miRBase entry: mmu-mir-145a

Stem-loop mmu-mir-145a


Accession
MI0000169
Symbol
MGI: Mir145a
Description
Mus musculus mmu-mir-145a precursor miRNA
Gene family
MIPF0000079; mir-145

Literature search
217 open access papers mention mmu-mir-145a
(1869 sentences)

Sequence

98920 reads, 1227 reads per million, 89 experiments
cucacgGUCCAGUUUUCCCAGGAAUCCCUuggaugcuaagauggggAUUCCUGGAAAUACUGUUCUUGag
((((.((..((((.((.((((((((((((.............)))))))))))).)).))))..))))))

Structure
    c  UC    U  C            uggau 
cuca gG  CAGU UU CCAGGAAUCCCU     g
|||| ||  |||| || ||||||||||||     c
gaGU UC  GUCA AA GGUCCUUAgggg     u
    -  UU    U  A            uagaa 


Annotation confidence High
Do you think this miRNA is real?
Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
chr18: 61647825-61647894 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from mmu-mir-145a
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-145a-5p

Accession MIMAT0000157
Description Mus musculus mmu-miR-145a-5p mature miRNA
Sequence 7 - GUCCAGUUUUCCCAGGAAUCCCU - 29
Evidence experimental
cloned [1-2], Illumina [3-4]
Database links
Predicted targets

Mature mmu-miR-145a-3p

Accession MIMAT0004534
Description Mus musculus mmu-miR-145a-3p mature miRNA
Sequence 47 - AUUCCUGGAAAUACUGUUCUUG - 68
Evidence experimental
cloned [2], Illumina [3-4]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739

  3. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  4. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009