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1 publications mentioning cel-mir-784

Open access articles that are associated with the species Caenorhabditis elegans and mention the gene name mir-784. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 22
control Description (WormBase)Normally upregulated by hsf-1 upon heat shock miR-784 1.35 miR-784 is expressed in head neurons and the vulva, however the precise function of miR-784 is unknown. [score:6]
The log [2] fold change of miR-784, a miRNA normally upregulated by HSF-1 upon HS, in the hsf-1(+); +HS vs control condition. [score:4]
Induction of miR-784, miR-231, miR-86, miR-53, miR-47, and miR-34 by HSF-1 during HS is predicted to have the largest impact on the suppression of genes encoding proteins involved in the regulation of transcription and behavior, as these processes have enrichment scores of 5.49 and 4.93, respectively (S7A Fig). [score:4]
Through this method of data analysis, we found that miR-784, miR-231, miR-86, miR-53, miR-47, and miR-34 are normally upregulated by HSF-1 during HS. [score:4]
To validate our miRNA-seq data, we performed qRT-PCR with independent samples for miR-784 and miR-239b, two miRNA genes identified to have altered HSF-1 -dependent expression, and found that similar results were obtained (Fig 1D and 1E). [score:3]
While the functions of miR-784, miR-231, miR-86, miR-53, and miR-47 are currently unknown, miR-34 encodes a microRNA that is highly conserved with orthologues in Drosophila, mouse, and human [30]. [score:1]
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