sort by

14 publications mentioning mmu-mir-490

Open access articles that are associated with the species Mus musculus and mention the gene name mir-490. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 123
Other miRNAs from this paper: mmu-mir-145a, mmu-mir-145b
We predicted miR-490-3p might be the potential miRNA for targeting Nanog mRNA, and our results showed an increase of miR-490-3p and a corresponding decrease of Nanog expression after PFOS exposure, To further validate the hypothesis that miR-490-3p regulates Nanog expression after PFOS exposure, we transfected miR-490-3p mimics and a negative control precursor, miR-490-3p inhibitor and a inhibitor control precursor in 293T cells. [score:12]
sWe predicted miR-490-3p might be the potential miRNA for targeting Nanog mRNA, and our results showed an increase of miR-490-3p and a corresponding decrease of Nanog expression after PFOS exposure, To further validate the hypothesis that miR-490-3p regulates Nanog expression after PFOS exposure, we transfected miR-490-3p mimics and a negative control precursor, miR-490-3p inhibitor and a inhibitor control precursor in 293T cells. [score:12]
The results showed that the relative expression levels of miR-490-3p were increased with miR-490-3p mimics and that of miR-490-3p expression levels were decreased with miR-490-3p inhibitor in 293T cells (Figure 3C). [score:7]
Human 293T cells were cultured to about 50% confluence and transfection was carried out using Lipofectamine 2000 (Invitrogen Corp, CA, USA) with 50 nM miR-490-3p mimics, a negative control,100 nM miR-490-3p inhibitor or a inhibitor control in 6-well plates respectively. [score:5]
Over -expression of miR-490-3p reduced Nanog expression. [score:5]
To explore the mechanisms by which PFOS disturbed the observed altered expression of Sox2, Nanog in mESCs, the expressions of miR-145 and miR-490-3p which may target Sox2, Nanog were evaluated. [score:5]
0074968.g003 Figure 3Over -expression of miR-490-3p reduced Nanog expression. [score:5]
These findings allow us to conclude that miR-490-3p and its host gene Chrm2 regulate Nanog expression in mESCs, providing novel insights into the molecular mechanisms of developmental toxicity of PFOS. [score:5]
Meanwhile, results here also suggested that PFOS could affect the expression of Chrm2, which might, at least in part, modulate miR-490-3p expression. [score:5]
Effects of PFOS on the Potential and the Relative Expression of miR-145 and miR-490-3p in mESCsWe detected the effects of PFOS on the potential by examining the expression of self-renewal factors (Oct4, Sox2, Nanog). [score:5]
Synthetic miRNA precursor molecules of miR-490-3p, a negative control, miR-490-3p inhibitor and a inhibitor control (GenePharma, Shanghai, China) were used in transfection experiments. [score:5]
To confirm the efficiency of transfection assay, the miRNA expression level of miR-490-3p was measured after transfection with miR-490-3p mimics and a negative control precursor, miR-490-3p inhibitor and a inhibitor control precursor. [score:4]
These results suggested that miR-490-3p could directly target Nanog. [score:4]
In addition, our findings showed that miR-490-3p could directly target Nanog. [score:4]
Effects of PFOS on pluripotency and expressions of miR-145, miR-490-3p in mESCs. [score:3]
org), we predicted that miR-490-3p might be the potential miRNA for targeting Nanog mRNA. [score:3]
The 3′UTR sequence of Nanog predicted to interact with miR-490-3p or a mutated sequence with the predicted target sites were inserted into the KpnI and SacI sites of pGL3 promoter vector (Genscript, Nanjing, China). [score:3]
By combing the results obtained from transfection and dual luciferase reporter assay, we firstly confirmed that miR-490-3p regulated the expression of Nanog in mESCs, which provided a new insight into PFOS -induced toxicity in mESCs. [score:3]
0074968.g002 Figure 2Effects of PFOS on pluripotency and expressions of miR-145, miR-490-3p in mESCs. [score:3]
org and identified miR-490-3p as targeting Nanog. [score:3]
A significantly positive correlation was found between the expression levels of miR-490-3p and Chrm2 (R [2] = 0.7902, p<0.001. [score:3]
Effects of PFOS on the Potential and the Relative Expression of miR-145 and miR-490-3p in mESCs. [score:3]
The expression of miRNAs (has/ mmu-miR-145, has/ mmu-miR-490-3p, U6) were analyzed using SYBR PCR Master Mix reagent kits (Takara) according to the manufacturer’s instructions. [score:3]
The mRNA and protein levels of Nanog were evaluated after transfection for 24 h. As expected, qRT-PCR analysis showed that the relative expression levels of Nanog mRNA was decreased with miR-490-3p mimics and Nanog mRNA was increased with miR-490-3p inhibitor in 293T cells (Figure 3B). [score:3]
We compared the expression levels of miR-490-3p host gene Chrm2 after PFOS exposure by qRT-PCR (Figure 3A). [score:2]
Reporter activity was significantly decreased after miR-490-3p overexpression compared to control (P<0.05). [score:2]
We found that both miR-145 and miR-490-3p were dose dependently increased after PFOS exposure. [score:1]
Figure S2 Correlation between the levels of miR-490-3p and Chrm2 by Pearson correlation analysis. [score:1]
Cholinergic muscarinic receptor 2 (Chrm2), as the host gene of miR-490-3p, was identified by miRBase [40]. [score:1]
Figure S2), indicating that miR-490-3p was transcribed together with its host gene Chrm2. [score:1]
Cells were cultured with various concentrations of PFOS (0.2 µM, 2 µM, 20 µM, and 200 µM) or DMSO as control for 24 h. (B) Cells were transfected with 50 nM miR-490 mimics or 100 nM miR-490 inhibitor for 24 h. qRT-PCR was performed to evaluate the mRNA level of Nanog. [score:1]
In order to explore a potential relationship between miR-490-3p and Chrm2, the Pearson correlation analysis was performed. [score:1]
[1 to 20 of 32 sentences]
2
[+] score: 41
As shown in Figure 3, the expressions of miR-711, miR-714, miR-744, miR -2137, miR -5130, miR -346, and miR -328 was still upregulated in the I/R group, but the expression of miR-24 and miR-490 were downregulated, compared to the control group grafts. [score:10]
The expressions of miR-711, miR-714, miR-744, miR-2137, miR-5130, miR-1892, miR-328, miR-346, miR-5099, and miR-705 were significantly upregulated in I/R injured heart grafts, while miR-490, miR-491, miR-210, miR-362, miR-24, miR-423, miR-128, miR-328, miR -181, and miR-532 were downregulated. [score:9]
The findings of our study demonstrate that miR-711, miR-2137 miR-705, miR-5130, miR-346, miR-714, and miR-744 were significantly upregulated (>2 fold change) in I/R injured hearts, while miR-210, miR-490, miR-491, miR-425, miR-423-3p, and miR-532-3p were downregulated. [score:7]
For example, miR-2137, miR-5130 and miR-5112 were highly expressed in heart tissues; miR-490, miR-491, miR-181, miR-362, miR-425, and miR-3104 were expressed at quite a low level (Ct value ∼ over 30), whereas 32 out of those 58 altered miRNA were expressed at an extremely low level in hearts and there were almost no Ct value detected by qPCR. [score:7]
As expected, miR-2137, miR-210, miR-5130, and miR-328 were highly expressed in cardiomyocytes, while miR-490, miR-491, and miR-211 were expressed at a low level. [score:5]
There was no significant difference in the expression of miR-490 between the two groups (Figure 4B). [score:3]
[1 to 20 of 6 sentences]
3
[+] score: 29
In Fig.   3a, NOR (10, 30 μM) significantly downregulated mRNA expression of miR-31, but not miR-219 and miR-490 in CD4 [+] T cells under hypoxic atmosphere. [score:6]
MiRs are small noncoding RNA molecules and intrinsic miR-31 expression in CD11b [+] DCs is increased under hypoxic microenvironment [4]; DIM and I3C decrease miR-31, miR-219, and miR-490 expressions in draining lymph nodes of mice with delayed-type hypersensitivity [7]. [score:5]
Furthermore, 3, 3'-diindolylmethane (DIM) and indole-3-carbinol (I3C), the classical AhR agonists, promote Treg differentiation by targeting miR-31, miR-219, and miR-490 4, 5, 7. Thus, quantitative-PCR (Q-PCR) assay was performed to assess effect of NOR on mRNA expressions of miR-31, miR-219, and miR-490 in CD4 [+] T cells. [score:4]
Furthermore, 3, 3'-diindolylmethane (DIM) and indole-3-carbinol (I3C), the classical AhR agonists, promote Treg differentiation by targeting miR-31, miR-219, and miR-490 4, 5, 7. Thus, quantitative-PCR (Q-PCR) assay was performed to assess effect of NOR on mRNA expressions of miR-31, miR-219, and miR-490 in CD4 [+] T cells. [score:4]
In addition, miR-31, miR-219, and miR-490 can bind with 3′-untranslated region of Foxp3 gene to regulate Treg differentiation [7]. [score:4]
Fig. 3 a CD4 [+] T cells were cultured with anti-CD3/CD28 (2 µg/ml), NOR (1, 3, 10, 30 μM), and TCDD (5 nM) in hypoxia for 24 h. The mRNA expressions of miR-31, miR-219, and miR-490 were analyzed by Q-PCR. [score:3]
Normal group a CD4 [+] T cells were cultured with anti-CD3/CD28 (2 µg/ml), NOR (1, 3, 10, 30 μM), and TCDD (5 nM) in hypoxia for 24 h. The mRNA expressions of miR-31, miR-219, and miR-490 were analyzed by Q-PCR. [score:3]
[1 to 20 of 7 sentences]
4
[+] score: 15
Other miRNAs from this paper: mmu-mir-30a, mmu-mir-101a, mmu-mir-125a, mmu-mir-125b-2, mmu-mir-132, mmu-mir-134, mmu-mir-135a-1, mmu-mir-138-2, mmu-mir-142a, mmu-mir-150, mmu-mir-154, mmu-mir-182, mmu-mir-183, mmu-mir-24-1, mmu-mir-194-1, mmu-mir-200b, mmu-mir-122, mmu-mir-296, mmu-mir-21a, mmu-mir-27a, mmu-mir-92a-2, mmu-mir-96, rno-mir-322-1, mmu-mir-322, rno-mir-330, mmu-mir-330, rno-mir-339, mmu-mir-339, rno-mir-342, mmu-mir-342, rno-mir-135b, mmu-mir-135b, mmu-mir-19a, mmu-mir-100, mmu-mir-139, mmu-mir-212, mmu-mir-181a-1, mmu-mir-214, mmu-mir-224, mmu-mir-135a-2, mmu-mir-92a-1, mmu-mir-138-1, mmu-mir-181b-1, mmu-mir-125b-1, mmu-mir-194-2, mmu-mir-377, mmu-mir-383, mmu-mir-181b-2, rno-mir-19a, rno-mir-21, rno-mir-24-1, rno-mir-27a, rno-mir-30a, rno-mir-92a-1, rno-mir-92a-2, rno-mir-96, rno-mir-100, rno-mir-101a, rno-mir-122, rno-mir-125a, rno-mir-125b-1, rno-mir-125b-2, rno-mir-132, rno-mir-134, rno-mir-135a, rno-mir-138-2, rno-mir-138-1, rno-mir-139, rno-mir-142, rno-mir-150, rno-mir-154, rno-mir-181b-1, rno-mir-181b-2, rno-mir-183, rno-mir-194-1, rno-mir-194-2, rno-mir-200b, rno-mir-212, rno-mir-181a-1, rno-mir-214, rno-mir-296, mmu-mir-376b, mmu-mir-370, mmu-mir-433, rno-mir-433, mmu-mir-466a, rno-mir-383, rno-mir-224, mmu-mir-483, rno-mir-483, rno-mir-370, rno-mir-377, mmu-mir-542, rno-mir-542-1, mmu-mir-494, mmu-mir-20b, mmu-mir-503, rno-mir-494, rno-mir-376b, rno-mir-20b, rno-mir-503-1, mmu-mir-1224, mmu-mir-551b, mmu-mir-672, mmu-mir-455, mmu-mir-466b-1, mmu-mir-466b-2, mmu-mir-466b-3, mmu-mir-466c-1, mmu-mir-466e, mmu-mir-466f-1, mmu-mir-466f-2, mmu-mir-466f-3, mmu-mir-466g, mmu-mir-466h, mmu-mir-504, mmu-mir-466d, mmu-mir-872, mmu-mir-877, rno-mir-466b-1, rno-mir-466b-2, rno-mir-466c, rno-mir-872, rno-mir-877, rno-mir-182, rno-mir-455, rno-mir-672, mmu-mir-466l, mmu-mir-466i, mmu-mir-466f-4, mmu-mir-466k, mmu-mir-466j, rno-mir-551b, rno-mir-490, rno-mir-1224, rno-mir-504, mmu-mir-466m, mmu-mir-466o, mmu-mir-466c-2, mmu-mir-466b-4, mmu-mir-466b-5, mmu-mir-466b-6, mmu-mir-466b-7, mmu-mir-466p, mmu-mir-466n, mmu-mir-466b-8, rno-mir-466d, mmu-mir-466q, mmu-mir-21b, mmu-mir-21c, mmu-mir-142b, mmu-mir-466c-3, rno-mir-322-2, rno-mir-503-2, rno-mir-466b-3, rno-mir-466b-4, rno-mir-542-2, rno-mir-542-3
DEX treatment up-regulated the expression of miRNA-483, miRNA-181a-1, miRNA-490 and miRNA-181b-1, while it down-regulated the levels of miR-122, miR-466b, miR-200b, miR-877, miR-296, miRNA-27a and precursor of miR-504. [score:9]
The expression of miRNA-483, miRNA-181a-1, miRNA-490 and miRNA and miRNA-181b-1 was up-regulated in response to dexamethasone treatment. [score:6]
[1 to 20 of 2 sentences]
5
[+] score: 14
Here, we intended to identify suitable MREs for bladder cancer specific adenovirus -mediated TRAIL expression from the miRNAs with downregulated expression in bladder cancer, including miR-1 [18- 21], miR-99a [22], miR-100 [23], miR-101 [24, 25], miR-125b [23, 26, 27], miR-133a [18, 20, 21, 23, 28- 30], miR-143 [22, 23, 31- 33], miR-145 [21, 23, 29- 31, 34], miR-195-5p [35], miR-199a-3p [36], miR-200 [37, 38], miR-203 [39, 40], miR-205 [37], miR-218 [21, 41], miR-490-5p [42], miR-493 [43], miR-517a [44], miR-574-3p [45], miR-1826 [46] and let-7c [42]. [score:8]
The involved MREs sequences in our study were described in detail in Table  1. Table 1 MiRNA response elements (MREs) for bladder cancer-specific downregulated miRNAs miRNA primer sequences miR-1Forward: 5′-TCGAGACAAACACC ACATTCCAACAAACACC ACATTCCAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TGGAATGTGGTGTTTGT TGGAATGTGGTGTTTGTC-3′ miR-99aForward: 5′-TCGAGACAAACACC TACGGGTACAAACACC TACGGGTACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT ACCCGTAGGTGTTTGT ACCCGTAGGTGTTTGTC-3′ miR-101Forward: 5′-TCGAGACAAACACC GTACTGTACAAACACC GTACTGTACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT ACAGTACGGTGTTTGT ACAGTACGGTGTTTGTC-3′ miR-133Forward: 5′-TCGAGACAAACACC GGACCAAAACAAACACC GGACCAAAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TTTGGTCCGGTGTTTGT TTTGGTCCGGTGTTTGTC-3′ miR-218Forward: 5′-TCGAGACAAACACC AAGCACAAACAAACACC AAGCACAAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TTGTGCTTGGTGTTTGT TTGTGCTTGGTGTTTGTC-3′ miR-490-5pForward: 5′-TCGAGACAAACACC ATCCATGACAAACACC ATCCATGACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT CATGGATGGTGTTTGT CATGGATGGTGTTTGTC-3′ miR-493Forward: 5′-TCGAGACAAACACC ACCTTCAACAAACACC ACCTTCAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TGAAGGTGGTGTTTGT TGAAGGTGGTGTTTGTC-3′ miR-517aForward: 5′-TCGAGACAAACACC TGCACGAACAAACACC TGCACGAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TCGTGCAGGTGTTTGT TCGTGCAGGTGTTTGTC-3′The underscored sequences indicated MREs of miR-1, miR-99a, miR-101, miR-133 and miR-218, miR-490-5p, miR-493 and miR-517a. [score:3]
The involved MREs sequences in our study were described in detail in Table  1. Table 1 MiRNA response elements (MREs) for bladder cancer-specific downregulated miRNAs miRNA primer sequences miR-1Forward: 5′-TCGAGACAAACACC ACATTCCAACAAACACC ACATTCCAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TGGAATGTGGTGTTTGT TGGAATGTGGTGTTTGTC-3′ miR-99aForward: 5′-TCGAGACAAACACC TACGGGTACAAACACC TACGGGTACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT ACCCGTAGGTGTTTGT ACCCGTAGGTGTTTGTC-3′ miR-101Forward: 5′-TCGAGACAAACACC GTACTGTACAAACACC GTACTGTACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT ACAGTACGGTGTTTGT ACAGTACGGTGTTTGTC-3′ miR-133Forward: 5′-TCGAGACAAACACC GGACCAAAACAAACACC GGACCAAAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TTTGGTCCGGTGTTTGT TTTGGTCCGGTGTTTGTC-3′ miR-218Forward: 5′-TCGAGACAAACACC AAGCACAAACAAACACC AAGCACAAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TTGTGCTTGGTGTTTGT TTGTGCTTGGTGTTTGTC-3′ miR-490-5pForward: 5′-TCGAGACAAACACC ATCCATGACAAACACC ATCCATGACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT CATGGATGGTGTTTGT CATGGATGGTGTTTGTC-3′ miR-493Forward: 5′-TCGAGACAAACACC ACCTTCAACAAACACC ACCTTCAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TGAAGGTGGTGTTTGT TGAAGGTGGTGTTTGTC-3′ miR-517aForward: 5′-TCGAGACAAACACC TGCACGAACAAACACC TGCACGAACAAACACCGC-3′Reverse: 5′-GGCCGCGGTGTTTGT TCGTGCAGGTGTTTGT TCGTGCAGGTGTTTGTC-3′The underscored sequences indicated MREs of miR-1, miR-99a, miR-101, miR-133 and miR-218, miR-490-5p, miR-493 and miR-517a. [score:3]
[1 to 20 of 3 sentences]
6
[+] score: 11
Other miRNAs from this paper: mmu-mir-1249, mmu-mir-466j, mmu-mir-7684
miR-7684-5p and miR-466j were upregulated, while miR-1249-5p and miR-490-3p were downregulated (Figure 7B). [score:7]
Prior studies showed that miR-490-3p regulates cell proliferation and apoptosis by targeting CCND1, CDK1, and HMGA2 [23– 25]. [score:4]
[1 to 20 of 2 sentences]
7
[+] score: 8
These upregulated miRNAs include certain known miRNAs (mmu-miR-148b-5p, mmu-miR-879-5p, mmu-miR-144-3p, mmu-miR-540-5p, mmu-miR-582-5p, mmu-miR-15b-5p, mmu-miR-210-5p, mmu-miR-871-3p, mmu-miR-3103-5p, mmu-miR-16-1-3p, mmu-miR-470-5p, mmu-miR-190b-5p, mmu-miR-384-5p and mmu-miR-490-5p), as well as some novel miRNAs (novel_mir_46, novel_mir_214 and novel_mir_213) with their stem loop structures by Miredp (S3 Fig). [score:4]
Through sequencing miRNAs for their quantifications, we show that some known miRNAs (miR-148b-5p, miR-879-5p, miR-144-3p, miR-540-5p, miR-582-5p, miR-15b-5p, miR-210-5p, miR-871-3p, miR-3103-5p, miR-16-1-3p, miR-470-5p, miR-190b-5p, miR-384-5p and miR-490-5p) are upregulated in CUMS -induced depression mice (Table 3), which degrade mRNAs listed in Table 1. In other words, the analysis from miRNA sequencing is consistent to the analysis from mRNA sequencing. [score:4]
[1 to 20 of 2 sentences]
8
[+] score: 7
Of these, eight (miR-193b, miR-199a-3p/hsa-miR-199b-3p, miR-455-3p, miR-210, miR-381 (also known as miR-381-3p), miR-92a, miR-320c, and miR-136) were upregulated, while the other four (miR-490-5p, miR-4287, miR-BART8*, and miR-US25-1*) were downregulated during this process [22]. [score:7]
[1 to 20 of 1 sentences]
9
[+] score: 4
In addition, metformin modulated the expression of a number of miRNAs (let-7f, miR-30b, miR-362, miR-376c, miR-466h, miR-490, and miR-574) involved in the regulation of the cell cycle, which is a crucial mechanism in the AMPK -mediated activity of this drug 42. [score:4]
[1 to 20 of 1 sentences]
10
[+] score: 3
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-19a, hsa-mir-20a, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-25, hsa-mir-26a-1, hsa-mir-30a, hsa-mir-33a, hsa-mir-96, hsa-mir-98, hsa-mir-103a-2, hsa-mir-103a-1, mmu-let-7g, mmu-let-7i, mmu-mir-23b, mmu-mir-30a, mmu-mir-30b, mmu-mir-99b, mmu-mir-125a, mmu-mir-125b-2, mmu-mir-9-2, mmu-mir-133a-1, mmu-mir-146a, mmu-mir-155, mmu-mir-182, mmu-mir-183, mmu-mir-24-1, mmu-mir-191, mmu-mir-199a-1, hsa-mir-199a-1, mmu-mir-200b, hsa-mir-30c-2, hsa-mir-30d, mmu-mir-30e, hsa-mir-181b-1, hsa-mir-182, hsa-mir-183, hsa-mir-199a-2, hsa-mir-199b, hsa-mir-221, hsa-mir-223, hsa-mir-200b, mmu-mir-299a, mmu-let-7d, hsa-let-7g, hsa-let-7i, hsa-mir-23b, hsa-mir-30b, hsa-mir-125b-1, hsa-mir-133a-1, hsa-mir-133a-2, hsa-mir-191, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-146a, mmu-mir-30c-1, mmu-mir-30c-2, mmu-mir-30d, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, mmu-mir-20a, mmu-mir-21a, mmu-mir-23a, mmu-mir-24-2, mmu-mir-26a-1, mmu-mir-96, mmu-mir-98, mmu-mir-103-1, mmu-mir-103-2, mmu-mir-148b, mmu-mir-351, hsa-mir-200c, hsa-mir-155, hsa-mir-181b-2, mmu-mir-19a, mmu-mir-25, mmu-mir-200c, mmu-mir-223, mmu-mir-26a-2, mmu-mir-221, mmu-mir-199a-2, mmu-mir-199b, mmu-mir-9-1, mmu-mir-9-3, mmu-mir-181b-1, mmu-mir-125b-1, hsa-mir-30c-1, hsa-mir-299, hsa-mir-99b, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-361, mmu-mir-361, hsa-mir-365a, mmu-mir-365-1, hsa-mir-365b, hsa-mir-375, mmu-mir-375, hsa-mir-148b, mmu-mir-133a-2, mmu-mir-133b, hsa-mir-133b, mmu-mir-181b-2, mmu-mir-433, hsa-mir-429, mmu-mir-429, mmu-mir-365-2, hsa-mir-433, hsa-mir-490, hsa-mir-193b, hsa-mir-92b, mmu-mir-193b, mmu-mir-92b, hsa-mir-103b-1, hsa-mir-103b-2, mmu-mir-299b, mmu-mir-133c, mmu-let-7j, mmu-mir-30f, mmu-let-7k, mmu-mir-9b-2, mmu-mir-9b-1, mmu-mir-9b-3
The 3′ UTR of mouse Xbp1 mRNA contains several putative target sites for miR-199, miR-299, miR-433, miR-221, and miR-490. [score:3]
[1 to 20 of 1 sentences]
11
[+] score: 3
Notwithstanding, the “mut” allele generates binding sites for six alternative miRNAs (Table  1) of which four, miR-143 (3p and 5p), miR-490-3p, miR-1246, and miR-1261, were expressed in the human 1.1E7 pancreatic cell line (Fig.   5a). [score:3]
[1 to 20 of 1 sentences]
12
[+] score: 1
Only one of the 5 patients (#3) showed a 2.7-fold increase in miR-21, a 5.4-fold increase in miR-363 and a 5-fold increase in miR-490 (Fig 8). [score:1]
[1 to 20 of 1 sentences]
13
[+] score: 1
Zhang W. Zhang C. Chen H. Li L. Tu Y. Liu C. Shi S. Zen K. Liu Z. Evaluation of microRNAs miR-196a, miR-30a-5P, and miR-490 as biomarkers of disease activity among patients with FSGS Clin. [score:1]
[1 to 20 of 1 sentences]
14
[+] score: 1
Eleven miRNAs were randomly selected for qPCR analysis for each age: GD 17.0 miR-1843-5p, miR-485-3p, miR-711, miR-3962, miR-3067-3p, miR-212-3p, miR-669i, miR-877, miR-26b-3p, miR-465c-3p, let-7b-3p; GD 18.0 miR-1843-5p, miR-485-3p, miR-3473d, miR-132-5p, miR-3074-1-3p, miR-128-2-5p, miR-130b-5p, miR-490-5p, miR-669h-3p, miR-3058-5p, miR-146b. [score:1]
[1 to 20 of 1 sentences]