miRBase entry: cre-MIR908

Stem-loop cre-MIR908


Accession
MI0005701
Description
Chlamydomonas reinhardtii cre-MIR908 precursor miRNA


Sequence

guggguuuUGAGAAGAUGCGGUCCGUUGGCuauaauguugacagaccacccgcucccuuacugacgcaguUGACGCGUUUGAUAGCAGGAUCauaguacgggaccaguuccccuaccaacuggucccguaaccacuaugauccugcuaucaaaggcgucaACUACGUCAAUAAGGCAGCggguggucaauauacauuauugccaacggaccgguucuccucaaaugucac
((((..((((((.(((..((((((((((((.(((((((.....(((((((((((.(((((.(((((.(((((((((.((((((((((((((((((((((((((((((((........))))))))))))....)))))))))))))))))))).))))))))).))))).))))).))))))))))).....))))))).))))))))))))..))).))))))..))))

Structure
    gu      A   UG            u       ugaca           c     c     c         G                    ----            ccc 
gugg  uuUGAG AGA  CGGUCCGUUGGC auaaugu     gaccacccgcu ccuua ugacg aguUGACGC UUUGAUAGCAGGAUCauagu    acgggaccaguu   c
||||  |||||| |||  |||||||||||| |||||||     ||||||||||| ||||| ||||| ||||||||| ||||||||||||||||||||    ||||||||||||    
cacu  aaacuc ucu  gccaggcaaccg uauuaca     cuggugggCGA GGAAU ACUGC UCAacugcg aaacuaucguccuaguauca    ugcccuggucaa   u
    gu      c   ug            u       uauaa           C     A     A         g                    ccaa            cca 


Annotation confidence Not enough data
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Comments
Zhao et al. identify a mature miRNA product from the 5' arm of the hairpin precursor, and named it miR908 [1]. Molner et al. identify 3 mature products, and suggest that an alternative 5' product is the predominant one, named cre-miR908.1 here [2]. The Zhao et al. product is renamed miR908.2 here.

Genome context
scaffold_213: 20092-20321 [+]

Database links

Mature cre-miR908.1

Accession MIMAT0004965
Description Chlamydomonas reinhardtii cre-miR908.1 mature miRNA
Sequence 9 - UGAGAAGAUGCGGUCCGUUGGC - 30
Evidence experimental
cloned [2]

Mature cre-miR908.2

Accession MIMAT0004390
Description Chlamydomonas reinhardtii cre-miR908.2 mature miRNA
Sequence 71 - UGACGCGUUUGAUAGCAGGAUC - 92
Evidence experimental
cloned [1-2]

Mature cre-miR908.3

Accession MIMAT0004966
Description Chlamydomonas reinhardtii cre-miR908.3 mature miRNA
Sequence 161 - ACUACGUCAAUAAGGCAGC - 179
Evidence experimental
cloned [2]

References

  1. PubMed ID: 17470535
    A complex system of small RNAs in the unicellular green alga Chlamydomonas reinhardtii
    "Zhao T, Li G, Mi S, Li S, Hannon GJ, Wang XJ, Qi Y"
    "Genes Dev (2007) 21:1190-1203

  2. PubMed ID: 17538623
    miRNAs control gene expression in the single-cell alga Chlamydomonas reinhardtii
    "Molnar A, Schwach F, Studholme DJ, Thuenemann EC, Baulcombe DC"
    "Nature (2007) 447:1126-1129