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5 publications mentioning hsa-mir-1184-1

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-1184-1. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 15
The predicted functional consequence of this variation on the miRNA targetability (using miRanda) revealed that its presence in the binding site leads to the loss of miR-1184 target within Alu, while retaining the other two miRNA targets. [score:7]
The presence of variation (SNP rs921864) adds an additional layer of regulation at the population level by disrupting the target site for miR-1184. [score:4]
The same region also has three miRNA (miR-7156-3p, miR-1184 and miR-1304-3p) target sites, with a potential for cross-talk between these events. [score:3]
The same site harbors binding sites for miR-7156-3p, miR-1184 and miR1304-3p and a SNP (rs921864) with pair-wise F [ST] (YRI-CHB) 0.66, H < −20, iHS 2.46 in YRI and DAF > 0.5. [score:1]
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2
[+] score: 11
Published studies demonstrate that miR-1184 (expressed at the highest levels in our high-risk cohort), is located on the X chromosome but has not been studied in breast cancer. [score:3]
Two-thirds of these miRNAs, hsa-miR-3124-5p (Figure 4A), hsa-miR-1184 (Figure 4B), hsa-miR-4423-3p (Figure 4C), hsa-miR-4529-3p (Figure 4D), hsa-miR-7855 (Figure 4E), and hsa-miR-766-3p (Figure 4G), tended to have lower expression levels in cases, compared with controls. [score:2]
The interaction networks of hsa-miR-3124-5p, hsa-miR-1184, hsa-miR-4423-3p, hsa-miR-4529-3p, hsa-miR-7855-5p, and hsa-miR-4446-3p were identified via Ingenuity Pathway Analysis (IPA, www. [score:1]
The mo dels generated the following risk score formulas: Formula 1: AUC-selected miRNA-mo deled risk score Risk score = (-1.062 x hsa-miR-3124-5p) + (-0.32 x hsa-miR-1184) + (-0.33 x hsa-miR-4423-3p) + (0.621 x hsa-miR-4529-3p) + (-0.626 x hsa-miR-7855-5p) + (0.359 x hsa-miR-4446-3p) Formula 2: ANOVA-selected miRNA-mo deled risk score Risk score = (-0.274 x hsa-miR-1184) + (-1.305 x hsa-miR-766-3p) + (-0.393 x hsa-miR-4423-3p) + (0.601 x hsa-miR-4727-3p) + (0.229 x hsa-miR-208a-5p) These formula-generated risk scores were applied to miRNA levels from each case and control for discriminatory power. [score:1]
The mo dels generated the following risk score formulas: Formula 1: AUC-selected miRNA-mo deled risk score Risk score = (-1.062 x hsa-miR-3124-5p) + (-0.32 x hsa-miR-1184) + (-0.33 x hsa-miR-4423-3p) + (0.621 x hsa-miR-4529-3p) + (-0.626 x hsa-miR-7855-5p) + (0.359 x hsa-miR-4446-3p) Formula 2: ANOVA-selected miRNA-mo deled risk score Risk score = (-0.274 x hsa-miR-1184) + (-1.305 x hsa-miR-766-3p) + (-0.393 x hsa-miR-4423-3p) + (0.601 x hsa-miR-4727-3p) + (0.229 x hsa-miR-208a-5p)These formula-generated risk scores were applied to miRNA levels from each case and control for discriminatory power. [score:1]
The 6-miRNA signature of miR-3124-5p, miR-1184, miR-4423-3p, miR-4529-3p, miR-7855-5p, and miR-4446-3p performs better than current mo dels with an AUC of 0.896 (CI 0.804-0.988) (see Figure 3). [score:1]
Three miRNAs (hsa-miR-1184, hsa-miR-4423-3p, and hsa-miR-7855-5p) were common to both the AUC and ANOVA sets. [score:1]
Circulating levels of miR-1184 are reported to be increased in patients with prostate cancer [42], but were decreased in breast cancer cases in our cohort. [score:1]
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3
[+] score: 8
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-21, hsa-mir-23a, hsa-mir-30a, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-196a-1, hsa-mir-148a, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-181a-2, hsa-mir-181b-1, hsa-mir-181c, hsa-mir-196a-2, hsa-mir-210, hsa-mir-181a-1, hsa-mir-218-1, hsa-let-7g, hsa-let-7i, hsa-mir-23b, hsa-mir-30b, hsa-mir-128-1, hsa-mir-145, hsa-mir-191, hsa-mir-181b-2, hsa-mir-128-2, hsa-mir-30c-1, hsa-mir-99b, hsa-mir-296, hsa-mir-30e, hsa-mir-361, hsa-mir-337, hsa-mir-148b, hsa-mir-196b, hsa-mir-425, hsa-mir-20b, hsa-mir-486-1, hsa-mir-488, hsa-mir-181d, hsa-mir-498, hsa-mir-519c, hsa-mir-520a, hsa-mir-526b, hsa-mir-520d, hsa-mir-506, hsa-mir-92b, hsa-mir-608, hsa-mir-617, hsa-mir-625, hsa-mir-641, hsa-mir-1264, hsa-mir-1271, bta-let-7f-2, bta-mir-103-1, bta-mir-148a, bta-mir-21, bta-mir-30d, bta-mir-128-1, bta-mir-145, bta-mir-181a-2, bta-mir-30b, bta-mir-181b-2, bta-mir-20b, bta-mir-30e, bta-mir-92a-2, bta-let-7d, bta-mir-148b, bta-mir-181c, bta-mir-191, bta-mir-210, bta-mir-23a, bta-mir-361, bta-mir-425, bta-let-7g, bta-mir-30a, bta-let-7a-1, bta-let-7f-1, bta-mir-30c, bta-let-7i, bta-mir-23b, bta-let-7a-2, bta-let-7a-3, bta-let-7b, bta-let-7c, bta-let-7e, bta-mir-103-2, bta-mir-99b, hsa-mir-890, hsa-mir-888, hsa-mir-889, hsa-mir-938, hsa-mir-1203, hsa-mir-1204, hsa-mir-1265, hsa-mir-103b-1, hsa-mir-103b-2, bta-mir-128-2, bta-mir-181d, bta-mir-196a-2, bta-mir-196a-1, bta-mir-196b, bta-mir-218-1, bta-mir-296, bta-mir-30f, bta-mir-486, bta-mir-488, bta-mir-92a-1, bta-mir-92b, bta-mir-1271, bta-mir-181a-1, bta-mir-181b-1, bta-mir-148c, hsa-mir-1184-2, hsa-mir-1184-3, hsa-mir-486-2, bta-mir-1264, bta-mir-148d
Moreover, miR-361-5p, miR-1184 and miR-218-1* were the top among the upregulated miRNAs while miR-1265, miR-20b*, miR-520d-5p and miR-506 were the top among the downregulated miRNAs in the SE animals. [score:7]
Among these, miR-938, miR-519c-3p, miR-1265, miR-498 and miR-488 were exclusively detected only in HE animals and 10 miRNAs including miR-608, miR-625*, miR-218-1*, miR-888*, miR-1184 and miR-1264 were detected only in SE and CE animal groups. [score:1]
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4
[+] score: 3
Other miRNAs from this paper: hsa-mir-619, hsa-mir-1184-2, hsa-mir-1184-3
It was observed, that hsa-miR-619-5p and hsa-miR-1184 microRNA expression significantly increased in prostatic cancer. [score:3]
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5
[+] score: 3
The microRNA intersections in three softwares suggested that 64 microRNAs (e. g., hsa-miR-575, hsa-miR-149-3p, hsa-miR-382-5p, hsa-miR-516a-3p, hsa-miR-1184, hsa-miR-1261, hsa-miR-3127-5p, hsa-miR-3127-5p, hsa-miR-4649-3p) could be highly related to GAPLINC, and therefore, could be selected as candidates (shown by Venn graph, Figure 4A). [score:1]
We selected six microRNAs as superior candidates (hsa-miR-575, hsa-miR-149-3p, hsa-miR-382-5p, hsa-miR-516a-3p, hsa-miR-1184, hsa-miR-1261) according to their comprehensive assessments and constructed a co-action network graph. [score:1]
We found 64 microRNAs may be the interactions of GAPLINC, including hsa-miR-575, hsa-miR-149-3p, hsa-miR-382-5p, hsa-miR-516a-3p, hsa-miR-1184, hsa-miR-1261, hsa-miR-3127-5p, hsa-miR-4649-3p, and so on. [score:1]
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