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2 publications mentioning csa-let-7b

Open access articles that are associated with the species Ciona savignyi and mention the gene name let-7b. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 17
Therefore, we were not surprised to find the let-7 homolog expressed in the adult tissue of C. intestinalis. [score:3]
For example, let-7 is highly expressed in adult tissue of C. elegans, D. melanogaster, and vertebrates [23]. [score:3]
Our method predicted let-7, miR-7, and miR-126, as well as 11 other conserved miRNA families. [score:1]
Their published prediction of 41 miRNA precursor sequences overlapped with ours by just one microRNA, let-7. In a subsequent study [37], a clustering approach was used with the Ciona non-coding RNA candidate sequences. [score:1]
When hybridizing against the probes for the miR-72 and let-7 Ciona homologs, the C. intestinalis lanes showed strong positive signals. [score:1]
Figures 2 and 3 show the mfold program's text and graphical output for the putative miR-72 and let-7 for Ciona and C. elegans. [score:1]
For the predicted let-7 and miR-72 Ciona miRNA homologs, oligonucleotides were designed as probes for both the top and bottom strands of the hairpin structure. [score:1]
In both the let-7 and miR-72 homologs, no hybridization to the anti-sense strand occurred. [score:1]
Anti-sense (AS) probes were tested for let-7 and miR-72. [score:1]
The C. elegans lanes showed a weak response to the Ciona miR-72 homolog probe, and no response to the Ciona let-7 homolog probe. [score:1]
Similarly, since the Ciona let-7 sequence contained 2 alignment gaps in the middle section the C. elegans sequence, we did not expect to see hybridization. [score:1]
To validate the strand polarity of the predicted mature miRNAs, we performed the Northern blot analysis with sense and anti-sense probes for the top and bottom strands of the let-7 and miR-72 C. intestinalis homolog predictions. [score:1]
By this method, the authors predicted 58 miRNAs, of which only let-7, miR-7, miR-124, and miR-126 coincided with known miRNAs. [score:1]
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[+] score: 1
Eighteen families evolved during the origin of Nephrozoa (miR-1, 7, 8/200, 25/92, 31, 34, 46/281, 96, 124, 125, 133, 153, 183, 184, 219, 281, 375, and let-7). [score:1]
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