miRBase entry: blv-mir-B4

Stem-loop blv-mir-B4

Accession

MI0022564

Description

Bovine leukemia virus blv-mir-B4 precursor miRNA

Sequence

GCGGGAGGCUCUGGUGCUGGggauaagauguggcccuUAGCACCACAGUCUCUGCGCCUUU
((((((((((.(((((((((((............))))))))))).))))))).)))....

Structure

----   -       C           auaag 
    GCG GGAGGCU UGGUGCUGGgg     a
    ||| ||||||| |||||||||||      
    CGC UCUCUGA ACCACGAUucc     u
UUUC   G       C           cggug

Annotation confidence Not enough data

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Genome context

K02120.1: 6702-6762 [+]

Clustered miRNAs

4 other miRNAs are < 10 kb from blv-mir-B4

Name	Accession	Chromosome	Start	End	Strand	Confidence

Database links

Mature blv-miR-B4-3p

Accession	MIMAT0025864
Description	Bovine leukemia virus blv-miR-B4-3p mature miRNA
Sequence	38 - UAGCACCACAGUCUCUGCGCCUUU - 61
Evidence	experimental SOLiD [1], Illumina [2]

Mature blv-miR-B4-5p

Accession	MIMAT0027347
Description	Bovine leukemia virus blv-miR-B4-5p mature miRNA
Sequence	1 - GCGGGAGGCUCUGGUGCUGG - 20
Evidence	experimental Illumina [2]

References

PubMed ID: 22308400
RNA virus microRNA that mimics a B-cell oncomiR
"Kincaid RP, Burke JM, Sullivan CS"
"Proc Natl Acad Sci U S A (2012) 109:3077-3082

PubMed ID: 23345446
Deep sequencing reveals abundant noncanonical retroviral microRNAs in B-cell leukemia/lymphoma
"Rosewick N, Momont M, Durkin K, Takeda H, Caiment F, Cleuter Y, Vernin C, Mortreux F, Wattel E, Burny A, Georges M, Van den Broeke A"
"Proc Natl Acad Sci U S A (2013) 110:2306-2311