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8 publications mentioning hsa-mir-1469

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-1469. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 38
Table 1 Nine miRNAs selected after rescreening miRNA_miRBase-18th Fold change (3/1) Direction hsa-miR-1469 1.262138297 Upregulated hsa-miR-762 1.200592588 Upregulated hsa-miR-338-5p 2.129779884 Upregulated hsa-miR-3173-3p 1.226251386 Upregulated hsa-miR-4467 1.284049958 Upregulated hsa-miR-3940-5p 1.336691618 Upregulated hsa-miR-3195 1.376221162 Upregulated hsa-miR-3621 1.273270254 Upregulated hsa-miR-663a 1.221943009 Upregulated As miR-338-5p demonstrated the highest upregulation by ACBP-3, it was selected for validation by qRT-PCR. [score:32]
The differentially expressed miRNAs detected in two chips did not overlap, so, after multiple rescreening processes, nine miRNAs significantly upregulated by ACBP-3 (P < 0.05) were selected for further analysis: hsa-miR-1469, hsa-miR-762, hsa-miR-338-5p, hsa-miR-3173-3p, hsa-miR-4467, hsa-miR-3940-5p, hsa-miR-3195, hsa-miR-3621, and hsa-miR-663a (Table  1). [score:6]
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2
[+] score: 9
Other miRNAs from this paper: hsa-mir-204, hsa-mir-184, hsa-mir-4279
The AGE‐modified BME (without TGFβ2 treatment) showed significant upregulations in the mRNA levels of MMP2, miR4279, and miR1469, with minor statistically insignificant increases in αSMA, CTGF, and integrin αV. [score:4]
αSMA, MMP2, CTGF, integrin αV, integrin α5, integrin β1, miR4279, and miR1469 have been shown to be upregulated by TGFβ2 during the EMT of HLE cells (Dawes et al., 2007; Wang et al., 2013; Mamuya et al., 2014). [score:4]
Similarly, the mRNA levels of CTGF, integrin αV, MMP‐2, miR1469, and miR4279 were significantly higher (P < 0.0005) in the cells cultured on AGE‐modified BME than in the cells cultured on unmodified BME. [score:1]
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3
[+] score: 7
There is at least one putative target for each microRNA at days 0 and 7, instead only 12 out of 16 miRs have predicted targets at day 14, because 4 miRs (miR-1181, miR-1288, miR-1914, miR-1469) are missing in the prediction target databases. [score:7]
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4
[+] score: 7
logFC p-value B-statistic microRNA 0.98 3.53E-08 9.07 hsa-miR-1244 0.74 2.34E-07 7.34 hsa-miR-494 0.45 6.83E-07 6.34 hsa-miR-1979 0.31 3.97E-06 4.66 hsa-miR-1826 0.77 9.14E-06 3.85 hsa-miR-1281 −0.31 1.13E-05 3.65 hsa-miR-202 −0.37 1.14E-05 3.64 hsa-miR-4284 −0.49 1.70E-05 3.25 hsa-miR-221-star −0.89 6.51E-05 1.94 hsa-miR-3172 −0.63 9.48E-05 1.57 hsa-miR-548a-3p −0.43 1. 02E-04 1.49 hsa-miR-1272 −0.34 1.29E-04 1.27 hsa-miR-15a −0.40 1.59E-04 1.06 hsa-miR-3152 −0.22 2.56E-04 0.59 hsa-miR-142–5p 0.24 3.03E-04 0.43 hsa-miR-4270 −0.29 3.27E-04 0.35 hsa-miR-1910 −0.42 3.29E-04 0.35 hsa-miR-34a-star −0.18 3.78E-04 0.21 hsa-miR-381 −0.30 4.10E-04 0.13 hsa-miR-450b-5p 0.30 4.34E-04 0.08 hsa-miR-1469 We also looked for differentially expressed miRNAs (BH adjusted p < 0.05) that may target differentially expressed mRNAs (BH adjusted p < 0.05). [score:7]
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5
[+] score: 6
Other miRNAs from this paper: mmu-mir-130b, hsa-mir-130b, hsa-mir-1468
showed that miR-1468 overexpression inhibited, while miR-1469 knockdown increased the luciferase activity of wild-type (wt) CITED2 or UPF1 3’-UTR but not the mutant (mt) CITED2 or UPF1 3’-UTR (P < 0.05, Fig. 4b). [score:6]
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6
[+] score: 3
However, we could not determine the changes in miR-1469 because no TaqMan miRNA assay kit was available; nor miR-299-5p, possibly because it was only expressed at low levels. [score:2]
Based on the criteria described in the Method (fold-change >1.5, coefficient of variation <50%, and high Hy3 signal >1.5× the median signal), only four miRNAs (miR-149*, miR-299-5p, miR-1469 and miR-1908) were selected. [score:1]
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7
[+] score: 1
miRNAs were normalized to the average of three different miRNAs miR-147, miR-574-3p and miR-1469. [score:1]
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8
[+] score: 1
The maximum probability (approximately 0.2) was obtained for the same pair (TMSB10 and hsa-miR-1469) from each sample. [score:1]
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