miRBase entry: mmu-mir-15b

Stem-loop mmu-mir-15b


Accession
MI0000140
Symbol
MGI: Mir15b
Description
Mus musculus mmu-mir-15b precursor miRNA
Gene family
MIPF0000006; mir-15

Literature search
162 open access papers mention mmu-mir-15b
(835 sentences)

Sequence

282093 reads, 1511 reads per million, 109 experiments
cugUAGCAGCACAUCAUGGUUUACAuacuacagucaagaugCGAAUCAUUAUUUGCUGCUCUAg
(((.(((((((.((.(((((((.(((.((.......))))).))))))).)).))))))).)))

Structure
   U       C  C       A   a  ac 
cug AGCAGCA AU AUGGUUU CAu cu  a
||| ||||||| || ||||||| ||| ||  g
gAU UCGUCGU UA UACUAAG gua ga  u
   C       U  U       C   -  ac 


Annotation confidence High
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Genome context
chr3: 69009772-69009835 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from mmu-mir-15b
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-15b-5p

Accession MIMAT0000124
Description Mus musculus mmu-miR-15b-5p mature miRNA
Sequence 4 - UAGCAGCACAUCAUGGUUUACA - 25
Evidence experimental
cloned [1-2,4-6], Illumina [7-8]
Database links
Predicted targets

Mature mmu-miR-15b-3p

Accession MIMAT0004521
Description Mus musculus mmu-miR-15b-3p mature miRNA
Sequence 42 - CGAAUCAUUAUUUGCUGCUCUA - 63
Evidence experimental
cloned [6], Illumina [7-8]
Database links
Predicted targets

References

  1. PubMed ID: 12554860
    Numerous microRNPs in neuronal cells containing novel microRNAs
    "Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G"
    "RNA (2003) 9:180-186

  2. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  3. PubMed ID: 12919684
    Embryonic stem cell-specific MicroRNAs
    "Houbaviy HB, Murray MF, Sharp PA"
    "Dev Cell (2003) 5:351-358

  4. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739

  5. PubMed ID: 15538371
    A pancreatic islet-specific microRNA regulates insulin secretion
    "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
    "Nature (2004) 432:226-230

  6. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  7. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  8. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009