sort by

3 publications mentioning hsa-mir-1322

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-1322. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 50
Other miRNAs from this paper: hsa-mir-3960
Target genes for miR-1322 were determined using the MirTarget program [6], which was developed in our laboratory. [score:5]
For example, downregulation of ECRG2 and TCA3 is associated with squamous cell carcinoma of the esophagus (ESCC) via miR-1322 [12]. [score:4]
Therefore, expression of these genes can be controlled extensively by miR-1322. [score:3]
Various paralogous genes are targets for miR-1322. [score:3]
We found that miR-1322 has 2,264 binding sites on 1,058 target mRNAs with a Δ G/Δ G [m] ratio of 85% or more. [score:3]
The presence of multiple regions containing miR-1322 binding sites in MAMLD1, MAML2, and MAML3 genes shows a strong dependence of their expression via miR-1322. [score:3]
Consequently, these untranslated regions have an increased probability of binding with miR-1322. [score:3]
We studied the arrangement and evolution of miR-1322 binding sites in genes involved in disease. [score:3]
Unfortunately, experimental data on miR-1322 binding sites are insufficient; however, some previous studies confirm the high efficacy of the predictions of the MirTarget program developed in our laboratory. [score:3]
The relationship between paralogous and orthologous mRNAs of the MAML gene family was considered an example of adaptation of gene expression to the action of miR-1322. [score:2]
Discussed in this paper is miR-1322 which also contains multiple sites in CDSs. [score:1]
miR-1322 has a length of 19 nucleotides (nt) and a GC-content of 53%. [score:1]
The Δ G/Δ G [m] ratio for all miR-1322 binding sites of the ANO2 gene is 95.8%. [score:1]
The conservation of binding sites relative to the adjacent regions of CDSs is shown in Figure 2. It is important to establish the presence of miR-1322 binding sites for paralogous and orthologous mRNA sequences. [score:1]
The arranged nucleotide sequences of the CDSs contain binding sites for miR-1322 (Figure 1). [score:1]
Of those, 160 miR-1322 binding sites are located in the 3′ UTRs of 130 genes, 215 binding sites are located in the 5′ UTRs of 109 genes, and 1,889 binding sites are located in the CDSs of 819 genes. [score:1]
Two regions contain multiple miR-1322 binding sites in MAMLD1 (Figure 3). [score:1]
Oligonucleotides containing CAG repeats represent the miR-1322 binding site of the mRNA that encoded a long polyglutamine sequence in the corresponding protein. [score:1]
The maximum free energy of miR-1322 binding with mRNAs is −101.9 kJ/mole. [score:1]
Nucleotide sequences of human mature miR-1322 were downloaded from the miRBase database (http://mirbase. [score:1]
The CDS of the human MAML3 gene has three regions that contain miR-1322 binding sites, and it encodes oligopeptides containing 21, 18, and eight glutamine residues. [score:1]
These data indicate the importance of conserved nucleotide sequences of miR-1322 binding sites and not only the amino acid sequence corresponding to oligopeptides of the encoded protein. [score:1]
The presence of multiple miR-1322 binding sites in MAMLD1, MAML2, and MAML3 demonstrates their interactions. [score:1]
miR-1322 binding sites in orthologous MAML mRNAs are highly conserved. [score:1]
Features of miR-1322-3p Binding Sites. [score:1]
The CDS of the human MAML2 gene also has two regions with miR-1322 binding sites and encodes oligopeptides containing 47 and 27 glutamine residues (Figure 4). [score:1]
The serum level of miR-1322 is a potential diagnostic biomarker for squamous cell carcinoma of the esophagus [12]. [score:1]
It is possible that changes in the dependence of the interactions between miR-1322 and MAMLD1, MAML2, and MAML3 are interconnected. [score:1]
[1 to 20 of 28 sentences]
[+] score: 3
org/) [20] revealed that all three SNPs are located within potential miRNA target sites: rs17592236 (miR-137), rs4946936 (miR-1182), rs4503258 (miR-1322). [score:3]
[1 to 20 of 1 sentences]
[+] score: 1
Some miRNAs were not detected in a variety of liver cancer cells such as miR-596, miR-548i-3, miR-597, miR-4286, miR-1322, miR-598 and miR-548v. [score:1]
[1 to 20 of 1 sentences]