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6 publications mentioning hsa-mir-4290

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-4290. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 7
The expression profile of infected and uninfected cells was evaluated using a miRNA microarray, and 16 miRNAs were reported to be up-regulated (miR-4290, miR-4279, miR-625*, miR-let-7e, miR-1290, miR-33a, miR-3686, miR-378, miR-1246, miR-767-5p, miR-320c, miR-720, miR-491-3p, miR-3647, miR-451 and miR-4286) and 4 down-regulated (miR-106b, miR-20a, miR-30b and miR-3653) during dengue infection. [score:7]
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2
[+] score: 7
For top 10 upregulated microRNAs (hsa-miR-197-3p, hsa-miR-574-3p, hsa-miR-885-5p, hsa-miR-483-3p, hsa-miR-1281, hsa-miR-328, hsa-miR-4254, hsa-miR-4290, hsa-miR-1825, hsa-miR-766-3p), we included those have been shown to be deregulated in cancer, and have either expression data or functional studies in stem cells. [score:7]
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3
[+] score: 7
Additionally, miR-4290 is present in exosomes (Leidinger et al., 2014) but not in any blood cell type or whole blood, suggesting that ectopic or increased expression of this miRNA could be a candidate biomarker for immune-related diseases. [score:5]
The risk allele (T) of miRSNP rs60474474 is predicted to disrupt the binding of miR-4290. [score:1]
Both miRSNPs were predicted to alter miRNA binding sites in the 3′ UTR of the PTPN2 mRNA: miRSNP rs60474474 disrupts the binding site of miR-4290 (NBC Score = 0.99) and miRSNP rs45450798 creates a new binding site for miR-4531 (NBC Score = 0.73) (Table 2). [score:1]
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4
[+] score: 5
With the exception of the patient S2, two groups of miRNAs can be observed, one group in which the expression is lower in the patients with short-OS (miR-211, miR-1207-3p, miR-326, miR-197, let-7b*, miR-1296, miR-4290) and one group that has an opposite expression profile (miR-4321, miR-3610, miR-1914*). [score:5]
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5
[+] score: 1
The respective 16 markers include hsa-miR-1299, hsa-miR-3124, hsa-miR-4290, hsa-miR-2278, hsa-miR-32*, hsa-miR-3149, hsa-miR-877*, hsa-miR-584, hsa-miR-3148, hsa-miR-122, hsa-miR-718, hsa-miR-670, hsa-miR-3680*, hsa-miR-193b*, hsa-miR-3911 and hsa-miR-1228* (see Figure  4). [score:1]
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6
[+] score: 1
We found: miR-4290, miR-1281, miR-4716-5p, miR-483-3p and miR-877-3p containing almost only UC nucleotides and miR-6124, miR-483-5p, miR-4271, miR-4644, miR-4716-3p and miR-1234-5p purine-rich. [score:1]
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