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12 publications mentioning bta-mir-106a

Open access articles that are associated with the species Bos taurus and mention the gene name mir-106a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 53
Other miRNAs from this paper: bta-mir-99a
In this study, we aimed to assess the effects of IFNT on miR-106a expression and to predict the location of genomic binding sites for interferon responsive factors (IRFs) that can regulate the expression of genes involved in endometrial response to embryo implantation. [score:6]
IFNT induced expression of PR and miR-106a and downregulation of ESR1 and PR. [score:6]
On the other hand, when IFNT combined with PDBU were applied, miR-106a expression was not affected, pointing towards a counter-regulation of PDBU over IFNT. [score:4]
This can explain the upregulation of miR-106a when BEND cells are treated with IFNT and imply a potential role of this miRNA in embryo maternal communication in cattle. [score:4]
Bioinformatic analyses detected that PLA2G4A was associated to IRF-1 and IRF-6, while ESR1, PR and PTGS2 were associated to only IRF-6. All genes exhibit one motif per IRF, except miR-106a that had three binding sites for IRF-6. We report the IFNT regulatory effect on miR-106a expression through IRF-6 in bovine endometrial cells. [score:4]
Expression of miR-106a is regulated by IFNT. [score:4]
Fig. 2 Normalized fold change expression of miR-106a for BEND cells. [score:3]
This effect was most likely due to the activity of IFNT, which increased the expression of miR-106a approximately 30 % when applied alone. [score:3]
We have previously characterized the expression of miRNAs in bovine endometrium across the estrous cycle and detected the expression of miR-106a [20]. [score:3]
An overall significant effect was detected on the expression of miR-106a (Fig.   2). [score:3]
IFNT might induce binding of IRF-6 to the promoter region of miR-106a inducing its expression. [score:3]
The aim of this study was to unravel the molecular mechanisms involved in IFNT signalling and its regulation of miR-106a. [score:2]
Interestingly, miR-106a was 3x enriched for IRF-6 in its promoter region (Table  4). [score:1]
Therefore, it is possible that miR-106a contributes to the control of endometrial responses to IFNT and oxytocin. [score:1]
In this study, we investigated the expression miR-106a and genes for prostaglandin-endoperoxide synthase 2 (PTGS2), phospholipase A2, group IVA (PLA2G4A), estrogen receptor 1 (ESR1) and progesterone receptor (PR) in response to IFNT in BEND cells and searched for interferon responsive factors (IRFs) binding sites in their promoter genomic regions. [score:1]
We have previously described microRNAs (miRNAs) profiles in bovine endometrium, detecting miR-106a, relevant for embryo maternal communication. [score:1]
For each experiment, six biological replicates were usedEvidence showed that miR-106a responds to IFNT alone and in combination with P4. [score:1]
The miR-106a is known to have roles embryo-endometrial cross talk [15– 19]. [score:1]
We decided to search for promoter binding sites at genes relevant for BEND function and miR-106a, leaving out thousands of genomic regions where IRFs can bind. [score:1]
For each experiment, six biological replicates were used Evidence showed that miR-106a responds to IFNT alone and in combination with P4. [score:1]
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[+] score: 9
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-17, hsa-mir-18a, hsa-mir-19a, hsa-mir-19b-1, hsa-mir-19b-2, hsa-mir-20a, hsa-mir-22, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-25, hsa-mir-27a, hsa-mir-29a, hsa-mir-30a, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-98, hsa-mir-99a, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-106a, hsa-mir-148a, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-10a, hsa-mir-10b, hsa-mir-181a-2, hsa-mir-181b-1, hsa-mir-181c, hsa-mir-182, hsa-mir-181a-1, hsa-mir-221, hsa-let-7g, hsa-let-7i, hsa-mir-1-2, hsa-mir-15b, hsa-mir-27b, hsa-mir-30b, hsa-mir-130a, hsa-mir-152, hsa-mir-191, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-185, hsa-mir-193a, hsa-mir-320a, hsa-mir-200c, hsa-mir-1-1, hsa-mir-181b-2, hsa-mir-29c, hsa-mir-30c-1, hsa-mir-99b, hsa-mir-130b, hsa-mir-30e, hsa-mir-363, hsa-mir-374a, hsa-mir-375, hsa-mir-378a, hsa-mir-148b, hsa-mir-331, hsa-mir-339, hsa-mir-423, hsa-mir-20b, hsa-mir-491, hsa-mir-193b, hsa-mir-181d, hsa-mir-92b, hsa-mir-320b-1, hsa-mir-320c-1, hsa-mir-320b-2, hsa-mir-378d-2, bta-mir-29a, bta-let-7f-2, bta-mir-148a, bta-mir-18a, bta-mir-20a, bta-mir-221, bta-mir-27a, bta-mir-30d, bta-mir-320a-2, bta-mir-99a, bta-mir-181a-2, bta-mir-27b, bta-mir-30b, bta-mir-10a, bta-mir-15b, bta-mir-181b-2, bta-mir-193a, bta-mir-20b, bta-mir-30e, bta-mir-92a-2, bta-mir-98, bta-let-7d, bta-mir-148b, bta-mir-17, bta-mir-181c, bta-mir-191, bta-mir-200c, bta-mir-22, bta-mir-29b-2, bta-mir-29c, bta-mir-423, bta-let-7g, bta-mir-10b, bta-mir-24-2, bta-mir-30a, bta-let-7a-1, bta-let-7f-1, bta-mir-30c, bta-let-7i, bta-mir-25, bta-mir-363, bta-let-7a-2, bta-let-7a-3, bta-let-7b, bta-let-7c, bta-let-7e, bta-mir-15a, bta-mir-19a, bta-mir-19b, bta-mir-331, bta-mir-374a, bta-mir-99b, hsa-mir-374b, hsa-mir-320d-1, hsa-mir-320c-2, hsa-mir-320d-2, bta-mir-1-2, bta-mir-1-1, bta-mir-130a, bta-mir-130b, bta-mir-152, bta-mir-181d, bta-mir-182, bta-mir-185, bta-mir-24-1, bta-mir-193b, bta-mir-29d, bta-mir-30f, bta-mir-339a, bta-mir-374b, bta-mir-375, bta-mir-378-1, bta-mir-491, bta-mir-92a-1, bta-mir-92b, bta-mir-9-1, bta-mir-9-2, bta-mir-29e, bta-mir-29b-1, bta-mir-181a-1, bta-mir-181b-1, bta-mir-320b, bta-mir-339b, bta-mir-19b-2, bta-mir-320a-1, bta-mir-193a-2, bta-mir-378-2, hsa-mir-378b, hsa-mir-320e, hsa-mir-378c, bta-mir-148c, hsa-mir-374c, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-378j, bta-mir-378b, bta-mir-378c, bta-mir-378d, bta-mir-374c, bta-mir-148d
MiR-92a, miR-19b and miR-363 were found to be highly expressed, while miR-17-5p, miR-18a, miR-20b and miR-106a were lowly expressed. [score:5]
As mentioned above, miR-17-5p, miR-363, miR-106a, miR-18a, miR-19b, miR-92a, miR-20b and miR-92b formed a complex cluster and family network, and they also showed different expression patterns. [score:3]
In the genome, miR-92a/19b showed three copies; miR-363 and miR-20b had two copies; while miR-17, miR-18a and miR-106a had one copy. [score:1]
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[+] score: 9
MiR-20 and miR-106a were identified to promote the renewal of mouse spermatogonial stem cells (SSCs) at the post-transcriptional level via targeting STAT3 and Ccnd1 [19], and miR-221/222 were found to play a crucial role in maintaining the undifferentiated state of spermatogonia through repression of KIT expression [20]. [score:5]
He Z MiRNA-20 and mirna-106a regulate spermatogonial stem cell renewal at the post-transcriptional level via targeting STAT3 and Ccnd1Stem Cells. [score:4]
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[+] score: 6
The c-Myc-regulated microRNA-17~92 (miR-17~92) and miR-106a~363 clusters target hCYP19A1 and hGCM1 to inhibit human trophoblast differentiation. [score:6]
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[+] score: 3
The function of miR-17, especially miR-17-5p, when in combination with miR-20a and miR-106a is to inhibit monocyte proliferation, differentiation and maturation, as appeared in a review by Lindsay [39]. [score:3]
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[+] score: 3
The results indicated that bta-miR-106a, bta-miR-20b and bta-miR-135a may play roles as regulators of mammary gland development and mammary epithelial cell proliferation. [score:3]
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[+] score: 3
Six miRNAs (miR-16b, miR-19a, miR-106, miR142–5 p, miR-196a and miR-2454) had the expression in agreement between qRT-PCR and microarray, however the other six (miR92a, miR-92b, miR-101, miR-103, miR-296 and miR-2368*) had divergent results. [score:3]
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[+] score: 3
Other miRNAs from this paper: bta-mir-19b
For example, Kumar et al. [43] showed that miR-19b and miR-106a target CYP19A1 transcripts. [score:3]
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[+] score: 1
In contrast, the plasma samples were enriched with moderate concentrations of miRNAs associated with adipose tissue, such as miR-15a, miR-19a/b, miR-21, miR-27b, miR-92a/b, miR-103, miR-106a/b, miR-107, miR-125b, and miR-150 [11, 12]. [score:1]
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[+] score: 1
The hub miRNAs in the green module from the high IMF group (e. g. bta-miR-106a, bta-miR-671) (Fig. 6) and midnightblue module from the low IMF group (e. g. bta-miR-122, bta-miR-1291) (Fig. 7) identified in the, were also found correlated with the DH genes in the PCIT analysis (Additional file 7: Tables S5 and S6). [score:1]
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[+] score: 1
While searching the genomic location for all miRNAs, we found six new genomic locations for annotated miRNAs like bta-mir-106, 24, 26, 199a and let-7b (Additional file 1). [score:1]
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[+] score: 1
However, in livestock, few studies have been described so far, with the exception of studies using porcine tissues where miR-93, miR-25, miR-106a, miR-17-5p, and miR-26a have been reported as stable reference miRNAs [12– 13]. [score:1]
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