sort by

8 publications mentioning hsa-mir-653

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-653. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 13
For instance, TUBG1 is inhibited by mir-152, STMN1 is inhibited by mir-210, LRRFIP2 and UNG are inhibited by mir-214, GCN1L1 is inhibited by mir-221, RPL37 is inhibited by mir-381, and PIGN is inhibited by mir-320a and mir-653. [score:13]
[1 to 20 of 1 sentences]
2
[+] score: 9
Liu et al. [29] found that expression of 4 miRNAs was significantly upregulated (miR-136, miR-703, miR-30b, and miR-107), while miR-653 and miR-598 were significantly downregulated. [score:9]
[1 to 20 of 1 sentences]
3
[+] score: 8
SNP ID small RNA ID Type Chr P-value eQTL P-value GWAS GWAS phenotype rs8033963 hsa-miR-184 mature-miRNA 15 1.98E-06 1.01E-02 BMI rs6658641 hsa-miR-197-3p mature-miRNA 1 1.57E-04 4.93E-02 BMI rs2440129 hsa-miR-195-3p mature-miRNA 17 2.44E-05 3.58E-02 BMI rs2053005 SNORD18A snoRNA 15 6.83E-09 4.57E-02 BMI rs16868443 hsa-miR-653 mature-miRNA 7 1.38E-04 3.70E-02 WHR(adjBMI) rs6658641 hsa-miR-197-3p mature-miRNA 1 1.57E-04 7.89E-04 LDL rs2986039 hsa-miR-1307-3p mature-miRNA 10 6.31E-06 1.84E-02 HDL rs6658641 hsa-miR-197-3p mature-miRNA 1 1.57E-04 1.14E-03 TCWhile on the whole, none of the cis-SNPs were genome-wide significant in the GWAS data, they were significantly enriched for nominally significant (p<0.05) SNPs in the BMI GWAS results ([65], binomial p = 0.007), indicating either their pleiotropic effect, or metabolic trait regulation through small RNA expression levels. [score:4]
SNP ID small RNA ID Type Chr P-value eQTL P-value GWAS GWAS phenotype rs8033963 hsa-miR-184 mature-miRNA 15 1.98E-06 1.01E-02 BMI rs6658641 hsa-miR-197-3p mature-miRNA 1 1.57E-04 4.93E-02 BMI rs2440129 hsa-miR-195-3p mature-miRNA 17 2.44E-05 3.58E-02 BMI rs2053005 SNORD18A snoRNA 15 6.83E-09 4.57E-02 BMI rs16868443 hsa-miR-653 mature-miRNA 7 1.38E-04 3.70E-02 WHR(adjBMI) rs6658641 hsa-miR-197-3p mature-miRNA 1 1.57E-04 7.89E-04 LDL rs2986039 hsa-miR-1307-3p mature-miRNA 10 6.31E-06 1.84E-02 HDL rs6658641 hsa-miR-197-3p mature-miRNA 1 1.57E-04 1.14E-03 TC While on the whole, none of the cis-SNPs were genome-wide significant in the GWAS data, they were significantly enriched for nominally significant (p<0.05) SNPs in the BMI GWAS results ([65], binomial p = 0.007), indicating either their pleiotropic effect, or metabolic trait regulation through small RNA expression levels. [score:4]
[1 to 20 of 2 sentences]
4
[+] score: 3
Finally, the authors identified three microRNAs (miR-134, miR-543, and miR-653) as Braf-rs1 and Braf -targeting and, by mutagenizing their MREs on Braf mRNA, proved that they are the mediators of the protective effects exerted by the pseudogene on the parental gene. [score:3]
[1 to 20 of 1 sentences]
5
[+] score: 1
Florian et al. discovered that BRAFP1 functions as a ceRNA of BRAF in humans and mice, competing for miR-134, miR-543, miR-653, miR-30a, miR-182 and miR-876[9]. [score:1]
[1 to 20 of 1 sentences]
6
[+] score: 1
48E-051.589 rs12178 ZBTB34 0.456 hsa-miR-1267, hsa-miR-501-5p, hsa-miR-3613-3p, hsa-miR-653 A/C/G/T rs12178 1 9.66E-05 1.277 Eleven putative miRNA-related SNPs link to SCZ-GWAS SNPs with a significance of p < 0.0001. [score:1]
[1 to 20 of 1 sentences]
7
[+] score: 1
severe (p<0.05) cfa-let-7a, cfa-let-7b, cfa-let-7c, cfa-let-7f, cfa-miR-127, cfa-miR-1271, cfa-miR-130a, cfa-miR-139, cfa-miR-17, cfa-miR-1836, cfa-miR-1837, cfa-miR-20a, cfa-miR-23a, cfa-miR-25, cfa-miR-26a, cfa-miR-29b, cfa-miR-378, cfa-miR-421, cfa-miR-502, cfa-miR-503, cfa-miR-542, cfa- miR-652, cfa-miR-653, cfa-miR-872 Normal and mild vs. [score:1]
[1 to 20 of 1 sentences]
8
[+] score: 1
Other miRNAs from this paper: hsa-mir-32, hsa-mir-489, bta-mir-32, bta-mir-653, bta-mir-489
In the second region, all three genes were identified: CALCR, MIR653, and MIR489. [score:1]
[1 to 20 of 1 sentences]