miRBase entry: mmu-mir-27b

Stem-loop mmu-mir-27b


Accession
MI0000142
Symbol
MGI: Mir27b
Description
Mus musculus mmu-mir-27b precursor miRNA
Gene family
MIPF0000036; mir-27

Literature search
128 open access papers mention mmu-mir-27b
(567 sentences)

Sequence

1724881 reads, 5539 reads per million, 107 experiments
aggugcAGAGCUUAGCUGAUUGGUGAACagugauugguuuccgcuuugUUCACAGUGGCUAAGUUCUGCaccu
(((((((((((((((((.((((.(((((((....(((...)))..))))))))))))))))))))))))))))

Structure
                 G    G       ugau   u 
aggugcAGAGCUUAGCU AUUG UGAACag    ugg  
||||||||||||||||| |||| |||||||    ||| u
uccaCGUCUUGAAUCGG UGAC ACUUguu    gcc  
                 -    -       --uc   u 


Annotation confidence High
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Genome context
chr13: 63300712-63300784 [+]
Clustered miRNAs
3 other miRNAs are < 10 kb from mmu-mir-27b
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-27b-5p

Accession MIMAT0004522
Description Mus musculus mmu-miR-27b-5p mature miRNA
Sequence 7 - AGAGCUUAGCUGAUUGGUGAAC - 28
Evidence experimental
cloned [5], Illumina [6-7]
Database links
Predicted targets

Mature mmu-miR-27b-3p

Accession MIMAT0000126
Description Mus musculus mmu-miR-27b-3p mature miRNA
Sequence 49 - UUCACAGUGGCUAAGUUCUGC - 69
Evidence experimental
cloned [1,3-5], Illumina [6-7]
Database links
Predicted targets

References

  1. PubMed ID: 12554860
    Numerous microRNPs in neuronal cells containing novel microRNAs
    "Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G"
    "RNA (2003) 9:180-186

  2. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  3. PubMed ID: 12919684
    Embryonic stem cell-specific MicroRNAs
    "Houbaviy HB, Murray MF, Sharp PA"
    "Dev Cell (2003) 5:351-358

  4. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739

  5. PubMed ID: 15538371
    A pancreatic islet-specific microRNA regulates insulin secretion
    "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
    "Nature (2004) 432:226-230

  6. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  7. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009