Stem-loop mml-mir-15b

Accession

MI0002496

Description

Macaca mulatta mml-mir-15b precursor miRNA mir-15

Gene
family

RF00455; mir-15

Literature search

1 open access papers mention mml-mir-15b
(3 sentences)

Sequence

4491 reads, 81 reads per million, 9 experiments

uugaggccuuaaaguacugUAGCAGCACAUCAUGGUUUACAuacuacagucaagaugCGAAUCAUUAUUUGCUGCUCUAgaaauuuaaggaaauucau
.((((.(((((((...(((.(((((((.((.(((((((.(((.((.......))))).))))))).)).))))))).)))...)))))))...)))).

Structure

u    --g       gua   U       C  C       A   a  ac 
 ugag   ccuuaaa   cug AGCAGCA AU AUGGUUU CAu cu  a
 ||||   |||||||   ||| ||||||| || ||||||| ||| ||  g
 acuu   ggaauuu   gAU UCGUCGU UA UACUAAG gua ga  u
u    aaa       aaa   C       U  U       C   -  ac 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr2: 134308684-134308781 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mml-mir-15b

Mature mml-miR-15b-5p

• Accession: MIMAT0002207
• Description: Macaca mulatta mml-miR-15b-5p mature miRNA
• Sequence: 20 - UAGCAGCACAUCAUGGUUUACA - 41
• Evidence: experimental ; Illumina [2]

Mature mml-miR-15b-3p

• Accession: MIMAT0026562
• Description: Macaca mulatta mml-miR-15b-3p mature miRNA
• Sequence: 58 - CGAAUCAUUAUUUGCUGCUCUA - 79
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45