Stem-loop hsa-mir-504

Accession

MI0003189

Symbol

HGNC: MIR504

Description

Homo sapiens hsa-mir-504 precursor miRNA mir-504

Gene
family

RF00939; mir-504

Literature search

27 open access papers mention hsa-mir-504
(170 sentences)

Sequence

2572 reads, 32 reads per million, 112 experiments

gcugcuguugggAGACCCUGGUCUGCACUCUAUCuguauucuuacugaaGGGAGUGCAGGGCAGGGUUUCccauacagagggc
(((.((((((((((((((((.((((((((((.((.(((....))).))..)))))))))).)))))))))))).))))..)))

Structure

   -g    -            G          -A  u   u 
gcu  cugu ugggAGACCCUG UCUGCACUCU  UC gua u
|||  |||| |||||||||||| ||||||||||  || |||  
cgg  gaca accCUUUGGGAC GGACGUGAGG  ag cau c
   ga    u            G          Ga  u   u 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chrX: 138667711-138667793 [-]

Disease association

hsa-mir-504 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-504-5p

• Accession: MIMAT0002875
• Description: Homo sapiens hsa-miR-504-5p mature miRNA
• Sequence: 13 - AGACCCUGGUCUGCACUCUAUC - 34
• Evidence: experimental ; array-cloned [1], cloned [2], Illumina [3]

Mature hsa-miR-504-3p

• Accession: MIMAT0026612
• Description: Homo sapiens hsa-miR-504-3p mature miRNA
• Sequence: 50 - GGGAGUGCAGGGCAGGGUUUC - 70
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45