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13 publications mentioning rno-mir-455

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-455. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 47
Other miRNAs from this paper: hsa-mir-34a, hsa-mir-122, rno-mir-34a, rno-mir-122, hsa-mir-455
However, the expression of miR-455-3p was significantly downregulated across the entire course of TAA treatments (except 28-d with high dose). [score:6]
While the expression of rno-miR-455-3p was decreased with an increase in the dose as well as followed a downregulation with almost all the time points (excluding high dose at 28-d). [score:6]
At the bottom of this figure, the higher expression values of rno-miR-455-3p in the control compared to treated samples, as a result, this miRNA is identified as significantly downregulated with all three doses and all four time points. [score:5]
Notably, rno-miR-34a-5p and rno-miR-455-3p were detected differentially expressed following all time-points and doses compared to the control group (Fig.   6), indicating the significant relevance of the expression of both miRNAs to the treatments. [score:4]
In a previous study, miR-455-3p has been observed as significantly downregulated in poorly differentiated HCC. [score:4]
On the other hand, rno-miR-455-3p, a downregulated DEM, was observed in 11 out of 12 treatment conditions (excluding high dose at 28-d). [score:4]
Expression of miR-34a-5p, miR-455-3p and miR-122. [score:3]
Importantly, the expression levels of two DEMs (i. e., rno-miR-34a-5p and rno-miR-455-3p) were found to be changed with almost all treatment conditions. [score:3]
Our pathway enrichment analysis of miR-455-3p targets also found several relevant biological signaling pathways including pathways in cancer, focal adhesion, pancreatic cancer, glioma, basal cell carcinoma, and Mapk-, Wnt- and mTOR-signaling, suggesting alteration of liver architecture. [score:3]
In case of miR-455-3p, the nuclear alteration and cellular loci classifiers cover the maximum AUC values (Figure  S1). [score:1]
In addition to miR-34a-5p, we found miR-455-3p which can potentially be used as an early and sensitive biomarker for the detection of liver injury and pre HCC. [score:1]
On the other hand, the nuclear alteration and cellular loci classifiers out of 6 histopathological features were found to obtain the maximum AUC values for miR-455-3p (Figure  S1). [score:1]
To further evaluate the correlation between these two DEMs and cancer progression, we carried out a regression analysis between the histopathological features and the expression patterns of miR-34a-5p, and miR-455-3p during TAA exposures. [score:1]
Information on two potential early and sensitive miRNA biomarkers (miR-34a-5p and miR-455-3p) and their associated signaling is given on the top two rows. [score:1]
Notably, miR-455-3p and miR-34a-5p were involved most of the cancer-related functional pathways. [score:1]
On the other hand, rno-miR-455-3p was comparatively higher in the controls than treated samples. [score:1]
Two potential biomarkers (miR-34a-5p and miR-455-3p) out of 48 overlapping DEMs are found common across all the treatments. [score:1]
The miR-34a-5p and miR-455-3p were selected to investigate their expression changes during TAA treatments. [score:1]
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2
[+] score: 38
Another study used lentiviruses to silence β-catenin in gastric cancer cell lines and found the dysregulated expression of a number of miRNAs including increased expression of miR-210 and decreased expression of miR-455-3p [60]. [score:8]
The microarray results demonstrated significantly decreased expression of 54 miRNAs in the renal cortices from the Cd -treated group versus the saline control group, and miR-193b-3p, miR-455-3p, and miR-342-3p demonstrated a more abundant expression level and a two-fold or greater decreased expression in the Cd-treatment group versus the saline control group. [score:7]
The microarray results presented here also demonstrated decreased expression of let-7e-3p, and both the microarray and real-time PCR validation from our study demonstrated decreased expression of miR-455-3p. [score:5]
miR-193b-3p, miR-455-3p, and miR-342-3p demonstrated more abundant expression and a two-fold or greater significant decreased expression with Cd treatment. [score:5]
Fabbri et al. treated HepG2 human hepatoma cells with 10 µM Cd for 24 h and reported decreased expression of 12 miRNAs, including members of the let-7 family (let-7a, let-7b, let-7e, and let-7g) and miR-455-3p [58]. [score:3]
As shown here, the decreased expression of miR-455-3p in the renal cortices from Cd-treatment animals was confirmed by real-time PCR. [score:3]
By contrast, real-time PCR validation demonstrated a significant 52% decrease in miR-455-3p expression in the Cd-treatment group (Figure 3G). [score:3]
Selected miRNAs that demonstrated a statistically significant (p ≤ 0.05) altered expression using µParaflo™ microRNA microarray were validated using the following TaqMan [®] Advanced miRNA assays: miR-21-5p (rno481342_mir), miR-34a-5p (rno481304_mir), miR-146b-5p (rno480941_mir), miR-224-5p (rno481010_mir), miR-3084a-3p (rno481040_mir), miR-3084c-3p (rno481313_mir), and miR-455-3p (rno481396_mir). [score:2]
Both miR-210-5p and miR-455-3p were also dysregulated in our study, and we have previously shown that Cd alters β-catenin sub-cellular localization and activity in NRK-52E rat proximal tubule epithelial cells and causes a loss of β-catenin at cell–cell contacts [6, 53, 54, 55, 56, 57]. [score:2]
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3
[+] score: 24
B13 cells that were transduced with Ad-PNM showed upregulation of 6 miRNAs (miR-134-5p, miR-455-3p, miR-384-5p, miR-137-3p, miR-135a-5p and miR-22-5p) and downregulation of 2 miRNAs (miR-335-3p and miR-148a-5p). [score:7]
The up-regulation of miR-455-3p, miR-137-3p and miR-135a-5p due to PNM expression observed in our panels (Table 3) was also validated in this single PCR study (Fig 6H–6J). [score:6]
To the best of our knowledge, there are no reports describing a link between β cell development or function and the remaining overexpressed miRNAs that were identified in the present study: miR-455-3p, miR-384-5p, miR-137-3p and miR-135a-5p. [score:4]
Relative miRNA expression levels of miR-200c-3p (A), miR-141-3p (B), miR-325-3p (C), miR-2137 (D), miR-210-3p (E), miR-181a-5p (F), miR-204-5p (G), miR-455-3p (H), miR-137-3p (I), miR-135a-5p (J), miR-384-5p (K) in rat exocrine fractions, rat islets, AR42J cells, B13 cells and B13 transduced with Ad-GFP or Ad-PNM at 4 days post-transduction, quantified by individual qPCR assays. [score:2]
Of note, using single qPCR assays we demonstrated that miR-455-3p, miR-137-3p and miR-135a-5p were expressed at very similar levels in reprogrammed B13 cells and pancreatic islets, suggesting a mechanistic relationship between these miRNAs and insulin production and/or β cell phenotype. [score:2]
0145116.g006 Fig 6Relative miRNA expression levels of miR-200c-3p (A), miR-141-3p (B), miR-325-3p (C), miR-2137 (D), miR-210-3p (E), miR-181a-5p (F), miR-204-5p (G), miR-455-3p (H), miR-137-3p (I), miR-135a-5p (J), miR-384-5p (K) in rat exocrine fractions, rat islets, AR42J cells, B13 cells and B13 transduced with Ad-GFP or Ad-PNM at 4 days post-transduction, quantified by individual qPCR assays. [score:2]
9 miRNAs were present in two categories; 5 of them were common between Tables 1 and 2 (miR-181a-5p, miR-204-5p and miR-2137, miR-421-3p and miR-483-3p), two miRNAs were present in both Tables 2 and 3 (miR-148a-5p and piR-335-3p) and the remaining two miRNAs were classified both in Tables 1 and 3 (miR-137-3p and miR-455-3p). [score:1]
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4
[+] score: 19
We conclude that miR-9, miR-137, miR-200c, miR-381, miR-455, miR-495, and miR-543 represent an FGF2 -dependent system of multiple miRNAs that target specific genes operating in pathways and processes related to the lens differentiation (via c-Maf, Med1/PBP, N-myc, and Nfat5), miRNA-regulated RNA processing (via Cpsf6 and Tnrc6b) and nuclear/chromatin -based processes (via Med1/PBP, As1l, and Kdm5b/Jarid1b/Plu1). [score:4]
The current data suggest that multiple miRNAs, including miR-9, miR-137, miR-155, miR-301a, miR455, and miR-543 (Figure 7A and Figure 8A), regulate c-Maf expression through its 3′-UTR. [score:4]
To determine whether the aforementioned miRNAs identified in rat lens explant system are also expressed during mammalian lens development in vivo, we conducted ISH analysis of miR-9, miR-143, miR-155, miR-301a, miR-381, and miR-455 in E14.5 and newborn (P0) lenses. [score:4]
We found that seven miRNAs, including miR-9, miR-137, miR-200c, miR-381, miR-455, miR-495, and miR-543, target at least two “early” genes examined (i. e., c-Maf, N-Myc, and Nfib). [score:3]
At this stage both miR-381 (H) and miR-455 (J) expression domains are restricted to the equatorial zone of the lens in proliferating, migrating, and differentiating lens cells. [score:3]
Seven miRNAs, including miR-9, miR-137, miR-200c, miR-381, miR-455, miR-495, and miR-543, and connections to specific functional groups of genes are shown. [score:1]
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5
[+] score: 9
Several microRNAs involved in inflammation have also been shown to undergo changes in expression following astrocyte activation in vitro [101], including the upregulation of miR-146 and the downregulation of miR-455, which is in agreement with our results. [score:9]
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6
[+] score: 7
D. Effect of miR-204, miR-93, miR-17, miR-302d, miR-455, miR-212 or miR-30a overexpression on Nurr1 3’ UTR long. [score:3]
Seven miRNAs were selected: miR-17, miR-204, miR-455, miR-30a, miR-212, miR-302d and miR-93. [score:1]
The intersection of these 3 databases gave 14 miRNAs in common and we choose miR-204, miR-30a, miR-302d, miR-212, miR-93, miR-17 and miR-455 for further experimentation. [score:1]
The seed sites of miRNAs selected for the specific part of the long 3’UTR are: miR-204 in nucleotide 870, miR-212 in nucleotide 1014, miR-93 and miR-302d in nucleotide 1063, miR-17 in nucleotide 1070, miR-455 in nucleotide 1177 and miR-30a in nucleotide 1279. [score:1]
The precursor sequences of the miR-145, miR-302d, miR-130a, miR-204, miR-93, miR-17, miR-455, miR-212 and miR-30a were cloned on pEGP-CE vector, acquired from Cell Biolabs Inc (7758 Arjons Drive San Diego, CA 92126 USA). [score:1]
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7
[+] score: 5
Yao S. Tang B. Li G. Fan R. Cao F. miR-455 inhibits neuronal cell death by targeting TRAF3 in cerebral ischemic strokeNeuropsychiatr. [score:5]
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8
[+] score: 3
Out of the 14 miRNAs that were detected to be differentially expressed using NGS (Table  4), five (rno-let-7d-5p, rno-miR-100-5p, rno-miR-203a-3p, rno-miR-21-5p, rno-miR-320-3p) were represented on the TLDA-A, while nine (rno-miR-378a-3p, mmu-miR-5100, rno-miR-30e-3p, rno-miR-125b-2-3p, rno-miR-320-5p, rno-miR-3473, rno-miR-21-3p, rno-miR-455-5p, and hsa-miR-7641) were not. [score:3]
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9
[+] score: 3
That is, miR-140, miR-31, miR-875-5p and miR-141 were expressed mainly during tooth morphogenesis identified at embryonic day 16 (E16), whereas miR-689, miR-720, miR-711 and miR-455 were prevalent at the cytodifferentiation stage (E18) [8]. [score:3]
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10
[+] score: 3
We found that our transcript sequence could be a target of three miRNAs: hsa-miR-455-5p, has-miR-640 and has-miR-1909-3p. [score:3]
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11
[+] score: 2
Cardiosome mediated regulation of MMP9 in diabetic heart: role of mir29b and mir455 in exercise. [score:2]
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12
[+] score: 2
Other miRNAs from this paper: mmu-mir-30a, mmu-mir-101a, mmu-mir-125a, mmu-mir-125b-2, mmu-mir-132, mmu-mir-134, mmu-mir-135a-1, mmu-mir-138-2, mmu-mir-142a, mmu-mir-150, mmu-mir-154, mmu-mir-182, mmu-mir-183, mmu-mir-24-1, mmu-mir-194-1, mmu-mir-200b, mmu-mir-122, mmu-mir-296, mmu-mir-21a, mmu-mir-27a, mmu-mir-92a-2, mmu-mir-96, rno-mir-322-1, mmu-mir-322, rno-mir-330, mmu-mir-330, rno-mir-339, mmu-mir-339, rno-mir-342, mmu-mir-342, rno-mir-135b, mmu-mir-135b, mmu-mir-19a, mmu-mir-100, mmu-mir-139, mmu-mir-212, mmu-mir-181a-1, mmu-mir-214, mmu-mir-224, mmu-mir-135a-2, mmu-mir-92a-1, mmu-mir-138-1, mmu-mir-181b-1, mmu-mir-125b-1, mmu-mir-194-2, mmu-mir-377, mmu-mir-383, mmu-mir-181b-2, rno-mir-19a, rno-mir-21, rno-mir-24-1, rno-mir-27a, rno-mir-30a, rno-mir-92a-1, rno-mir-92a-2, rno-mir-96, rno-mir-100, rno-mir-101a, rno-mir-122, rno-mir-125a, rno-mir-125b-1, rno-mir-125b-2, rno-mir-132, rno-mir-134, rno-mir-135a, rno-mir-138-2, rno-mir-138-1, rno-mir-139, rno-mir-142, rno-mir-150, rno-mir-154, rno-mir-181b-1, rno-mir-181b-2, rno-mir-183, rno-mir-194-1, rno-mir-194-2, rno-mir-200b, rno-mir-212, rno-mir-181a-1, rno-mir-214, rno-mir-296, mmu-mir-376b, mmu-mir-370, mmu-mir-433, rno-mir-433, mmu-mir-466a, rno-mir-383, rno-mir-224, mmu-mir-483, rno-mir-483, rno-mir-370, rno-mir-377, mmu-mir-542, rno-mir-542-1, mmu-mir-494, mmu-mir-20b, mmu-mir-503, rno-mir-494, rno-mir-376b, rno-mir-20b, rno-mir-503-1, mmu-mir-1224, mmu-mir-551b, mmu-mir-672, mmu-mir-455, mmu-mir-490, mmu-mir-466b-1, mmu-mir-466b-2, mmu-mir-466b-3, mmu-mir-466c-1, mmu-mir-466e, mmu-mir-466f-1, mmu-mir-466f-2, mmu-mir-466f-3, mmu-mir-466g, mmu-mir-466h, mmu-mir-504, mmu-mir-466d, mmu-mir-872, mmu-mir-877, rno-mir-466b-1, rno-mir-466b-2, rno-mir-466c, rno-mir-872, rno-mir-877, rno-mir-182, rno-mir-672, mmu-mir-466l, mmu-mir-466i, mmu-mir-466f-4, mmu-mir-466k, mmu-mir-466j, rno-mir-551b, rno-mir-490, rno-mir-1224, rno-mir-504, mmu-mir-466m, mmu-mir-466o, mmu-mir-466c-2, mmu-mir-466b-4, mmu-mir-466b-5, mmu-mir-466b-6, mmu-mir-466b-7, mmu-mir-466p, mmu-mir-466n, mmu-mir-466b-8, rno-mir-466d, mmu-mir-466q, mmu-mir-21b, mmu-mir-21c, mmu-mir-142b, mmu-mir-466c-3, rno-mir-322-2, rno-mir-503-2, rno-mir-466b-3, rno-mir-466b-4, rno-mir-542-2, rno-mir-542-3
Recently, we reported that SR-BI, which delivers the bulk of the cholesterol substrate for steroidogenesis, is regulated by two specific miRNAs, miRNA-125a and miRNA-455, in rat granulosa cells, a mo del mouse Leydig cell line and the rat adrenal gland [19]. [score:2]
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13
[+] score: 1
miR-21, miR-223, miR-455-5p, miR-431 and miR-18 were significantly increased, while miR-138, miR-483 and miR-383 were significantly decreased following nerve transection. [score:1]
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