miRBase entry: mmu-mir-142a

Stem-loop mmu-mir-142a


Accession
MI0000167
Description
Mus musculus mmu-mir-142a precursor miRNA
Gene family
MIPF0000084; mir-142

Literature search
165 open access papers mention mmu-mir-142a
(2162 sentences)

Sequence

1951239 reads, 7048 reads per million, 102 experiments
accCAUAAAGUAGAAAGCACUACUaacagcacuggagggUGUAGUGUUUCCUACUUUAUGGAug
..(((((((((((.(((((((((...(..(....)..)..))))))))).)))))))))))...

Structure
-ac           A         Uaa ag a 
   cCAUAAAGUAG AAGCACUAC   c  c c
   ||||||||||| |||||||||   |  |  
   GGUAUUUCAUC UUUGUGAUG   g  g u
guA           C         -Ug ga g 


Annotation confidence Not enough data
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Comments
Expression of miRNAs from both 5' and 3' arms of this precursor have been independently verified in the mouse gut tissue [1] and in embryonic stem cells [2]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context
chr11: 87756864-87756927 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from mmu-mir-142a
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-142a-5p

Accession MIMAT0000154
Description Mus musculus mmu-miR-142a-5p mature miRNA
Sequence 4 - CAUAAAGUAGAAAGCACUACU - 24
Evidence experimental
cloned [1-3], Illumina [4-5]
Database links
Predicted targets

Mature mmu-miR-142a-3p

Accession MIMAT0000155
Description Mus musculus mmu-miR-142a-3p mature miRNA
Sequence 40 - UGUAGUGUUUCCUACUUUAUGGA - 62
Evidence experimental
cloned [1-3], Illumina [4-5]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12919684
    Embryonic stem cell-specific MicroRNAs
    "Houbaviy HB, Murray MF, Sharp PA"
    "Dev Cell (2003) 5:351-358

  3. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739

  4. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  5. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009