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5 publications mentioning hsa-mir-3605

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-3605. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 23
Other miRNAs from this paper: hsa-mir-149, hsa-mir-5001
Therefore, we inferred that the down-regulation of hsa-miR-3605-5p mediates the high expression of SCARB2. [score:6]
We also found that the miRNA hsa-miR-3605-5p, which targets the SCARB2 gene, was down-regulated in CVA16-infected cells. [score:6]
Based on correlation analysis of miRNAs and genes, we speculated that the high expression of SCARB2 is modulated by down-regulation of miRNA has-miR-3605-5p. [score:6]
SCABR2 serving as a cellular receptor plays an important role in co-infections of EV71 and CVA16, and has-miR-3605-5p regulates the high expression of SCARB2. [score:4]
The miRNA hsa-miR-3605-5p plays an important role in the processes of metal ion transport, monovalent inorganic cation transport, intracellular transport and transmembrane transport. [score:1]
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2
[+] score: 18
Only two of the differentially expressed miRNAs in our study are directly processed by the spliceosome (miR-3605-5p and miR-4728-5p), and we found an intergenic miRNA (let-7i-5p) to be significantly downregulated in the SF3B1 mutated samples. [score:7]
Host Gene Transcribed direction LFC Tumor Suppressor P-value let-7c-5p Canonical 21 MIR99AHG Same −2.13 Yes 0.001 let-7b-5p Canonical 22 MIRLET7BHG Same −2.49 Yes 0.002 let-7f-5p let-7f-1 let-7f-2 −1.4 Yes 0.004 Canonical 9 JB153432 Same Canonical x HUWE1 Same let-7a-5p let-7a-1 let-7a-2 let-7a-3 −1.67 Yes 0.005 Canonical 9 JB153432 Same Canonical 11 MIRLET100 Same Canonical 22 MIRLET7BHG Same hsa-miR-423-5p Canonical 17 NSRP1 Same −1.66 Yes 0.007 hsa-miR-103a-3p hsa-miR-103a-1 hsa-miR-103a-2 −0.87 Yes 0.009 Canonical 5 PANK3 Same Canonical 20 PANK2 Same hsa-miR-26b-5p Canonical 2 CTDSP1 Same −2.24 Yes 0.011 let-7i-5p Canonical 12 No host gene N/A −1.09 Yes 0.011 hsa-miR-15a-5p Canonical 13 DLEU2 Same −1.18 Unknown 0.011 hsa-miR-3605-5p Mirtron 1 PHC2 Same −1.23 Unknown 0.030 hsa-miR-192-5p Canonical 11 AB429224 Same −0.84 Yes 0.047 Abbreviations, Chr: Chromosome, LFC: log2 fold change. [score:4]
Except for one mirtron (miR-3605-5p), all of these miRNAs were intragenic canonical miRNAs downregulated in the mutated samples. [score:4]
When considering all mutated samples together, eight miRNAs (let-7c-5p, let-7a-5p, let-7b-5p, miR-423-5p, let-7f-5p, miR-26b-5p, miR-15a-5p, and miR-3605-5p) were differentially expressed compared to wild-type samples. [score:2]
Most of these were canonical miRNAs, with the exception of one mirtron (miR-3605-5p). [score:1]
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3
[+] score: 7
It has been only observed in patients with myelodysplastic syndrome that SF3B1 and SRFS2 mutations are associated with a downregulated expression of miRNAs derived from the putative 5′-tailed mirtrons hsa-miR-3605-5p and hsa-miR-4728-5p, respectively [5]. [score:7]
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4
[+] score: 3
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-30a, hsa-mir-32, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-196a-1, hsa-mir-30d, hsa-mir-196a-2, hsa-let-7g, hsa-let-7i, hsa-mir-191, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-149, hsa-mir-200c, hsa-mir-425, hsa-mir-505, hsa-mir-548a-1, hsa-mir-548b, hsa-mir-548a-2, hsa-mir-548a-3, hsa-mir-548c, hsa-mir-625, hsa-mir-548d-1, hsa-mir-548d-2, hsa-mir-548e, hsa-mir-548j, hsa-mir-548k, hsa-mir-548l, hsa-mir-548f-1, hsa-mir-548f-2, hsa-mir-548f-3, hsa-mir-548f-4, hsa-mir-548f-5, hsa-mir-548g, hsa-mir-548n, hsa-mir-548m, hsa-mir-548o, hsa-mir-548h-1, hsa-mir-548h-2, hsa-mir-548h-3, hsa-mir-548h-4, hsa-mir-548p, hsa-mir-548i-1, hsa-mir-548i-2, hsa-mir-548i-3, hsa-mir-548i-4, hsa-mir-664a, hsa-mir-103b-1, hsa-mir-103b-2, hsa-mir-548q, hsa-mir-548s, hsa-mir-548t, hsa-mir-548u, hsa-mir-3146, hsa-mir-548v, hsa-mir-3174, hsa-mir-548w, hsa-mir-3192, hsa-mir-548x, hsa-mir-3662, hsa-mir-548y, hsa-mir-548z, hsa-mir-548aa-1, hsa-mir-548aa-2, hsa-mir-548o-2, hsa-mir-548h-5, hsa-mir-548ab, hsa-mir-548ac, hsa-mir-548ad, hsa-mir-548ae-1, hsa-mir-548ae-2, hsa-mir-548ag-1, hsa-mir-548ag-2, hsa-mir-548ah, hsa-mir-548ai, hsa-mir-548aj-1, hsa-mir-548aj-2, hsa-mir-548x-2, hsa-mir-548ak, hsa-mir-548al, hsa-mir-548am, hsa-mir-548an, hsa-mir-548ao, hsa-mir-548ap, hsa-mir-548aq, hsa-mir-548ar, hsa-mir-548as, hsa-mir-664b, hsa-mir-548at, hsa-mir-548au, hsa-mir-548av, hsa-mir-548aw, hsa-mir-548ax, hsa-mir-548ay, hsa-mir-548az, hsa-mir-548ba, hsa-mir-548bb, hsa-mir-548bc
Moreover, we also found a number of newly identified miRNAs that were expressed only in the L1-silenced cells although at low levels, including miR-3662, miR-3174, miR-3146, miR-3192 and miR-3605-5p (Supplementary Table S1). [score:3]
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5
[+] score: 1
As a result, the MirGeneDB contains only 7 human and mouse mirtron entries (mmu-mir-1981, mmu-mir-3097, hsa-mir-3605, hsa-mir-3940, hsa-mir-4640, hsa-mir-5010, hsa-mir-6746). [score:1]
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