Stem-loop sequence dme-mir-2b-1

AccessionMI0000119 (change log)
DescriptionDrosophila melanogaster miR-2b-1 stem-loop
Gene family MIPF0000049; mir-2
Literature search

28 open access papers mention dme-mir-2b-1
(114 sentences)

     u    ug         -    a    ----c      u 
5' cu caac  ucuucaaag uggc guga     auguug c
   || ||||  ||||||||| |||| ||||     ||||||  
3' gg guug  aggaguuuc accg cacu     uauaac a
     c    cg         g    a    auacu      a 
Get sequence
Deep sequencing
1099244 reads, 1.95e+04 reads per million, 49 experiments
Confidence Annotation confidence: high
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Stark et al. [2] have identified targets for miR-2 in Drosophila using computational prediction followed by experimental validation. miR-2 regulates the proapoptotic genes reaper, grim and sickle, suggesting that it may be involved in the control of apoptosis.

Genome context
Coordinates (Release_6; GCA_000001215.4) Overlapping transcripts
chr2L: 8258616-8258692 [-]
Database links

Mature sequence dme-miR-2b-1-5p

Accession MIMAT0020782

9 - 


 - 31

Get sequence
Deep sequencing1863 reads, 46 experiments
Evidence not experimental
Database links

Mature sequence dme-miR-2b-3p

Accession MIMAT0000107
Previous IDsdme-miR-2b

48 - 


 - 70

Get sequence
Deep sequencing2265994 reads, 49 experiments
Evidence experimental; cloned [1,4], Northern [1,3], 454 [5-6], Illumina [6]
Database links
Predicted targets


PMID:11679670 "Identification of novel genes coding for small expressed RNAs" Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T Science. 294:853-858(2001).
PMID:14691535 "Identification of Drosophila MicroRNA targets" Stark A, Brennecke J, Russell RB, Cohen SM PLoS Biol. 1:E60(2003).
PMID:12919683 "The small RNA profile during Drosophila melanogaster development" Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T Dev Cell. 5:337-350(2003).
PMID:17989254 "Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs" Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC Genome Res. 17:1850-1864(2007).
PMID:17989255 "Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes" Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M Genome Res. 17:1865-1879(2007).