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2 publications mentioning rno-mir-743a

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-743a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 36
Several miRNAs, such as members of the miR-183-96-182 cluster, miR-741, miR-881, miR-878, miR-743a, miR-743b, miR-465, miR-871, miR-880, are known to be expressed in mouse ESCs and were also expressed in rat PSCs; however, their function in pluripotency induction and regulation has not been directly shown 48– 50. [score:7]
We also analysed the expression of the rno-miR-novel-8 miRNA, rno-miR-sno-57 miRNA, miR-741-3p, and miR-743a-3p, which are upregulated in PSCs during differentiation. [score:6]
Using qPCR, we have shown that members of the miR-741-3p and miR-743a-3p clusters were expressed at high levels in rat ESCs and iPSCs and were downregulated during differentiation. [score:6]
rno-miR-novel-8, rno-homolog-miR-26, and rno-homolog-miR-199 miRNAs were selected from Tier 1, and rno-miR-sno-57 miRNA was selected from Tier 2. In addition, we analysed the expression of miR-741-3p and miR-743a-3p and found that, in accordance with sequencing data, they were highly expressed in rat PSCs. [score:5]
qRT-PCR analysis demonstrated that the rno-miR-novel-8 and rno-miR-sno-57 miRNAs as well as the known miRNAs miR-741-3p and miR-743a-3p were expressed in rat PSCs and absent in rat EFs (Fig.   4a). [score:3]
We found that miR-741-3p, miR-743a-3p, and rno-miR-novel-8 miRNA were expressed in the testis at levels comparable to that in PSCs. [score:3]
A cluster of miRNAs, comprised of miR-463, miR-465, miR-471, miR-741, miR-743a, miR-743b, miR-871, miR-878, miR-880, miR-881, and miR-883, was located on the X chromosome and was expressed at a high level in rat PSCs according to the sequencing data. [score:3]
We found that rat miR-295-3p, miR-741-3p and miR-743a-3p expression was significantly decreased during ESC and iPSC differentiation (Fig.   4b). [score:3]
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2
[+] score: 2
analysis confirmed the direction and amplitude of all miRNA changes with the exception of let-7d, miR-25*, miR-187, miR-291a-5p, miR-292-5p, miR-365, miR-431, miR-487b, miR-615-5p, miR-743a, miR-20b-3p, miR-199a-3p which remained unaltered or showed no statistical significance. [score:2]
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