Stem-loop mml-mir-21

Accession

MI0002621

Description

Macaca mulatta mml-mir-21 precursor miRNA mir-21

Gene
family

RF00658; mir-21

Literature search

7 open access papers mention mml-mir-21
(102 sentences)

Sequence

1927905 reads, 16314 reads per million, 9 experiments

ugucgggUAGCUUAUCAGACUGAUGUUGAcuguugaaucucauggCAACACCAGUCGAUGGGCUGUCugaca
((((((((((((((((.(((((.(((((.((((.((...))))))))))).)))))))))))))))))))))

Structure

                A     A     A    u  a 
ugucgggUAGCUUAUC GACUG UGUUG cugu ga  
|||||||||||||||| ||||| ||||| |||| || u
acaguCUGUCGGGUAG CUGAC ACAAC ggua cu  
                -     C     -    -  c 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr16: 53341909-53341980 [+]

Mature mml-miR-21-5p

• Accession: MIMAT0002320
• Description: Macaca mulatta mml-miR-21-5p mature miRNA
• Sequence: 8 - UAGCUUAUCAGACUGAUGUUGA - 29
• Evidence: experimental ; Illumina [2]

Mature mml-miR-21-3p

• Accession: MIMAT0026573
• Description: Macaca mulatta mml-miR-21-3p mature miRNA
• Sequence: 46 - CAACACCAGUCGAUGGGCUGUC - 67
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45