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8 publications mentioning oar-mir-26a

Open access articles that are associated with the species Ovis aries and mention the gene name mir-26a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 40
Other miRNAs from this paper: oar-mir-411b, oar-mir-487a, oar-mir-19b
For example, the differentially expressed miRNA in the infarcted area was oar-miR-19b; the differentially expressed miRNAs in the infarct boundary area included downregulated oar-miR411b-5p, oar-miR-487a-5p, and upregulated oar-miR-26a. [score:11]
Compared with control group, the differentially expressed miRNA in Infarct Zone was oar-miR-19b in the unloading group, while there were three differentially expressed miRNA in Infarct Border Zone (Figures 4(f), 4(g), and 4(h)) including downregulated oar-miR411b-5p and oar-miR-487a-5p and upregulated oar-miR-26a. [score:10]
The GO and KEGG pathway annotations and enrichment were performed in two differentially expressed miRNAs (oar-miR-19b and oar-miR-26a) as shown in Figure 6. The HF is associated with remo deling, which includes the reverse changes of myocardial cells, structures, and functions [22]. [score:3]
The GO and KEGG pathway annotations and enrichment were performed in two differentially expressed miRNAs (oar-miR-19b and oar-miR-26a) as shown in Figure 6. Of the 5 cases in the unloading group, 3 cases survived, 1 case died of ventricular fibrillation, and 1 case died of postoperative cardiac rupture. [score:3]
The results are shown in Figure 5. The difference in oar-miR-19b (P < 0.05) and oar-miR-26a (P < 0.01) expression between unloading group and control group was significant. [score:3]
The GO and KEGG pathway annotations and enrichment were performed in two differentially expressed miRNAs (oar-miR-19b and oar-miR-26a) as shown in Figure 6. Pearson's correlation coefficient between samples was calculated according to the normalized miRNA expression level in each sample. [score:3]
The RT-PCR was used for verification of the differentially expressed miRNAs including oar-miR-19b, oar-miR-26a, oar-miR411b-5p, and oar-miR-487a-5p, which were screened by microarray. [score:3]
Next we will do miR-19b and miR-26a function validation further. [score:1]
The oar-miR-26a was related to the functions of reentry into the mitotic cell cycle, leukocyte mediated immunity, gap junction channel activity, and the signaling pathways of Lysosome, Jak-STAT signaling pathway, and adrenergic signaling in cardiomyocytes. [score:1]
In addition, both miR-19b and miR-26a had a human origin and could be further studied. [score:1]
The results of oar-miR-19b and oar-miR-26a were verified by q-PCR. [score:1]
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2
[+] score: 25
The genes that were up-regulated in underfed males have been implicated in the induction of apoptosis (miR-26a) 53 and testis dysfunction (miR-10b) 54, whereas novel-miR-31(miR-34c), which was up-regulated in well-fed males, enhances germinal phenotypes in late spermatogenesis 51. [score:7]
Under-nutrition did not affect the composition of the top ten, but did affect the expression of three of them - specifically, underfed males showed higher expression of oar-miR-10b and oar-miR-26a, and lower expression of novel-miR-31 (miR-34c), than well-fed males. [score:7]
However, expression of three of the top ten miRNAs did differ between treatments – specifically, oar-miR-10b and oar-miR-26a showed greater expression in underfed than well-fed males, whereas novel-miR-31 showed the opposite effect (Fig. 2). [score:5]
Specifically, miR-98 appears to regulate germ cell apoptosis by changing the expression of CASP3, TP53 and FASL in parallel with the direct effects of miR-26. [score:5]
The other small RNAs that we have detected (miR-26, miR-34c, miR-10b, piR-9006, piR-12568) are involved in the control of reproductive function in other species, so might also contribute to the effects of nutrition on spermatogenesis in the sexually mature sheep. [score:1]
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3
[+] score: 9
For a normaliser miRNA for use with sheep tissues, the expression of three ovine miRNAs (oar-miR-26a, oar-miR-103 and oar-miR-122a) was assessed. [score:3]
oaR-miR-26a was selected as it could be amplified consistently from all ovine abomasal and lymph node samples tested. [score:1]
Oar-miR-122a, Oar-miR-26a and Oar-miR-103 were adapted from their bovine homologues [15], based on the ovine sequence available at NCBI (oar_v3.1). [score:1]
S6 FigqRT-PCR amplification to detect presence of oar-miR-26a in infected and pathogen-free sheep abomasal and draining lymph node tissus. [score:1]
Fluorescence values were normalised to oar-miR-26a qRT-PCR. [score:1]
The data in Fig 4 shows the signal obtained from infected and uninfected tissues for all three miRNAs normalised to oar-miR-26a (see Materials and and S6 Fig). [score:1]
qRT-PCR amplification to detect presence of oar-miR-26a in infected and pathogen-free sheep abomasal and draining lymph node tissus. [score:1]
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4
[+] score: 4
The mir-10 (MIPF0000033), mir-143 (MIPF0000094), let-7 (MIPF0000002) and mir-26 (MIPF0000043) families were found to be preferentially expressed in ovine ovary. [score:3]
Some of the abundant miRNAs in the anestrous ovary of Tan sheep, including miR-143, miR-26a, let-7 and miR-21, were also reported to be highly abundant in ovaries of human, cow [23– 25], pig [26], adult and neonatal mouse [27, 28] and sheep [2, 3]. [score:1]
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5
[+] score: 4
However, oar_circ_0000043 included target sites for miRNA-10b, miRNA-134, miRNA-148, miRNA-181, miRNA-200, miRNA-26, and miRNA-30. [score:3]
Furthermore, we determined that various circRNAs interact with different pituitary gland-related miRNAs, such as miR-181, miR-133, miR-26, and miR-329 (Table  S4). [score:1]
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6
[+] score: 4
We further analyzed the microarray result and found that only 22 miRNAs; let-7a, let-7c, miR-1, miR-206, miR-133a, miR-133b, miR-128–1, miR-128–2, miR-140, miR-143, miR-199a, miR-22, miR-26a, miR-27b, miR-29a, miR-29c, miR-378–1, miR-378–2, miR-486, miR-499, miR-99a and miR-101–2 have high levels of expression. [score:3]
There were six pri-miRNAs, such as pri-miR-499, pri-miR-26a and pri-378–1, in which no genetic variations were observed in sheep. [score:1]
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7
[+] score: 3
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-21, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-26a-1, hsa-mir-29a, hsa-mir-30a, hsa-mir-31, hsa-mir-99a, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-16-2, hsa-mir-192, hsa-mir-148a, hsa-mir-10b, hsa-mir-181a-2, hsa-mir-181a-1, hsa-mir-215, hsa-mir-223, hsa-mir-224, hsa-mir-200b, hsa-mir-15b, hsa-mir-27b, hsa-mir-125b-1, hsa-mir-141, hsa-mir-143, hsa-mir-152, hsa-mir-125b-2, hsa-mir-126, hsa-mir-146a, hsa-mir-184, hsa-mir-200c, hsa-mir-155, hsa-mir-29c, hsa-mir-200a, hsa-mir-99b, hsa-mir-296, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-378a, hsa-mir-342, hsa-mir-148b, hsa-mir-451a, ssc-mir-125b-2, ssc-mir-148a, ssc-mir-15b, ssc-mir-184, ssc-mir-224, ssc-mir-23a, ssc-mir-24-1, ssc-mir-26a, ssc-mir-29b-1, ssc-let-7f-1, ssc-mir-103-1, ssc-mir-21, ssc-mir-29c, hsa-mir-486-1, hsa-mir-499a, hsa-mir-671, hsa-mir-378d-2, bta-mir-26a-2, bta-mir-29a, bta-let-7f-2, bta-mir-103-1, bta-mir-148a, bta-mir-16b, bta-mir-21, bta-mir-499, bta-mir-99a, bta-mir-125b-1, bta-mir-126, bta-mir-181a-2, bta-mir-27b, bta-mir-31, bta-mir-15b, bta-mir-215, bta-mir-30e, bta-mir-148b, bta-mir-192, bta-mir-200a, bta-mir-200c, bta-mir-23a, bta-mir-29b-2, bta-mir-29c, bta-mir-10b, bta-mir-24-2, bta-mir-30a, bta-mir-200b, bta-let-7a-1, bta-mir-342, bta-let-7f-1, bta-let-7a-2, bta-let-7a-3, bta-mir-103-2, bta-mir-125b-2, bta-mir-15a, bta-mir-99b, hsa-mir-664a, ssc-mir-99b, hsa-mir-103b-1, hsa-mir-103b-2, ssc-mir-15a, ssc-mir-16-2, ssc-mir-16-1, bta-mir-141, bta-mir-143, bta-mir-146a, bta-mir-152, bta-mir-155, bta-mir-16a, bta-mir-184, bta-mir-24-1, bta-mir-223, bta-mir-224, bta-mir-26a-1, bta-mir-296, bta-mir-29d, bta-mir-378-1, bta-mir-451, bta-mir-486, bta-mir-671, bta-mir-29e, bta-mir-29b-1, bta-mir-181a-1, ssc-mir-181a-1, ssc-mir-215, ssc-mir-30a, bta-mir-2318, bta-mir-2339, bta-mir-2430, bta-mir-664a, bta-mir-378-2, ssc-let-7a-1, ssc-mir-378-1, ssc-mir-29a, ssc-mir-30e, ssc-mir-499, ssc-mir-143, ssc-mir-10b, ssc-mir-486-1, ssc-mir-152, ssc-mir-103-2, ssc-mir-181a-2, ssc-mir-27b, ssc-mir-24-2, ssc-mir-99a, ssc-mir-148b, ssc-mir-664, ssc-mir-192, ssc-mir-342, ssc-mir-125b-1, oar-mir-21, oar-mir-29a, oar-mir-125b, oar-mir-181a-1, hsa-mir-378b, hsa-mir-378c, ssc-mir-296, ssc-mir-155, ssc-mir-146a, bta-mir-148c, ssc-mir-126, ssc-mir-378-2, ssc-mir-451, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-451b, hsa-mir-499b, ssc-let-7a-2, ssc-mir-486-2, hsa-mir-664b, hsa-mir-378j, ssc-let-7f-2, ssc-mir-29b-2, ssc-mir-31, ssc-mir-671, bta-mir-378b, bta-mir-378c, hsa-mir-486-2, oar-let-7a, oar-let-7f, oar-mir-103, oar-mir-10b, oar-mir-143, oar-mir-148a, oar-mir-152, oar-mir-16b, oar-mir-181a-2, oar-mir-200a, oar-mir-200b, oar-mir-200c, oar-mir-23a, oar-mir-29b-1, oar-mir-30a, oar-mir-99a, bta-mir-664b, chi-let-7a, chi-let-7f, chi-mir-103, chi-mir-10b, chi-mir-125b, chi-mir-126, chi-mir-141, chi-mir-143, chi-mir-146a, chi-mir-148a, chi-mir-148b, chi-mir-155, chi-mir-15a, chi-mir-15b, chi-mir-16a, chi-mir-16b, chi-mir-184, chi-mir-192, chi-mir-200a, chi-mir-200b, chi-mir-200c, chi-mir-215, chi-mir-21, chi-mir-223, chi-mir-224, chi-mir-2318, chi-mir-23a, chi-mir-24, chi-mir-26a, chi-mir-27b, chi-mir-296, chi-mir-29a, chi-mir-29b, chi-mir-29c, chi-mir-30a, chi-mir-30e, chi-mir-342, chi-mir-378, chi-mir-451, chi-mir-499, chi-mir-671, chi-mir-99a, chi-mir-99b, bta-mir-378d, ssc-mir-378b, oar-mir-29b-2, ssc-mir-141, ssc-mir-200b, ssc-mir-223, bta-mir-148d
Additionally, a number of miRNAs including miR-148a, miR-26a, miR-21-5p, miR-27b, miR-143, bta-miR-30a-5p, let-7a-5p, let-7f, miR-10b, and miR-99a-5p are highly expressed in bovine mammary gland/mammary epithelial cells (Li et al., 2012a, 2014a; Jin et al., 2014a; Le Guillou et al., 2014) suggesting roles in the lactation process and mammary gland functions. [score:3]
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8
[+] score: 1
In the DU, CE, and CO libraries, miR-143 had the largest number of reads, while the miR-21, miR-148a, miR-26, and let-7 families were the next most abundant. [score:1]
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