sort by

3 publications mentioning crm-let-7

Open access articles that are associated with the species Caenorhabditis remanei and mention the gene name let-7. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 22
Other miRNAs from this paper: cel-let-7, cbr-let-7
Expression of let-7 RNA is temporally regulated with robust expression in the fourth larval and adult states. [score:6]
A growing body of evidence suggests that the human let-7 expression is misregulated in many human cancers, and restoration of let-7 expression may be a useful therapeutic option in cancers (Boyerinas et al. 2010). [score:6]
It would be interesting to see whether the other two predicted modules drive let-7 expression in those cells. [score:3]
let-7 is also expressed in the anchor cell at L3 and in the distal tip cells at the adult stage (Esquela-Kerscher et al. 2005). [score:3]
Currently there is only one miRNA, let-7, whose promoter region sequences has been dissected to identify regulatory sequences. [score:2]
Figure 3Comparison between predicted CRM with experimentally defined CRM in intron regions and in miRNA let-7 promoter region. [score:1]
The let-7 family of microRNAs, first discovered in C. elegans, is functionally conserved from worms to humans. [score:1]
[1 to 20 of 7 sentences]
[+] score: 2
Other miRNAs from this paper: cel-let-7, cbr-let-7, ppc-let-7, bma-let-7, asu-let-7, cbn-let-7
VIG-1, the C. elegans ortholog of Drosophila VASA intronic gene which regulates transition between larval and adult cellular fates though interaction with the let-7 miRNA [73], was identified in five of our eight species. [score:2]
[1 to 20 of 1 sentences]
[+] score: 1
Because of this flux in miRNA recognition, we refer to miRNAs by their name when they are present in miRBase (e. g., lin-4, let-7, mir-1) and use previous authors’ nomenclature for miRNA names when they are absent from miRBase (e. g., block453) (de Wit et al. 2009). [score:1]
[1 to 20 of 1 sentences]