miRBase entry: mmu-mir-136

Stem-loop mmu-mir-136


Accession
MI0000162
Symbol
MGI: Mir136
Description
Mus musculus mmu-mir-136 precursor miRNA
Gene family
MIPF0000099; mir-136

Literature search
24 open access papers mention mmu-mir-136
(149 sentences)

Sequence

323341 reads, 3769 reads per million, 85 experiments
gaggACUCCAUUUGUUUUGAUGAUGGauucuuaagcuccAUCAUCGUCUCAAAUGAGUCUUc
((((((((.(((((...((((((((((.........))))))))))...)))))))))))))

Structure
        C     UUU          uuc 
gaggACUC AUUUG   UGAUGAUGGa   u
|||||||| |||||   ||||||||||   u
cUUCUGAG UAAAC   GCUACUAccu   a
        -     UCU          cga 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [4].

Genome context
chr12: 109595327-109595388 [+]
Clustered miRNAs
12 other miRNAs are < 10 kb from mmu-mir-136
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-136-5p

Accession MIMAT0000148
Description Mus musculus mmu-miR-136-5p mature miRNA
Sequence 5 - ACUCCAUUUGUUUUGAUGAUGG - 26
Evidence experimental
cloned [1-2,4], PCR [3], Illumina [5-6]
Database links
Predicted targets

Mature mmu-miR-136-3p

Accession MIMAT0004532
Description Mus musculus mmu-miR-136-3p mature miRNA
Sequence 40 - AUCAUCGUCUCAAAUGAGUCUU - 61
Evidence experimental
cloned [4], Illumina [5-6]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739

  3. PubMed ID: 15538371
    A pancreatic islet-specific microRNA regulates insulin secretion
    "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
    "Nature (2004) 432:226-230

  4. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  5. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  6. PubMed ID: 15854907
    RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11 locus
    "Davis E, Caiment F, Tordoir X, Cavaille J, Ferguson-Smith A, Cockett N, Georges M, Charlier C"
    "Curr Biol (2005) 15:743-749