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6 publications mentioning hsa-mir-4290Open access articles that are associated with the species Homo sapiens and mention the gene name mir-4290. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary. |
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Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-20a, hsa-mir-21, hsa-mir-33a, hsa-mir-96, hsa-mir-99a, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-196a-1, hsa-mir-208a, hsa-mir-181a-2, hsa-mir-181c, hsa-mir-196a-2, hsa-mir-181a-1, hsa-mir-221, hsa-mir-223, hsa-let-7g, hsa-let-7i, hsa-mir-1-2, hsa-mir-15b, hsa-mir-30b, hsa-mir-140, hsa-mir-142, hsa-mir-126, hsa-mir-146a, hsa-mir-149, hsa-mir-150, hsa-mir-184, hsa-mir-1-1, hsa-mir-155, hsa-mir-106b, hsa-mir-301a, hsa-mir-130b, hsa-mir-30e, hsa-mir-374a, hsa-mir-378a, hsa-mir-324, hsa-mir-20b, hsa-mir-429, hsa-mir-451a, hsa-mir-491, hsa-mir-146b, hsa-mir-202, hsa-mir-512-1, hsa-mir-512-2, hsa-mir-532, hsa-mir-92b, hsa-mir-625, hsa-mir-767, hsa-mir-320c-1, hsa-mir-1271, hsa-mir-378d-2, hsa-mir-301b, hsa-mir-937, hsa-mir-1204, hsa-mir-1290, hsa-mir-1246, hsa-mir-1268a, hsa-mir-1307, hsa-mir-320c-2, hsa-mir-2116, hsa-mir-378b, hsa-mir-3178, hsa-mir-3195, hsa-mir-378c, hsa-mir-4279, hsa-mir-4286, hsa-mir-3686, hsa-mir-1268b, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-451b, hsa-mir-378j
The expression profile of infected and uninfected cells was evaluated using a miRNA microarray, and 16 miRNAs were reported to be up-regulated (miR-4290, miR-4279, miR-625*, miR-let-7e, miR-1290, miR-33a, miR-3686, miR-378, miR-1246, miR-767-5p, miR-320c, miR-720, miR-491-3p, miR-3647, miR-451 and miR-4286) and 4 down-regulated (miR-106b, miR-20a, miR-30b and miR-3653) during dengue infection.
[score:7]
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Other miRNAs from this paper: hsa-mir-26a-1, hsa-mir-26b, hsa-mir-197, hsa-mir-203a, hsa-mir-223, hsa-mir-200b, hsa-mir-15b, hsa-mir-142, hsa-mir-150, hsa-mir-185, hsa-mir-200c, hsa-mir-106b, hsa-mir-200a, hsa-mir-26a-2, hsa-mir-363, hsa-mir-328, hsa-mir-425, hsa-mir-483, hsa-mir-494, hsa-mir-574, hsa-mir-766, hsa-mir-885, hsa-mir-1281, hsa-mir-1825, hsa-mir-4254, hsa-mir-203b
For top 10 upregulated microRNAs (hsa-miR-197-3p, hsa-miR-574-3p, hsa-miR-885-5p, hsa-miR-483-3p, hsa-miR-1281, hsa-miR-328, hsa-miR-4254, hsa-miR-4290, hsa-miR-1825, hsa-miR-766-3p), we included those have been shown to be deregulated in cancer, and have either expression data or functional studies in stem cells.
[score:7]
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Other miRNAs from this paper: hsa-mir-365a, hsa-mir-326, hsa-mir-584, hsa-mir-628, hsa-mir-1207, hsa-mir-1910, hsa-mir-3136, hsa-mir-3661, hsa-mir-3918, hsa-mir-4518, hsa-mir-4531, hsa-mir-4741, hsa-mir-4763, hsa-mir-7155
Additionally, miR-4290 is present in exosomes (Leidinger et al., 2014) but not in any blood cell type or whole blood, suggesting that ectopic or increased expression of this miRNA could be a candidate biomarker for immune-related diseases.
[score:5]
The risk allele (T) of miRSNP rs60474474 is predicted to disrupt the binding of miR-4290.
[score:1]
Both miRSNPs were predicted to alter miRNA binding sites in the 3′ UTR of the PTPN2 mRNA: miRSNP rs60474474 disrupts the binding site of miR-4290 (NBC Score = 0.99) and miRSNP rs45450798 creates a new binding site for miR-4531 (NBC Score = 0.73) (Table 2).
[score:1]
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Other miRNAs from this paper: hsa-let-7b, hsa-mir-21, hsa-mir-30a, hsa-mir-105-1, hsa-mir-105-2, hsa-mir-197, hsa-mir-34a, hsa-mir-187, hsa-mir-196a-2, hsa-mir-204, hsa-mir-211, hsa-mir-219a-1, hsa-mir-127, hsa-mir-219a-2, hsa-mir-34b, hsa-mir-34c, hsa-mir-337, hsa-mir-326, hsa-mir-452, hsa-mir-1296, hsa-mir-766, hsa-mir-1200, hsa-mir-1207, hsa-mir-1914, hsa-mir-4321, hsa-mir-3610, hsa-mir-219b
With the exception of the patient S2, two groups of miRNAs can be observed, one group in which the expression is lower in the patients with short-OS (miR-211, miR-1207-3p, miR-326, miR-197, let-7b*, miR-1296, miR-4290) and one group that has an opposite expression profile (miR-4321, miR-3610, miR-1914*).
[score:5]
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Other miRNAs from this paper: hsa-mir-17, hsa-mir-32, hsa-mir-106a, hsa-mir-181b-1, hsa-mir-199b, hsa-mir-223, hsa-mir-122, hsa-mir-143, hsa-mir-145, hsa-mir-146a, hsa-mir-150, hsa-mir-155, hsa-mir-181b-2, hsa-mir-106b, hsa-mir-363, hsa-mir-340, hsa-mir-342, hsa-mir-151a, hsa-mir-338, hsa-mir-424, hsa-mir-193b, hsa-mir-582, hsa-mir-584, hsa-mir-151b, hsa-mir-670, hsa-mir-877, hsa-mir-1228, hsa-mir-1299, hsa-mir-2278, hsa-mir-718, hsa-mir-3124, hsa-mir-3148, hsa-mir-3149, hsa-mir-3663, hsa-mir-3680-1, hsa-mir-3911, hsa-mir-3680-2
The respective 16 markers include hsa-miR-1299, hsa-miR-3124, hsa-miR-4290, hsa-miR-2278, hsa-miR-32*, hsa-miR-3149, hsa-miR-877*, hsa-miR-584, hsa-miR-3148, hsa-miR-122, hsa-miR-718, hsa-miR-670, hsa-miR-3680*, hsa-miR-193b*, hsa-miR-3911 and hsa-miR-1228* (see Figure 4).
[score:1]
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Other miRNAs from this paper: hsa-let-7b, hsa-mir-32, hsa-mir-147a, hsa-mir-483, hsa-mir-493, hsa-mir-520h, hsa-mir-539, hsa-mir-545, hsa-mir-574, hsa-mir-660, hsa-mir-877, hsa-mir-1228, hsa-mir-1234, hsa-mir-1238, hsa-mir-1277, hsa-mir-1281, hsa-mir-4271, hsa-mir-3620, hsa-mir-4644, hsa-mir-4649, hsa-mir-4716, hsa-mir-6124
We found: miR-4290, miR-1281, miR-4716-5p, miR-483-3p and miR-877-3p containing almost only UC nucleotides and miR-6124, miR-483-5p, miR-4271, miR-4644, miR-4716-3p and miR-1234-5p purine-rich.
[score:1]
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