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