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10 publications mentioning dre-mir-34b

Open access articles that are associated with the species Danio rerio and mention the gene name mir-34b. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 32
Other miRNAs from this paper: dre-mir-7b, dre-mir-7a-1, dre-mir-7a-2, dre-mir-34a, dre-mir-181b-1, dre-mir-181b-2, dre-mir-182, dre-mir-183, dre-mir-181a-1, dre-mir-219-1, dre-mir-219-2, dre-mir-221, dre-mir-222a, dre-mir-430a-1, dre-mir-430b-1, dre-mir-430c-1, dre-let-7a-1, dre-let-7a-2, dre-let-7a-3, dre-let-7a-4, dre-let-7a-5, dre-let-7a-6, dre-let-7b, dre-let-7c-1, dre-let-7c-2, dre-let-7d-1, dre-let-7d-2, dre-let-7e, dre-let-7f, dre-let-7g-1, dre-let-7g-2, dre-let-7h, dre-let-7i, dre-mir-7a-3, dre-mir-9-1, dre-mir-9-2, dre-mir-9-4, dre-mir-9-3, dre-mir-9-5, dre-mir-9-6, dre-mir-9-7, dre-mir-92b, dre-mir-96, dre-mir-100-1, dre-mir-100-2, dre-mir-124-1, dre-mir-124-2, dre-mir-124-3, dre-mir-124-4, dre-mir-124-5, dre-mir-124-6, dre-mir-125b-1, dre-mir-125b-2, dre-mir-125b-3, dre-mir-128-1, dre-mir-128-2, dre-mir-132-1, dre-mir-132-2, dre-mir-135c-1, dre-mir-135c-2, dre-mir-137-1, dre-mir-137-2, dre-mir-138-1, dre-mir-153a, dre-mir-181c, dre-mir-200a, dre-mir-218a-1, dre-mir-218a-2, dre-mir-219-3, dre-mir-375-1, dre-mir-375-2, dre-mir-454a, dre-mir-430c-2, dre-mir-430c-3, dre-mir-430c-4, dre-mir-430c-5, dre-mir-430c-6, dre-mir-430c-7, dre-mir-430c-8, dre-mir-430c-9, dre-mir-430c-10, dre-mir-430c-11, dre-mir-430c-12, dre-mir-430c-13, dre-mir-430c-14, dre-mir-430c-15, dre-mir-430c-16, dre-mir-430c-17, dre-mir-430c-18, dre-mir-430a-2, dre-mir-430a-3, dre-mir-430a-4, dre-mir-430a-5, dre-mir-430a-6, dre-mir-430a-7, dre-mir-430a-8, dre-mir-430a-9, dre-mir-430a-10, dre-mir-430a-11, dre-mir-430a-12, dre-mir-430a-13, dre-mir-430a-14, dre-mir-430a-15, dre-mir-430a-16, dre-mir-430a-17, dre-mir-430a-18, dre-mir-430i-1, dre-mir-430i-2, dre-mir-430i-3, dre-mir-430b-2, dre-mir-430b-3, dre-mir-430b-4, dre-mir-430b-6, dre-mir-430b-7, dre-mir-430b-8, dre-mir-430b-9, dre-mir-430b-10, dre-mir-430b-11, dre-mir-430b-12, dre-mir-430b-13, dre-mir-430b-14, dre-mir-430b-15, dre-mir-430b-16, dre-mir-430b-17, dre-mir-430b-18, dre-mir-430b-5, dre-mir-430b-19, dre-mir-430b-20, dre-let-7j, dre-mir-181a-2, dre-mir-34c, dre-mir-222b, dre-mir-138-2, dre-mir-181a-4, dre-mir-181a-3, dre-mir-181a-5, dre-mir-181b-3, dre-mir-181d, dre-mir-128-3
miR-100 also shows robust habenular expression (Figure K in5) while miR-92b and miR-34b are expressed in ventricular cells adjacent to the mature habenular nuclei (Figure J in, and Figure L in5). [score:5]
For instance, miR-34 shows conserved expression in the larval and adult hindbrain (Mauthner neuron, (MAC) and presumptive octavolateral area (OA) in Figure 5c; MAC and octavolateral nuclei (medial octavolateral (MON), anterior octaval (AON), magnocellular octaval (MaON) in Figure 5d) but also expands to include forebrain and midbrain cells of the habenulae (Had in Figure 5f), posterior tuberculum (nucleus of paraventricular organ (nPVO) in Figure 5e), pretectum (magnocellular superficial (PSm), accessory (APN) in Figures M and N in), optic tectum as well as novel areas of the dorsal hindbrain (cerebellar granular layer, facial and vagal lobes;, and Tables D and I in7). [score:3]
Additional data file 5 is a figure showing miR-34 expression in the zebrafish brain. [score:3]
miR-34 expression in the zebrafish brain. [score:3]
In contrast, miR-34 expression is absent from forebrain and midbrain and present only in the caudal ventral and lateral isthmus and hindbrain, including ventral and lateral medulla oblongata cells (MO in Figure 5c), presumptive octaval area (OA in Figure 5c), reticular formation cells (intermediate reticular formation-(IMRF) and Mauthner cell (MAC) in Figure 5c;, and Table D in7). [score:3]
Several other miRNAs show robust expression in restricted populations of adult ventricular or periventricular cells, including miR-34b (Figures I and L in5). [score:3]
Similar to miR-34, miR-218a expression expands rostrally in the adult brain. [score:3]
Click here for file miR-34 expression in the zebrafish brain. [score:3]
In addition to miR-34 (Figure 5f), several other miRNAs show spatially restricted expression within the habenulae of adults. [score:3]
miR-222 and miR-34 are expressed in neural cells in restricted subdivisions along the rostro-caudal axis of the larval brain. [score:3]
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[+] score: 24
The miR-34 family was usually recognized as the tumor suppressors that control cell proliferation and cell-cycle progression through silencing oncogenic targets [43]. [score:5]
Earlier studies have proved that the miR-34 family acts as regulators of gene expression in cell cycle progression [32], senescence [33], and apoptosis [34]. [score:4]
Zhao L. L. Jin F. Ye X. Zhu L. Yang J. S. Yang W. J. Expression profiles of miRNAs and involvement of miR-100 and miR-34 in regulation of cell cycle arrest in ArtemiaBiochem. [score:4]
In this study, we started with miR-34a to explore the functional roles of the miR-34 family in spermatogenesis using miR-34a homozygous knockout zebrafish produced by the CRISPR/Cas9 system, and tried to identify the targeted gene of miR-34a using the bioinformatics and luciferase reporter assay. [score:3]
Wu J. W. Bao J. Q. Kim M. Yuan S. Q. Tang C. Zheng H. L. Mastick G. S. Xu C. Yan W. Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesisProc. [score:2]
Hermeking H. The miR-34 family in cancer and apoptosisCell Death Differ. [score:1]
In vertebrates, the miR-34 family is an evolutionary conserved family, including three members: miR-34a, miR-34b, and miR-34c. [score:1]
At present, however, the precise role of the miR-34 family during spermatogenesis is still poorly understood in vivo. [score:1]
Recent studies revealed the miR-34 family might have roles in spermatogenesis and sperm motility [35, 36]. [score:1]
The miR-34 family is highly evolutionarily conserved in vertebrates and contains three closely related members: miR-34a/b/c [31]. [score:1]
Other evidences suggest that the miR-34 family also has a crucial role in spermatogenesis and sperm motility [35, 36]. [score:1]
[1 to 20 of 11 sentences]
[+] score: 15
As previously reported, some of the specifically expressed miRNAs in RPL5 MO (such as Dre-mir-142a-3p, Dre-miR-34b and Dre-miR-15a*) and some miRNAs with two-fold higher expression (such as Dre-miR-150, Dre-miR-223 and Dre-miR-155) are involved in the development and function of the hematological system and most of the above-listed miRNAs participate in normal hematologic functions by regulating the expression of c-myb [28– 31]. [score:9]
Moreover, dre-miR-34b, dre-miR-15a* and dre-miR-150, which were thought to target c-myb, were significantly up-regulated. [score:6]
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[+] score: 12
Our results showed only one miRNA (dre-mir-34-3p) with target genes overrepresented in the down-regulated gene set. [score:6]
We speculate that it is not probable that dre-mir-34-3p plays an important role in the changed gene expression patterns observed under cold stress. [score:3]
The miRNA dre-mir-34-3p was expressed at very low levels (29 in the cold library and 20 in the control library) in the brain and was not significantly different between the two conditions. [score:3]
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[+] score: 9
MiR-34 family members (miR-34a, -34b, and -34c) are upregulated in the heart in response to stress and the silencing of the entire miR-34 family could protect the heart against pathological cardiac remo deling and improve cardiac functions (Bernardo et al., 2012). [score:4]
Therapeutic inhibition of the mir-34 family attenuates pathological cardiac remo deling and improves heart function. [score:3]
These recent studies show an emerging role of miR-34a (and the miR-34 family) as potential regulator of heart remo deling. [score:2]
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[+] score: 3
Other miRNAs from this paper: hsa-mir-34a, hsa-mir-34b, hsa-mir-34c, dre-mir-34a, dre-mir-34c
As mentioned previously, CARF was reported to regulate p53 pathway [15, 16], and p53 pathway could regulate canonical Wnt signaling through transactivating microRNA-34 [21]. [score:3]
[1 to 20 of 1 sentences]
[+] score: 2
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-17, hsa-mir-21, hsa-mir-29a, hsa-mir-96, mmu-let-7g, mmu-let-7i, mmu-mir-124-3, mmu-mir-140, mmu-mir-181a-2, mmu-mir-182, mmu-mir-183, mmu-mir-194-1, mmu-mir-200b, hsa-mir-34a, hsa-mir-181a-2, hsa-mir-181b-1, hsa-mir-181c, hsa-mir-182, hsa-mir-183, hsa-mir-181a-1, hsa-mir-200b, mmu-mir-34c, mmu-mir-34b, mmu-let-7d, hsa-let-7g, hsa-let-7i, hsa-mir-124-1, hsa-mir-124-2, hsa-mir-124-3, hsa-mir-140, hsa-mir-194-1, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, mmu-mir-15a, mmu-mir-21a, mmu-mir-29a, mmu-mir-96, mmu-mir-34a, mmu-mir-135b, hsa-mir-200c, hsa-mir-181b-2, mmu-mir-17, mmu-mir-200c, mmu-mir-181a-1, mmu-mir-124-1, mmu-mir-124-2, mmu-mir-181b-1, mmu-mir-181c, hsa-mir-194-2, mmu-mir-194-2, hsa-mir-34b, hsa-mir-34c, hsa-mir-376c, hsa-mir-376a-1, mmu-mir-376a, hsa-mir-135b, mmu-mir-181b-2, mmu-mir-376b, dre-mir-34a, dre-mir-181b-1, dre-mir-181b-2, dre-mir-182, dre-mir-183, dre-mir-181a-1, dre-let-7a-1, dre-let-7a-2, dre-let-7a-3, dre-let-7a-4, dre-let-7a-5, dre-let-7a-6, dre-let-7b, dre-let-7c-1, dre-let-7c-2, dre-let-7d-1, dre-let-7d-2, dre-let-7e, dre-let-7f, dre-let-7g-1, dre-let-7g-2, dre-let-7h, dre-let-7i, dre-mir-15a-1, dre-mir-15a-2, dre-mir-17a-1, dre-mir-17a-2, dre-mir-21-1, dre-mir-21-2, dre-mir-29a, dre-mir-96, dre-mir-124-1, dre-mir-124-2, dre-mir-124-3, dre-mir-124-4, dre-mir-124-5, dre-mir-124-6, dre-mir-140, dre-mir-181c, dre-mir-194a, dre-mir-194b, dre-mir-200b, dre-mir-200c, hsa-mir-376b, hsa-mir-181d, hsa-mir-507, dre-let-7j, dre-mir-135b, dre-mir-181a-2, hsa-mir-376a-2, mmu-mir-376c, dre-mir-34c, mmu-mir-181d, mmu-mir-21b, mmu-let-7j, mmu-mir-21c, mmu-let-7k, dre-mir-181a-4, dre-mir-181a-3, dre-mir-181a-5, dre-mir-181b-3, dre-mir-181d, mmu-mir-124b
This data suggested that apoptosis in the inner ear, followed by hearing damage in this mo del previously linked to programmed cell death, is partly mediated by members of the miR-34 family. [score:1]
Due to their previously known role in apoptosis, levels of the miR-34 family were examined in RNA extracted from cochleae of treated mice by qRT-PCR analysis. [score:1]
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[+] score: 1
Other miRNAs from this paper: hsa-mir-34b
Toyota M Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancerCancer Res. [score:1]
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[+] score: 1
Likewise, miR-1, miR-124, miR-125b, miR-132, bantam, miR-34 and the miR-310 cluster have all been implicated in the modulation of synaptic homeostasis [70]– [76]. [score:1]
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[+] score: 1
In zebrafish, miR-34 was the only reported maternal miRNA, which was involved in embryonic neurogenesis [32]. [score:1]
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