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3 publications mentioning mml-mir-302a

Open access articles that are associated with the species Macaca mulatta and mention the gene name mir-302a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 22
On the other hand, miR-302 can enhance reprogramming by accelerating mesenchymal-to-epithelial translation (MET) [30] and suppressing some epigenetic regulators [23]. [score:6]
Nanog, Oct3/4, Sox2 and Rex1 are upstream regulators of the miR-302 cluster promoter [26], miR-302a regulate ESCs cell cycle by repressing cyclin D1 [27], and miR-302 impair early differentiation by repress NR2F2 [28] and Lefty [29] at the post-transcriptional level. [score:3]
We also analyzed miRNA cluster expression patterns and the results revealed that miRNAs from miR-302 cluster, miR-182/miR-183/miR-96 cluster and miR-143/miR-145 cluster were the most rpESCs enriched miRNAs. [score:3]
For miRNAs which had a very high expression level(>10000 reads TPM) in both parthenogenetic and IVF rhesus monkey ESCs, members of mir-302 cluster, miR-106b-25 cluster have important roles in maintaining of pluripotency. [score:3]
This phenomenon recently observed also in mouse and human parthenogenetic ESCs [1], [21], [22], due to homologous crossing-over and recombination during meiosis I. In our two rpESCs, mir-302 cluster had a very high expression level, consisting with previous studies that mir-302 cluster was high-riched in human ESCs [12]– [18]. [score:3]
Recently, the roles of mir-302 cluster in regulation of ESCs pluripotency have been clarified on some extent. [score:2]
Our previous research suggested that rhesus monkey ESCs from in vitro fertilization (IVF) blastocysts also share a unique miRNAs set, miR-302 cluster, which were reported to be highly enriched in human ESCs, were the most rhesus monkey ESCs enriched miRNAs [19]. [score:1]
Intriguingly, mir-302 cluster can reprogram cancer or somatic cells into iPS [23]– [25] revealed that mir-302 cluster had important roles in maintaining pluripotency of pluripotent cells. [score:1]
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[+] score: 6
Instead, the miR-302 cluster was the highest expressed in human and rhesus macaque [14, 30, 31], indicating the functional divergence of stemness miRNA clusters in primate lineages. [score:3]
MiR-290-295 and miR-302 clusters are transcriptionally regulated by Oct-4/Sox2 [29]. [score:2]
The miR-290-295 cluster contains multiple mature miRNAs with seed sequences similar or identical to those in the miR-302 cluster [6]. [score:1]
[1 to 20 of 3 sentences]
[+] score: 1
The well-known ESC-enriched miRNAs including miR-302a, miR-302b, miR-302c, miR-302d, miR-367, miR-371-5p, miR-371-3p, miR-372, and miR-373 were in our list, indicating the liability of our data. [score:1]
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