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6 publications mentioning ccr-let-7j

Open access articles that are associated with the species Cyprinus carpio and mention the gene name let-7j. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 50
In primordial gonad, 3,622 miRNAs were up-regulated, including let-7, while 131 miRNAs were down-regulated, and 1,627 miRNAs were down-regulated in adult ovary, while 107 were up-regulated. [score:13]
A total of 3,558 miRNAs were down-regulated in the complete yolk sac absorption stage compared with juvenile ovary, including let-7, while 377 miRNAs were up-regulated. [score:6]
Numbers in parentheses represents numbers of co-expressed or differentially expressed miRNAs Let-7, which is one of the most conserved miRNAs, has evolved into an miRNA family represented by eight members in Yellow River carp. [score:5]
Numbers in parentheses represents numbers of co-expressed or differentially expressed miRNAs Let-7, which is one of the most conserved miRNAs, has evolved into an miRNA family represented by eight members in Yellow River carp. [score:5]
Let-7 was the most significantly differentially expressed miRNA during the process of ovary development in the current study, with a significant increase from the neurula stage to juvenile ovary. [score:4]
MiR-122, let-7, miR-192, miR-21, miR-499, miR-146, miR-101, miR-128, miR-26, and miR-124 were highly expressed in adult bighead carp and silver carp [54]. [score:3]
Let-7 was another highly-expressed miRNA family in all five stages in the current study. [score:3]
Let-7 was the third most highly expressed miRNA in all five stages in Yellow River carp. [score:3]
Among them, miR-430-3p, miR-19-3p, miR-143-3p, miR-202-5p, miR-30-5p, miR-122-5p, let-7-5p, miR-451-5p, miR-223-3p, and miR-216-5p were the highest-expressed miRNAs in the five periods. [score:3]
Overall, these results suggest that miR-430, miR-21, let-7, miR-181a, and miR-143 may play important roles in ovary differentiation and development in Yellow River carp. [score:2]
The let-7 family was first discovered and characterized in Caenorhabditis elegans, and plays an important role in regulating late developmental events by down regulating lin-41 and possibly other genes [65]. [score:2]
Many other miRNA families were among the conserved Yellow River carp miRNAs, of which miR-100, miR-92, miR-124, miR-200, and miR-184, together with let-7, were the most highly conserved. [score:1]
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2
[+] score: 14
Another highly expressed miRNA family is let-7, such as let-7a-5p, let-7g-5p, let-7i-5p, let-7d-5p, let-7e-5p (S7 Table). [score:3]
These findings implied that highly expressed let-7 family members may also functional constraint and involved in multiple biological activities of G. przewalskii. [score:3]
In addition, a number of let-7 family members were highly expressed in G. przewalskii. [score:3]
Past evidences revealed that let-7 have diverse functions involved into different biological processes, including cell proliferation, development, growth and immune [47]. [score:2]
Conservation and diversity of predicted miRNA families in G. przewalskiiThe largest miRNA families were miR30 and let-7, which both had ten members (Table 1). [score:1]
We also found that let-7 family had the largest number of family members in G. przewalskii. [score:1]
The largest miRNA families were miR30 and let-7, which both had ten members (Table 1). [score:1]
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3
[+] score: 10
This miRNA family plays a role in regulating late developmental events by down regulating lin-41 [30] and possibly other genes which also contain sequences complementary to the seed region in their 3′ UTRs, possibly as a result of its vital role in developmental timing, let-7 was identified as a highly expressed miRNA in bighead and silver carp (602885 and 687481 sequences, respectively). [score:7]
Table S5 Comparison of ten let-7 family members in bighead carp and silver carp. [score:1]
The comparison of let-7 precursors among silver carp (Hypophthalmichthys molitrix), zebrafish (Danio rerio), human (Homo sapiens), fruit fly (Drosophila melanogaster) and nematode (Caenorhabditis elegans) showed the conservation of let-7 mature sequence between vertebrates (above the horizontal line) and invertebrates (below the horizontal line); while the star sequence, though conserved in vertebrates, was less conserved between vertebrates and invertebrates. [score:1]
Another highly-expressed miRNA family is let-7, a highly significant miRNA family that was first discovered and characterized in Caenorhabditis elegans. [score:1]
[1 to 20 of 4 sentences]
4
[+] score: 8
Two let-7 family members, let-7d-3p and let-7c-1-3p were downregulated and they are involved in responses to rapid heat stress, which is similar to let-7c and let-7d expression pattern in response to heat stress in rat small intestine [62]. [score:6]
Let-7 was subsequently identified as the first known C elegans miRNA [63]. [score:1]
let-7 and its family members are highly conserved across species in sequence and function, such as cell proliferation and growth pathways [64]. [score:1]
[1 to 20 of 3 sentences]
5
[+] score: 4
Only let-7, miR-1, and miR-139 are highly conserved from worm to human, but 96 common carp miRNAs are conserved in all vertebrate mo del animals (Table S1), although there exist base edition and length change of sequences across the different animal species. [score:1]
Apart from let-7, 32 other miRNA families were found to be included in the 188 conserved common carp miRNAs. [score:1]
Comparation of the member sequences of the let-7 family in mo del vertebrate animals. [score:1]
Let-7, one of the most conserved miRNAs, has evolved into a miRNA family that includes 8 members in the common carp. [score:1]
[1 to 20 of 4 sentences]
6
[+] score: 1
Six miRNA families (mir-124, mir-9, mir-137, mir-7, mir-306 and let-7) were shared by both protostomes and deuterostomes; 17 miRNAs families were present only in vertebrates; and the remaining two miRNA families (mir-430 and mir-727) were identified only in fish and were possibly fish-specific miRNAs. [score:1]
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