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2 publications mentioning rno-mir-666

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-666. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 18
Other miRNAs from this paper: rno-mir-326, rno-mir-330, rno-mir-485, rno-mir-761
Target prediction and GO analysis of miR-326-3p/330-5p, miR-485-5p (miR-485-5p/1698/1703/1962), miR-666-3p and miR-761-5p showed enrichment for terms associated with synaptic transmission, plasticity, neurotransmitter synthesis and vesicular release, in both miRNA targets (figure 4 a) and GO terms (figure 4 b and table 3; and the electronic supplementary material, table S2). [score:5]
Several of the corresponding miRNAs, including miR-326/miR-330, miR-485, miR-666 and miR-761 were found to be developmentally regulated in the hippocampus. [score:3]
Moreover, miR-485 and miR-666 are intronic miRNAs that are part of the large Dlk1-Dio3 imprinted locus [52, 53] containing at least 53 miRNAs expressed in the CNS [54]. [score:3]
Ingenuity pathway analysis was performed on predicted targets of miR-326-3p/miR-330-5p, miR-485-5p, miR-666-3p and miR-761 using the T argetS can v. 6.2 algorithm [49– 51]. [score:3]
We found that four of the discovered motifs (figure 3 a) in the destabilized gene set corresponded to seed domains of miRNAs miR-326-3p/miR-330-5p, miR-485-5p, miR-666-3p and miR-761. [score:1]
Of the miRNA motifs that were identified, motifs corresponding to seed domains for miR-666-3p and miR-485-5p were over-represented in the variable-width motif set (electronic supplementary material, figure S2). [score:1]
miR-666-3p top canonical pathways. [score:1]
Transcript levels for miR-326-3p, miR-485-5p, miR-666-3p and miR-761 increased by threefold to 12-fold by 14 days post parturition (figure 4 c) (n = 3 animals per time point). [score:1]
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2
[+] score: 1
Several miRNAs including rno-miR-582, rno-miR-666-3p, and rno-miR-2985-3p were not detected in our study. [score:1]
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